ENSMUSG00000047428


Mus musculus

Features
Gene ID: ENSMUSG00000047428
  
Biological name :Dlk2
  
Synonyms : 2 / Dlk2 / Q8K1E3
  
Possible biological names infered from orthology : delta like non-canonical Notch ligand 2 / Q6UY11
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: C
Gene start: 46297421
Gene end: 46303271
  
Corresponding Affymetrix probe sets: 10445514 (MoGene1.0st)   1420807_a_at (Mouse Genome 430 2.0 Array)   1450005_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000132349
Ensembl peptide - ENSMUSP00000141164
Ensembl peptide - ENSMUSP00000058470
Ensembl peptide - ENSMUSP00000126993
Ensembl peptide - ENSMUSP00000128897
NCBI entrez gene - 106565     See in Manteia.
MGI - MGI:2146838
RefSeq - XM_006523389
RefSeq - XM_006523388
RefSeq - NM_001286013
RefSeq - NM_001286028
RefSeq - XM_011246235
RefSeq Peptide - NP_001272957
RefSeq Peptide - NP_001272942
swissprot - Q8K1E3
swissprot - E9Q0Y2
swissprot - A0A087WSS3
Ensembl - ENSMUSG00000047428
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dlk2ENSDARG00000076247Danio rerio
 DLK2ENSGALG00000010386Gallus gallus
 DLK2ENSG00000171462Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dlk1 / delta like non-canonical Notch ligand 1 / P80370*ENSMUSG0000004085634
2 / Crb2 / Q80YA8 / Q5IJ48* / crumbs 2, cell polarity complex component*ENSMUSG0000003540332
1 / Crb1 / Q8VHS2 / P82279* / crumbs 1, cell polarity complex component*ENSMUSG0000006368130
Slit1 / Q80TR4 / Slit homolog 1 protein / O75093* / slit guidance ligand 1*ENSMUSG0000002502027
Slit2 / Q9R1B9 / slit guidance ligand 2 / O94813*ENSMUSG0000003155826
Slit3 / Q9WVB4 / Slit homolog 3 protein / O75094* / slit guidance ligand 3*ENSMUSG0000005642726
Dner / Q8JZM4 / Delta and Notch-like epidermal growth factor-related receptor / Q8NFT8* / delta/notch like EGF repeat containing*ENSMUSG0000003676622
Dll3 / O88516 / Delta-like protein 3 / Q9NYJ7* / delta like canonical Notch ligand 3*ENSMUSG0000000343617


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045598 regulation of fat cell differentiation IDA
 biological_processGO:0045746 negative regulation of Notch signaling pathway ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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