ENSMUSG00000050963


Mus musculus

Features
Gene ID: ENSMUSG00000050963
  
Biological name :Kcns2
  
Synonyms : Kcns2 / O35174 / Potassium voltage-gated channel subfamily S member 2
  
Possible biological names infered from orthology : potassium voltage-gated channel modifier subfamily S member 2 / Q9ULS6
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: B3.1
Gene start: 34837355
Gene end: 34843407
  
Corresponding Affymetrix probe sets: 10423647 (MoGene1.0st)   1421342_at (Mouse Genome 430 2.0 Array)   1457325_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000072645
Ensembl peptide - ENSMUSP00000153984
NCBI entrez gene - 16539     See in Manteia.
MGI - MGI:1197011
RefSeq - NM_001271704
RefSeq - NM_181317
RefSeq Peptide - NP_001258633
RefSeq Peptide - NP_851834
swissprot - O35174
Ensembl - ENSMUSG00000050963
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KCNS2ENSGALG00000043764Gallus gallus
 KCNS2ENSG00000156486Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kcns3 / Q8BQZ8 / Potassium voltage-gated channel subfamily S member 3 / Q9BQ31* / potassium voltage-gated channel modifier subfamily S member 3*ENSMUSG0000004367353
Kcns1 / O35173 / Potassium voltage-gated channel subfamily S member 1 / Q96KK3* / potassium voltage-gated channel modifier subfamily S member 1*ENSMUSG0000004016451
Kcnv1 / Q8BZN2 / Potassium voltage-gated channel subfamily V member 1 / Q6PIU1* / potassium voltage-gated channel modifier subfamily V member 1*ENSMUSG0000002234242
Kcnb2 / A6H8H5 / Potassium voltage-gated channel subfamily B member 2 / Q92953*ENSMUSG0000009208340
Kcnb1 / Q03717 / Potassium voltage-gated channel subfamily B member 1 / Q14721*ENSMUSG0000005055639
Kcnv2 / Q8CFS6 / Potassium voltage-gated channel subfamily V member 2 / Q8TDN2* / potassium voltage-gated channel modifier subfamily V member 2*ENSMUSG0000004729834
Kcnf1 / potassium voltage-gated channel modifier subfamily F member 1 / Q9H3M0*ENSMUSG0000005172634
Kcng1 / A2BDX4 / Potassium voltage-gated channel subfamily G member 1 / Q9UIX4* / potassium voltage-gated channel modifier subfamily G member 1*ENSMUSG0000007457534
Kcng4 / Q80XM3 / Potassium voltage-gated channel subfamily G member 4 / Q8TDN1* / potassium voltage-gated channel modifier subfamily G member 4*ENSMUSG0000004524632
Kcng2 / potassium voltage-gated channel modifier subfamily G member 2 / Q9UJ96*ENSMUSG0000005985229
Kcng3 / P59053 / Potassium voltage-gated channel subfamily G member 3 / Q8TAE7* / potassium voltage-gated channel modifier subfamily G member 3*ENSMUSG0000004505328


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR003131  Potassium channel tetramerisation-type BTB domain
 IPR003968  Potassium channel, voltage dependent, Kv
 IPR003971  Potassium channel, voltage dependent, Kv9
 IPR005821  Ion transport domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR028325  Voltage-gated potassium channel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 biological_processGO:1902259 regulation of delayed rectifier potassium channel activity IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IEA
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Kltm1Lex/Kltm1Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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