MP:0000188 | abnormal circulating glucose level | "anomalous concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Cacna1ctm3Hfm/Cacna1ctm4Hfm,A1cfTg(Myh6-cre/Esr1*)1Jmk/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
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MP:0001547 | abnormal lipid level | "anomalous concentrations of fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water) in the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Hbegftm2Mek/Hbegftm2Mek Genetic Background: B6.Cg-Hbegftm2Mek
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MP:0001554 | increased circulating free fatty acid level | "higher than normal levels of unesterified fatty acids in the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:65146] |
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Allelic Composition: Cacna1ctm3Hfm/Cacna1ctm4Hfm,A1cfTg(Myh6-cre/Esr1*)1Jmk/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
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MP:0002310 | resistance to fatty liver development | "less likely than the norm to to develop hepatic steatosis " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Cacna1ctm3Hfm/Cacna1ctm4Hfm,A1cfTg(Myh6-cre/Esr1*)1Jmk/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
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MP:0002446 | abnormal macrophage morphology | "anomalous structure, number, or composition of the large mononuclear phagocytic cells found in most tissues of the body" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Hbegftm2Mek/Hbegftm2Mek Genetic Background: B6.Cg-Hbegftm2Mek
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MP:0002451 | abnormal macrophage physiology | "abnormal function or response of the phagocytic leukocytes involved in innate immunity, early non-adaptive phases of host-defense, antigen presentation, and which act as effector cells in humoral and cell-mediated immunity" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Hbegftm2Mek/Hbegftm2Mek Genetic Background: B6.Cg-Hbegftm2Mek
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MP:0002644 | decreased circulating triglyceride level | "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Cacna1ctm3Hfm/Cacna1ctm4Hfm,A1cfTg(Myh6-cre/Esr1*)1Jmk/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
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MP:0002891 | increased insulin sensitivity | "greater ability to clear glucose from the bloodstream when given insulin than normal; can result in hypoglycemia" [RGD:Rat Genome Database submission] |
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Allelic Composition: Cacna1ctm3Hfm/Cacna1ctm4Hfm,A1cfTg(Myh6-cre/Esr1*)1Jmk/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
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MP:0005292 | improved glucose tolerance | "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Cacna1ctm3Hfm/Cacna1ctm4Hfm,A1cfTg(Myh6-cre/Esr1*)1Jmk/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
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MP:0005416 | abnormal circulating protein level | "anomalous blood concentration of any of the macromolecules consisting of long chains of amino acids in peptide linkage" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Hbegftm2Mek/Hbegftm2Mek Genetic Background: B6.Cg-Hbegftm2Mek
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MP:0005584 | abnormal enzyme/coenzyme activity | "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Samd8tm2.2Kwi/Samd8tm2.2Kwi Genetic Background: involves: 129P2/OlaHsd
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MP:0005621 | abnormal cell physiology | "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator] |
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Allelic Composition: Hbegftm2Mek/Hbegftm2Mek Genetic Background: B6.Cg-Hbegftm2Mek
Allelic Composition: Sgms2tm1Kenw/Sgms2tm1Kenw Genetic Background: B6.129S2-Sgms2tm1Kenw
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MP:0005659 | resistance to diet-induced obesity | "less likely to become excessively fat or to increase fat in the subcutaneous connective tissue as a result of consuming a diet geared to increase body fat " [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator] |
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Allelic Composition: Sgms2tm1Kenw/Sgms2tm1Kenw Genetic Background: B6.129S2-Sgms2tm1Kenw
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MP:0009289 | decreased epididymal fat pad weight | |
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Allelic Composition: Sgms2tm1Kenw/Sgms2tm1Kenw Genetic Background: B6.129S2-Sgms2tm1Kenw
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MP:0009823 | abnormal sphingomyelin level | "deviation in the expected amount of any of a group of phospholipids that are found especially in, but not restricted to, nerve tissue and yield sphingosine, choline, a fatty acid, and phosphoric acid upon hydrolysis" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hbegftm2Mek/Hbegftm2Mek Genetic Background: B6.Cg-Hbegftm2Mek
Allelic Composition: Sgms2tm1Jia/Sgms2tm1Jia Genetic Background: Not Specified
Allelic Composition: Samd8tm1Jia/Samd8tm1Jia,Sgms2tm1Jia/Sgms2tm1Jia Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Samd8tm1.1Kwi/Samd8tm1.1Kwi,Sgms2tm1Jia/Sgms2tm1Jia Genetic Background: involves: 129P2/OlaHsd
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MP:0010080 | abnormal hepatocyte physiology | "any functional anomaly of the main structural specialized epithelial cells which normally organize into interconnected plates called lobules" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hbegftm2Mek/Hbegftm2Mek Genetic Background: B6.Cg-Hbegftm2Mek
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MP:0010163 | hemolysis | "destruction of erythrocytes such that hemoglobin is released from the cells; may occur by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Hbegftm2Mek/Hbegftm2Mek Genetic Background: B6.Cg-Hbegftm2Mek
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MP:0012232 | abnormal ceramide level | |
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Allelic Composition: Sgms2tm1Jia/Sgms2tm1Jia Genetic Background: Not Specified
Allelic Composition: Samd8tm1Jia/Samd8tm1Jia,Sgms2tm1Jia/Sgms2tm1Jia Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Samd8tm1.1Kwi/Samd8tm1.1Kwi,Sgms2tm1Jia/Sgms2tm1Jia Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Samd8tm2.2Kwi/Samd8tm2.2Kwi,Sgms2tm1Jia/Sgms2tm1Jia Genetic Background: involves: 129P2/OlaHsd
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