ENSMUSG00000047298


Mus musculus

Features
Gene ID: ENSMUSG00000047298
  
Biological name :Kcnv2
  
Synonyms : Kcnv2 / Potassium voltage-gated channel subfamily V member 2 / Q8CFS6
  
Possible biological names infered from orthology : potassium voltage-gated channel modifier subfamily V member 2 / Q8TDN2
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: C1
Gene start: 27322588
Gene end: 27337179
  
Corresponding Affymetrix probe sets: 10462303 (MoGene1.0st)   1440537_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000055091
NCBI entrez gene - 240595     See in Manteia.
MGI - MGI:2670981
RefSeq - NM_183179
RefSeq - XM_006527067
RefSeq Peptide - NP_899002
swissprot - Q8CFS6
Ensembl - ENSMUSG00000047298
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnv2aENSDARG00000076644Danio rerio
 KCNV2ENSGALG00000010173Gallus gallus
 KCNV2ENSG00000168263Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kcnb2 / A6H8H5 / Potassium voltage-gated channel subfamily B member 2 / Q92953*ENSMUSG0000009208333
Kcnb1 / Q03717 / Potassium voltage-gated channel subfamily B member 1 / Q14721*ENSMUSG0000005055632
Kcnv1 / Q8BZN2 / Potassium voltage-gated channel subfamily V member 1 / Q6PIU1* / potassium voltage-gated channel modifier subfamily V member 1*ENSMUSG0000002234231
Kcns1 / O35173 / Potassium voltage-gated channel subfamily S member 1 / Q96KK3* / potassium voltage-gated channel modifier subfamily S member 1*ENSMUSG0000004016430
Kcns3 / Q8BQZ8 / Potassium voltage-gated channel subfamily S member 3 / Q9BQ31* / potassium voltage-gated channel modifier subfamily S member 3*ENSMUSG0000004367330
Kcns2 / O35174 / Potassium voltage-gated channel subfamily S member 2 / Q9ULS6* / potassium voltage-gated channel modifier subfamily S member 2*ENSMUSG0000005096328
Kcng4 / Q80XM3 / Potassium voltage-gated channel subfamily G member 4 / Q8TDN1* / potassium voltage-gated channel modifier subfamily G member 4*ENSMUSG0000004524627
Kcnf1 / potassium voltage-gated channel modifier subfamily F member 1 / Q9H3M0*ENSMUSG0000005172627
Kcng1 / A2BDX4 / Potassium voltage-gated channel subfamily G member 1 / Q9UIX4* / potassium voltage-gated channel modifier subfamily G member 1*ENSMUSG0000007457527
Kcng3 / P59053 / Potassium voltage-gated channel subfamily G member 3 / Q8TAE7* / potassium voltage-gated channel modifier subfamily G member 3*ENSMUSG0000004505323
Kcng2 / potassium voltage-gated channel modifier subfamily G member 2 / Q9UJ96*ENSMUSG0000005985223


Protein motifs (from Interpro)
Interpro ID Name
 IPR003131  Potassium channel tetramerisation-type BTB domain
 IPR003968  Potassium channel, voltage dependent, Kv
 IPR003971  Potassium channel, voltage dependent, Kv9
 IPR005821  Ion transport domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR028325  Voltage-gated potassium channel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IBA
 molecular_functionGO:0005267 potassium channel activity IEA


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000160 kyphosis "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: Izumo1rtm1b(KOMP)Wtsi/Izumo1rtm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Izumo1rtm1b(KOMP)Wtsi/Rbrc

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gt(ROSA)26Sortm2(ITK/Syk)Hjum/Gt(ROSA)26Sor+,Tg(Lck-cre)I57Jxm/0
Genetic Background: involves: 129S6/SvEvTac * ICR

 MP:0010092 increased circulating magnesium level "an elevation in the blood concentration of magnesium" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Izumo1rtm1b(KOMP)Wtsi/Izumo1rtm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Izumo1rtm1b(KOMP)Wtsi/Rbrc

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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