ENSMUSG00000056673


Mus musculus

Features
Gene ID: ENSMUSG00000056673
  
Biological name :Kdm5d
  
Synonyms : Kdm5d / Lysine-specific demethylase 5D / Q62240
  
Possible biological names infered from orthology : lysine demethylase 5D / Q9BY66
  
Species: Mus musculus
  
Chr. number: Y
Strand: 1
Band: A1
Gene start: 897788
Gene end: 956786
  
Corresponding Affymetrix probe sets: 10607972 (MoGene1.0st)   1424903_at (Mouse Genome 430 2.0 Array)   1452562_at (Mouse Genome 430 2.0 Array)   1452563_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000061095
Ensembl peptide - ENSMUSP00000139636
Ensembl peptide - ENSMUSP00000140462
Ensembl peptide - ENSMUSP00000140663
NCBI entrez gene - 20592     See in Manteia.
MGI - MGI:99780
RefSeq - XM_017318684
RefSeq - NM_011419
RefSeq - XM_006531578
RefSeq - XM_011248580
RefSeq Peptide - NP_035549
swissprot - Q8BQM3
swissprot - A0A087WR43
swissprot - Q62240
Ensembl - ENSMUSG00000056673
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kdm5cENSDARG00000006124Danio rerio
 KDM5DENSG00000012817Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kdm5c / P41230 / Lysine-specific demethylase 5C / P41229* / lysine demethylase 5C*ENSMUSG0000002533278
Kdm5a / Q3UXZ9 / Lysine-specific demethylase 5A / P29375* / lysine demethylase 5A*ENSMUSG0000003018050
Kdm5b / Q80Y84 / Lysine-specific demethylase 5B / Q9UGL1* / lysine demethylase 5B*ENSMUSG0000004220744
Jarid2 / Q62315 / Protein Jumonji / Q92833* / jumonji and AT-rich interaction domain containing 2*ENSMUSG0000003851812


Protein motifs (from Interpro)
Interpro ID Name
 IPR001606  ARID DNA-binding domain
 IPR001965  Zinc finger, PHD-type
 IPR003347  JmjC domain
 IPR003349  JmjN domain
 IPR004198  Zinc finger, C5HC2-type
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013637  Lysine-specific demethylase-like domain
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger
 IPR036431  ARID DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002457 T cell antigen processing and presentation IDA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0034720 histone H3-K4 demethylation ISO
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0060765 regulation of androgen receptor signaling pathway ISO
 cellular_componentGO:0001650 fibrillar center ISO
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0032453 histone demethylase activity (H3-K4 specific) ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050681 androgen receptor binding ISO
 molecular_functionGO:0051213 dioxygenase activity IEA


Pathways (from Reactome)
Pathway description
HDMs demethylate histones


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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