ENSMUSG00000042078


Mus musculus

Features
Gene ID: ENSMUSG00000042078
  
Biological name :Svop
  
Synonyms : Q8BFT9 / Svop / Synaptic vesicle 2-related protein
  
Possible biological names infered from orthology : Q8N4V2 / SV2 related protein
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: F
Gene start: 114026910
Gene end: 114091570
  
Corresponding Affymetrix probe sets: 10532784 (MoGene1.0st)   1452663_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117724
Ensembl peptide - ENSMUSP00000050730
NCBI entrez gene - 68666     See in Manteia.
MGI - MGI:1915916
RefSeq - NM_026805
RefSeq - XM_006530455
RefSeq Peptide - NP_081081
swissprot - D3Z379
swissprot - Q8BFT9
Ensembl - ENSMUSG00000042078
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 svopaENSDARG00000056833Danio rerio
 svopbENSDARG00000014951Danio rerio
 SVOPENSGALG00000034278Gallus gallus
 SVOPENSG00000166111Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Svopl / Q6PDF3 / Putative transporter SVOPL / Q8N434* / SVOP like*ENSMUSG0000002983034
Sv2a / Q9JIS5 / Synaptic vesicle glycoprotein 2A / Q7L0J3*ENSMUSG0000003848624
Sv2c / Q69ZS6 / synaptic vesicle glycoprotein 2c / Q496J9*ENSMUSG0000005111123
Sv2b / Q8BG39 / Synaptic vesicle glycoprotein 2B / Q7L1I2*ENSMUSG0000005302523


Protein motifs (from Interpro)
Interpro ID Name
 IPR004749  Organic cation transport protein/SVOP
 IPR005828  Major facilitator, sugar transporter-like
 IPR011701  Major facilitator superfamily
 IPR020846  Major facilitator superfamily domain
 IPR027378  Cyclic nucleotide-regulated ion channel, N-terminal
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030672 synaptic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0022857 transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Sv2atm1Baj/Sv2atm1Baj,Sv2btm1Baj/Sv2btm1Baj,Svoptm1.1Baj/Svoptm1.1Baj
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6Ncr

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Wnk1tm2.1Juha/Wnk1+,Tg(Pgk1-cre)1Lni/0
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Sv2atm1Baj/Sv2atm1Baj,Sv2btm1Baj/Sv2btm1Baj,Svoptm1.1Baj/Svoptm1.1Baj
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6Ncr

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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