ENSMUSG00000044034


Mus musculus

Features
Gene ID: ENSMUSG00000044034
  
Biological name :Npb
  
Synonyms : Mus musculus neuropeptide B (Npb), transcript variant 3, mRNA. / Npb / Q8K4P1
  
Possible biological names infered from orthology : neuropeptide B / Q8NG41
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: E2
Gene start: 120608477
Gene end: 120609093
  
Corresponding Affymetrix probe sets: 10383429 (MoGene1.0st)   1440240_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000101801
Ensembl peptide - ENSMUSP00000050092
Ensembl peptide - ENSMUSP00000101800
NCBI entrez gene - 208990     See in Manteia.
MGI - MGI:2387153
RefSeq - XM_017314407
RefSeq - NM_001347617
RefSeq - NM_153288
RefSeq - XM_017314406
RefSeq Peptide - NP_001334545
RefSeq Peptide - NP_001334546
RefSeq Peptide - NP_695020
swissprot - Q3UR83
swissprot - A2ABY2
swissprot - Q8K4P1
swissprot - A2ABY0
Ensembl - ENSMUSG00000044034
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 npbENSDARG00000078828Danio rerio
 NPBENSGALG00000044431Gallus gallus
 NPBENSG00000183979Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013297  Neuropeptide B/W precursor family
 IPR013298  Neuropeptide B precursor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway ISO
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space ISO
 molecular_functionGO:0001664 G-protein coupled receptor binding IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
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Allelic Composition: Apctm1Kk/Apctm1Kk,Tg(Lck-cre)1Cwi/?
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA/2

Allelic Composition: Npbtm1Ywa/Npb+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0005407 hyperalgesia "increased sensation to painful stimuli that may follow damage to soft tissue containing nociceptors or injury to a peripheral nerve; it can be primary (at the site of the injury) or secondary (in the surrounding undamaged area)" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Apctm1Kk/Apctm1Kk,Tg(Lck-cre)1Cwi/?
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA/2

Allelic Composition: Npbtm1Ywa/Npb+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000033774 Npbwr1 / P49681 / Neuropeptides B/W receptor type 1 / P48145* / neuropeptides B and W receptor 1*  / complex / reaction






 

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