ENSMUSG00000050799


Mus musculus

Features
Gene ID: ENSMUSG00000050799
  
Biological name :Hist1h2ba
  
Synonyms : Hist1h2ba / Histone H2B type 1-A / P70696
  
Possible biological names infered from orthology : histone cluster 1 H2B family member a / Q96A08
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: A3.1
Gene start: 23933773
Gene end: 23934156
  
Corresponding Affymetrix probe sets: 10408266 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000056604
NCBI entrez gene - 319177     See in Manteia.
MGI - MGI:2448375
RefSeq - NM_175663
RefSeq Peptide - NP_783594
swissprot - P70696
Ensembl - ENSMUSG00000050799
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6PC60ENSDARG00000068996Danio rerio
 P0C1H3ENSGALG00000039722Gallus gallus
 P0C1H3ENSGALG00000037934Gallus gallus
 P0C1H3ENSGALG00000027571Gallus gallus
 P0C1H3ENSGALG00000042263Gallus gallus
 P0C1H3ENSGALG00000027594Gallus gallus
 P0C1H5ENSGALG00000036908Gallus gallus
 Q96A08ENSG00000146047Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6ZWY9 / Hist1h2bc / Histone H2B type 1-C/E/G ENSMUSG0000001810287
Q6ZWY9 / Hist1h2be / Histone H2B type 1-C/E/G / P62807* / HIST1H2BC* / histone cluster 1 H2B family member c*ENSMUSG0000004724687
Q6ZWY9 / Hist1h2bg / Histone H2B type 1-C/E/G ENSMUSG0000005838587
Q8CGP1 / Hist1h2bk / Histone H2B type 1-K / H2BFS* / O60814* / P57053* / H2B histone family member S* / histone cluster 1 H2B family member k*ENSMUSG0000006272787
P10853 / Hist1h2bf / Histone H2B type 1-F/J/L ENSMUSG0000006926887
P10853 / Hist1h2bj / Histone H2B type 1-F/J/L ENSMUSG0000006930087
P10853 / Hist1h2br / Histone H2B type 1-F/J/L ENSMUSG0000006930387
P10853 / Hist1h2bq / Histone H2B type 1-F/J/L ENSMUSG0000006930787
Q8CGP2 / Hist1h2bp / Histone H2B type 1-P ENSMUSG0000006930887
P10853 / Hist1h2bl / Histone H2B type 1-F/J/L ENSMUSG0000009433887
P10853 / Hist1h2bn / Histone H2B type 1-F/J/L ENSMUSG0000009521787
P10854 / Hist1h2bm / Histone H2B type 1-M / P58876* / HIST1H2BD* / histone cluster 1 H2B family member d*ENSMUSG0000011427987
Q64524 / Hist2h2be / Histone H2B type 2-E / P06899* / HIST1H2BJ* / histone cluster 1 H2B family member j*ENSMUSG0000006885486
Q64475 / Hist1h2bb / Histone H2B type 1-B / Q99879* / HIST1H2BM* / histone cluster 1 H2B family member m*ENSMUSG0000007503186
Q64525 / Hist2h2bb / Histone H2B type 2-B / Q5QNW6* / HIST2H2BF* / histone cluster 2 H2B family member f*ENSMUSG0000010582786
Q64478 / Hist1h2bh / Histone H2B type 1-H ENSMUSG0000011445686
Q9D2U9 / Hist3h2ba / Histone H2B type 3-A ENSMUSG0000005689585
H2bfm / P0C1H6* / H2BFWT* / Q7Z2G1* / H2B histone family member M* / H2B histone family member W, testis specific*ENSMUSG0000004815551
Q9D9Z7 / 1700024P04Rik / RIKEN cDNA 1700024P04 geneENSMUSG0000004502241


Protein motifs (from Interpro)
Interpro ID Name
 IPR000558  Histone H2B
 IPR007125  Histone H2A/H2B/H3
 IPR009072  Histone-fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IDA
 biological_processGO:0006334 nucleosome assembly IEA
 biological_processGO:0006337 nucleosome disassembly IMP
 biological_processGO:0006954 inflammatory response IMP
 biological_processGO:0031639 plasminogen activation IMP
 biological_processGO:0035093 spermatogenesis, exchange of chromosomal proteins IMP
 biological_processGO:0051099 positive regulation of binding IMP
 biological_processGO:0071674 mononuclear cell migration IMP
 cellular_componentGO:0000786 nucleosome ISO
 cellular_componentGO:0000788 nuclear nucleosome IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0019897 extrinsic component of plasma membrane IDA
 molecular_functionGO:0003677 DNA binding IBA
 molecular_functionGO:0042393 histone binding IPI
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Packaging Of Telomere Ends
Formation of the beta-catenin:TCF transactivating complex
PRC2 methylates histones and DNA
Condensation of Prophase Chromosomes
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
DNA Damage/Telomere Stress Induced Senescence
HDACs deacetylate histones
HATs acetylate histones
SIRT1 negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
Transcriptional regulation by small RNAs
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Deposition of new CENPA-containing nucleosomes at the centromere
G2/M DNA damage checkpoint
RNA Polymerase I Promoter Opening
RNA Polymerase I Chain Elongation
E3 ubiquitin ligases ubiquitinate target proteins
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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