ENSMUSG00000047867


Mus musculus

Features
Gene ID: ENSMUSG00000047867
  
Biological name :Gimap6
  
Synonyms : Gimap6 / GTPase IMAP family member 6 / Q8K349
  
Possible biological names infered from orthology : Q6P9H5
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: B2.3
Gene start: 48701582
Gene end: 48708225
  
Corresponding Affymetrix probe sets: 10544583 (MoGene1.0st)   1427891_at (Mouse Genome 430 2.0 Array)   1456762_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000059371
Ensembl peptide - ENSMUSP00000145325
Ensembl peptide - ENSMUSP00000113918
NCBI entrez gene - 231931     See in Manteia.
MGI - MGI:1918876
RefSeq - NM_153175
RefSeq Peptide - NP_694815
swissprot - D3Z3H3
swissprot - A0A0N4SW08
swissprot - Q8K349
Ensembl - ENSMUSG00000047867
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AL953865.1ENSDARG00000109438Danio rerio
 BX004816.1ENSDARG00000040497Danio rerio
 BX569789.1ENSDARG00000099678Danio rerio
 CABZ01049362.1ENSDARG00000099508Danio rerio
 CABZ01059407.1ENSDARG00000115164Danio rerio
 CABZ01059408.1ENSDARG00000116928Danio rerio
 CR388047.1ENSDARG00000090015Danio rerio
 CR774195.1ENSDARG00000078832Danio rerio
 FO680692.1ENSDARG00000109228Danio rerio
 FP326649.2ENSDARG00000117179Danio rerio
 LO018551.1ENSDARG00000115941Danio rerio
 LO018605.1ENSDARG00000093082Danio rerio
 si:ch1073-185p12.2ENSDARG00000100199Danio rerio
 si:ch1073-322p19.1ENSDARG00000075173Danio rerio
 si:ch211-113e8.5ENSDARG00000069707Danio rerio
 si:ch211-113e8.6ENSDARG00000074610Danio rerio
 si:ch211-229i14.2ENSDARG00000086048Danio rerio
 si:ch73-285p12.4ENSDARG00000054548Danio rerio
 si:ch73-308m11.1ENSDARG00000039752Danio rerio
 si:dkey-125e8.4ENSDARG00000041333Danio rerio
 si:dkey-1c7.3ENSDARG00000074205Danio rerio
 si:dkey-73p2.1ENSDARG00000095739Danio rerio
 si:dkey-73p2.2ENSDARG00000079245Danio rerio
 si:dkey-73p2.3ENSDARG00000095076Danio rerio
 si:dkey-88j15.3ENSDARG00000076573Danio rerio
 si:dkey-88j15.4ENSDARG00000079471Danio rerio
 si:dkeyp-52c3.5ENSDARG00000038392Danio rerio
 si:dkeyp-67a8.4ENSDARG00000090099Danio rerio
 si:dkeyp-67a8.4ENSDARG00000092823Danio rerio
 zgc:113625ENSDARG00000054160Danio rerio
 zgc:152658ENSDARG00000018587Danio rerio
 zgc:153642ENSDARG00000052900Danio rerio
 zgc:171452ENSDARG00000074069Danio rerio
 zgc:172091ENSDARG00000103058Danio rerio
 zgc:194443ENSDARG00000078182Danio rerio
 ENSGALG00000029857Gallus gallus
 GIMAP6ENSG00000133561Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q99MI6 / Gimap3 / GTPase IMAP family member 3 / GIMAP5* / Q96F15* / GIMAP1-GIMAP5* / GIMAP1-GIMAP5 readthrough* / GTPase, IMAP family member 5*ENSMUSG0000003926432
Gimap5 / Q8BWF2 / GTPase IMAP family member 5 / Q96F15* / GIMAP1-GIMAP5* / GIMAP1-GIMAP5 readthrough*ENSMUSG0000004350532
Gimap1 / GTPase, IMAP family member 1 / Q8WWP7*ENSMUSG0000009001930
Gimap9 / GIMAP7* / Q8NHV1* / GTPase, IMAP family member 7*ENSMUSG0000005112427
Gimap4 / Q99JY3 / GTPase IMAP family member 4 / Q9NUV9*ENSMUSG0000005443527
Gimap8 / Q75N62 / GTPase IMAP family member 8 / Q8ND71*ENSMUSG0000006426227
Gimap7 / Q8NHV1* / GTPase, IMAP family member 7*ENSMUSG0000004393125


Protein motifs (from Interpro)
Interpro ID Name
 IPR006703  AIG1-type guanine nucleotide-binding (G) domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000194 hypercalcemia "abnormally high concentration of calcium ions in the circulating blood " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Foxo3tm1.1(KOMP)Vlcg/Foxo3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Foxo3tm1.1(KOMP)Vlcg/J

 MP:0000220 increased monocyte count "greater than normal monocyte numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

 MP:0001556 increased circulating HDL cholesterol level "higher than average level of high density lipoprotein in the blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47439]
Show

Allelic Composition: Foxo3tm1.1(KOMP)Vlcg/Foxo3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Foxo3tm1.1(KOMP)Vlcg/J

 MP:0002591 decreased mean corpuscular volume "less than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Foxo3tm1.1(KOMP)Vlcg/Foxo3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Foxo3tm1.1(KOMP)Vlcg/J

 MP:0002833 increased heart weight "greater than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Foxo3tm1.1(KOMP)Vlcg/Foxo3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Foxo3tm1.1(KOMP)Vlcg/J

 MP:0003131 increased erythrocyte count "greater number of the cells in the blood that carry oxygen, red blood cells, per unit" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Foxo3tm1.1(KOMP)Vlcg/Foxo3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Foxo3tm1.1(KOMP)Vlcg/J

 MP:0005018 decreased T cell number "fewer than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

 MP:0005178 increased total circulating cholesterol level "greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Foxo3tm1.1(KOMP)Vlcg/Foxo3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Foxo3tm1.1(KOMP)Vlcg/J

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Foxo3tm1.1(KOMP)Vlcg/Foxo3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Foxo3tm1.1(KOMP)Vlcg/J

 MP:0005562 decreased mean corpuscular hemoglobin "less than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Foxo3tm1.1(KOMP)Vlcg/Foxo3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Foxo3tm1.1(KOMP)Vlcg/J

 MP:0005565 increased blood urea nitrogen level "high circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Foxo3tm1.1(KOMP)Vlcg/Foxo3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Foxo3tm1.1(KOMP)Vlcg/J

 MP:0008040 decreased NK T cell number "reduced number of the distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repertoire of variable region gene segments" [GO:0001865]
Show

Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

 MP:0008079 decreased CD8-positive T cell number "reduction in the number of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

 MP:0008805 decreased circulating amylase level "reduction in the concentration of a group of amylolytic enzymes that cleave starch, glycogen, and related alpha-1,4-glucans in the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:D08.811.277.450.066, MGI:brs "Beverly Richards-Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Foxo3tm1.1(KOMP)Vlcg/Foxo3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Foxo3tm1.1(KOMP)Vlcg/J

 MP:0010169 decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number "a reduction in the number of the CD4-positive, CD25-positive T cell subset which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release" [ISBN:0781735149]
Show

Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

 MP:0012765 decreased alpha-beta T cell number "reduced number of T cells that expresses an alpha-beta T cell receptor complex" [CL:0000789]
Show

Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

 MP:0012767 increased KLRG1-positive NK cell number "increase in the number of KLRG1 positive NK cells that represent a maturation subset of NK cells and is linked to NK cell proliferation" [MGI:Annie_Speak, PMID:19479342]
Show

Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

 MP:0013279 increased fasted circulating glucose level "increase in the amount of glucose in the blood at some defined time point after eating compared to controls" [MGI:Armida_Di_Fenza]
Show

Allelic Composition: Foxo3tm1.1(KOMP)Vlcg/Foxo3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Foxo3tm1.1(KOMP)Vlcg/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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