ENSMUSG00000047604


Mus musculus

Features
Gene ID: ENSMUSG00000047604
  
Biological name :Frat2
  
Synonyms : Frat2 / GSK-3-binding protein FRAT2 / Q8K025
  
Possible biological names infered from orthology : FRAT2, WNT signaling pathway regulator / O75474
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: C3
Gene start: 41845972
Gene end: 41848132
  
Corresponding Affymetrix probe sets: 10467650 (MoGene1.0st)   1455220_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000052788
NCBI entrez gene - 212398     See in Manteia.
MGI - MGI:2673967
RefSeq - NM_177603
RefSeq Peptide - NP_808271
swissprot - Q8K025
Ensembl - ENSMUSG00000047604
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FRAT2ENSG00000181274Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Frat1 / P70339 / Proto-onco FRAT1 / Q92837* / FRAT1, WNT signaling pathway regulator*ENSMUSG0000006719975
Peg12 / FRAT1* / Q92837* / FRAT1, WNT signaling pathway regulator*ENSMUSG0000007052670


Protein motifs (from Interpro)
Interpro ID Name
 IPR008014  Glycogen synthase kinase-3 binding protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016055 Wnt signaling pathway IGI
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Beta-catenin phosphorylation cascade
Disassembly of the destruction complex and recruitment of AXIN to the membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Nfibtm1Rmg/Nfib+
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Frat1tm1Brn/Frat1tm1Brn,Frat2tm2Brn/Frat2tm2Brn,Peg12tm1Brn/Peg12tm1Brn
Genetic Background: involves: 129P2/OlaHsd * FVB

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000022812 Gsk3b / Q9WV60 / glycogen synthase kinase 3 beta / P49841*  / complex / reaction






 

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