ENSMUSG00000045404


Mus musculus

Features
Gene ID: ENSMUSG00000045404
  
Biological name :Kcnk13
  
Synonyms : Kcnk13 / Potassium channel subfamily K member 13 / Q8R1P5
  
Possible biological names infered from orthology : potassium two pore domain channel subfamily K member 13 / Q9HB14
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: E
Gene start: 99964499
Gene end: 100062682
  
Corresponding Affymetrix probe sets: 10397736 (MoGene1.0st)   1424125_at (Mouse Genome 430 2.0 Array)   1447645_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000051846
Ensembl peptide - ENSMUSP00000123916
Ensembl peptide - ENSMUSP00000136882
NCBI entrez gene - 217826     See in Manteia.
MGI - MGI:2384976
RefSeq - NM_001164427
RefSeq - NM_001164426
RefSeq - NM_146037
RefSeq Peptide - NP_001157898
RefSeq Peptide - NP_001157899
RefSeq Peptide - NP_666149
swissprot - Q3TYG8
swissprot - Q8R1P5
Ensembl - ENSMUSG00000045404
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnk13aENSDARG00000008212Danio rerio
 kcnk13bENSDARG00000043557Danio rerio
 KCNK13ENSGALG00000010672Gallus gallus
 KCNK13ENSG00000152315Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kcnk12 / potassium two pore domain channel subfamily K member 12 / Q9HB15*ENSMUSG0000005013861


Protein motifs (from Interpro)
Interpro ID Name
 IPR003280  Two pore domain potassium channel
 IPR005410  Two pore domain potassium channel, THIK
 IPR013099  Potassium channel domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0030322 stabilization of membrane potential IBA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IBA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0022841 potassium ion leak channel activity IBA


Pathways (from Reactome)
Pathway description
Tandem pore domain halothane-inhibited K+ channel (THIK)
Phase 4 - resting membrane potential


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000136 abnormal microglial cell morphology "anomalous structure, number, or composition of the small neuroglial cells, possibly of mesodermal origin, which may become phagocytic, in areas of neural damage or inflammation" [ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator, J:71688]
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Allelic Composition: Specc1lGt(RRH048)Byg/Specc1l+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003691 abnormal microglial cell function "anomalous activity of the small neuroglial cells, possibly of mesodermal origin, which may become phagocytic, in areas of neural damage or inflammation" [hdene:Howard Dene , Mouse Genome Informatics Curator]
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Allelic Composition: Specc1lGt(RRH048)Byg/Specc1l+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000045404 Kcnk13 / Q8R1P5 / Potassium channel subfamily K member 13 / Q9HB14* / potassium two pore domain channel subfamily K member 13*  / complex






 

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