ENSMUSG00000042473


Mus musculus

Features
Gene ID: ENSMUSG00000042473
  
Biological name :Tbc1d8b
  
Synonyms : A3KGB4 / Tbc1d8b / TBC1 domain family member 8B
  
Possible biological names infered from orthology : Q0IIM8
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: F1
Gene start: 139684996
Gene end: 139753405
  
Corresponding Affymetrix probe sets: 10602020 (MoGene1.0st)   1421636_at (Mouse Genome 430 2.0 Array)   1430133_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000094036
NCBI entrez gene - 245638     See in Manteia.
MGI - MGI:1918101
RefSeq - NM_001081499
RefSeq - XM_006528546
RefSeq Peptide - NP_001074968
swissprot - A3KGB4
Ensembl - ENSMUSG00000042473
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 B0R0W9ENSDARG00000062192Danio rerio
 TBC1D8BENSGALG00000009040Gallus gallus
 Q0IIM8ENSG00000133138Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9Z1A9 / Tbc1d8 / Mus musculus TBC1 domain family, member 8 (Tbc1d8), transcript variant 3, mRNA. / O95759* / TBC1 domain family member 8*ENSMUSG0000000313453
Q3UYK3 / Tbc1d9 / TBC1 domain family member 9 / Q6ZT07*ENSMUSG0000003170952
Q5SVR0 / Tbc1d9b / TBC1 domain family member 9B / Q66K14*ENSMUSG0000003664452
Q3U0J8 / Tbc1d2b / TBC1 domain family member 2B / Q9UPU7*ENSMUSG0000003741014
B1AVH7 / Tbc1d2 / TBC1 domain family member 2A / Q9BYX2* / TBC1 domain family member 2*ENSMUSG0000003981314
Sgsm3 / Q8VCZ6 / Small G protein signaling modulator 3 / Q96HU1*ENSMUSG0000004230313
Q69ZT9 / Tbc1d30 / TBC1 domain family member 30 / Q9Y2I9*ENSMUSG0000005230211


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain
 IPR002048  EF-hand domain
 IPR004182  GRAM domain
 IPR011992  EF-hand domain pair
 IPR035969  Rab-GTPase-TBC domain superfamily
 IPR036012  TBC1D8B, PH-GRAM domain 1
 IPR036015  TBC1D8B, PH-GRAM domain 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0031338 regulation of vesicle fusion IBA
 biological_processGO:0090630 activation of GTPase activity IBA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0012505 endomembrane system IBA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0017137 Rab GTPase binding IBA


Pathways (from Reactome)
Pathway description
Golgi Associated Vesicle Biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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