ENSMUSG00000070526


Mus musculus

Features
Gene ID: ENSMUSG00000070526
  
Biological name :Peg12
  
Synonyms : Peg12
  
Possible biological names infered from orthology : FRAT1 / FRAT1, WNT signaling pathway regulator / Q92837
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: C
Gene start: 62461871
Gene end: 62464510
  
Corresponding Affymetrix probe sets: 10564266 (MoGene1.0st)   1420406_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000091897
NCBI entrez gene - 27412     See in Manteia.
MGI - MGI:1351637
RefSeq - NM_013788
RefSeq Peptide - NP_038816
swissprot - Q9WVA7
Ensembl - ENSMUSG00000070526
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FRAT1ENSG00000165879Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Frat1 / P70339 / Proto-onco FRAT1 / Q92837* / FRAT1, WNT signaling pathway regulator*ENSMUSG0000006719977
Frat2 / Q8K025 / GSK-3-binding protein FRAT2 / O75474* / FRAT2, WNT signaling pathway regulator*ENSMUSG0000004760457


Protein motifs (from Interpro)
Interpro ID Name
 IPR008014  Glycogen synthase kinase-3 binding protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000578 embryonic axis specification IDA


Pathways (from Reactome)
Pathway description
Beta-catenin phosphorylation cascade
Disassembly of the destruction complex and recruitment of AXIN to the membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Nfibtm1Rmg/Nfib+
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Frat1tm1Brn/Frat1tm1Brn,Frat2tm2Brn/Frat2tm2Brn,Peg12tm1Brn/Peg12tm1Brn
Genetic Background: involves: 129P2/OlaHsd * FVB

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000022812 Gsk3b / Q9WV60 / glycogen synthase kinase 3 beta / P49841*  / complex / reaction






 

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