ENSMUSG00000056155


Mus musculus

Features
Gene ID: ENSMUSG00000056155
  
Biological name :Nanos3
  
Synonyms : Mus musculus nanos C2HC-type zinc finger 3 (Nanos3), transcript variant 2, mRNA. / Nanos3 / P60324
  
Possible biological names infered from orthology : nanos C2HC-type zinc finger 3 / P60323
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: C2
Gene start: 84173731
Gene end: 84185217
  
Corresponding Affymetrix probe sets: 10580131 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000067385
Ensembl peptide - ENSMUSP00000147775
NCBI entrez gene - 244551     See in Manteia.
MGI - MGI:2675387
RefSeq - XM_006530981
RefSeq - NM_001357361
RefSeq - NM_194059
RefSeq Peptide - NP_918948
RefSeq Peptide - NP_001344290
swissprot - P60324
swissprot - Q0VDU5
Ensembl - ENSMUSG00000056155
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nanos3ENSDARG00000068255Danio rerio
 NANOS3ENSG00000187556Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nanos2 / P60322 / Nanos homolog 2 / P60321* / nanos C2HC-type zinc finger 2*ENSMUSG0000005196531
Nanos1 / Q80WY3 / Nanos homolog 1 / Q8WY41* / nanos C2HC-type zinc finger 1*ENSMUSG0000007243726


Protein motifs (from Interpro)
Interpro ID Name
 IPR008705  Nanos/Xcat2
 IPR024161  Zinc finger, nanos-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007281 germ cell development IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0017148 negative regulation of translation IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0048477 oogenesis IMP
 biological_processGO:0051726 regulation of cell cycle IDA
 biological_processGO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IEA
 biological_processGO:2001234 negative regulation of apoptotic signaling pathway IMP
 cellular_componentGO:0000932 P-body IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0010494 cytoplasmic stress granule IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001116 small gonad "reduced size of the testis or the ovary" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Ubr2tm1Ytkw/Ubr2tm1Ytkw
Genetic Background: involves: 129S1/Sv

 MP:0001127 small ovary "reduced size of the female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
Show

Allelic Composition: Ubr2tm1Ytkw/Ubr2tm1Ytkw
Genetic Background: involves: 129S1/Sv

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Ubr2tm1Ytkw/Ubr2tm1Ytkw
Genetic Background: involves: 129S1/Sv

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Ubr2tm1Ytkw/Ubr2tm1Ytkw
Genetic Background: involves: 129S1/Sv

 MP:0004806 absent germ cells "absence of germ cells, that is, any of the reproductive (generative) cells of a multicellular organism, whether they are undifferentiated or fully differentiated" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Ubr2tm1Ytkw/Ubr2tm1Ytkw
Genetic Background: involves: 129S1/Sv

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ubr2tm1Ytkw/Ubr2tm1Ytkw
Genetic Background: involves: 129S1/Sv

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ubr2tm1Ytkw/Ubr2tm1Ytkw
Genetic Background: involves: 129S1/Sv

 MP:0005168 abnormal female meiosis "malfunction in the process of nuclear division that results in ova with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Baxtm1Sjk/Baxtm1Sjk,Nanos2tm1Ysa/Nanos2tm1Ysa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0006361 abnormal female germ cell morphology "any structural anomaly female germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Baxtm1Sjk/Baxtm1Sjk,Nanos2tm1Ysa/Nanos2tm1Ysa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0008392 decreased primordial germ cell number "reduced number of a mesodermally-derived, most primitive undifferentiated sex cell, that originates in the allantois and migrates through the hindgut and into the gonadal ridge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ubr2tm1Ytkw/Ubr2tm1Ytkw
Genetic Background: involves: 129S1/Sv

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr