ENSMUSG00000058427


Mus musculus

Features
Gene ID: ENSMUSG00000058427
  
Biological name :Cxcl2
  
Synonyms : Cxcl2 / C-X-C motif chemokine 2 / P10889
  
Possible biological names infered from orthology : CXCL1 / CXCL3 / C-X-C motif chemokine ligand 1 / C-X-C motif chemokine ligand 2 / C-X-C motif chemokine ligand 3 / P09341 / P19875 / P19876
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: E1
Gene start: 90903871
Gene end: 90905938
  
Corresponding Affymetrix probe sets: 10523156 (MoGene1.0st)   1449984_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000074885
Ensembl peptide - ENSMUSP00000144334
NCBI entrez gene - 20310     See in Manteia.
MGI - MGI:1340094
RefSeq - NM_009140
RefSeq Peptide - NP_033166
swissprot - P10889
swissprot - Q3U1J5
swissprot - Q3U1L9
Ensembl - ENSMUSG00000058427
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CXCL1ENSG00000163739Homo sapiens
 CXCL2ENSG00000081041Homo sapiens
 CXCL3ENSG00000163734Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cxcl3 / Q6W5C0 / C-X-C motif chemokine 3 / CXCL1* / CXCL2* / P09341* / P19875* / P19876* / C-X-C motif chemokine ligand 3* / C-X-C motif chemokine ligand 2* / C-X-C motif chemokine ligand 1*ENSMUSG0000002937982
Cxcl1 / P12850 / Growth-regulated alpha protein KC(5-72) / CXCL3* / CXCL2* / P19876* / P09341* / P19875* / C-X-C motif chemokine ligand 2* / C-X-C motif chemokine ligand 1* / C-X-C motif ch...ENSMUSG0000002938064
Cxcl5 / P50228 / C-X-C motif chemokine 5 GCP-2(1-78) GCP-2(9-78) / CXCL6* / P80162* / P42830* / C-X-C motif chemokine ligand 6* / C-X-C motif chemokine ligand 5*ENSMUSG0000002937144
Ppbp / pro-platelet basic protein / P02775*ENSMUSG0000002937243
Cxcl15 / Q9WVL7 / C-X-C motif chemokine 15 ENSMUSG0000002937529


Protein motifs (from Interpro)
Interpro ID Name
 IPR001089  CXC chemokine
 IPR001811  Chemokine interleukin-8-like domain
 IPR018048  CXC chemokine, conserved site
 IPR033899  CXC Chemokine domain
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001975 response to amphetamine IEA
 biological_processGO:0002237 response to molecule of bacterial origin IDA
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0006952 defense response IEA
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IBA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0009408 response to heat IEA
 biological_processGO:0010332 response to gamma radiation IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030593 neutrophil chemotaxis IEA
 biological_processGO:0030595 leukocyte chemotaxis IEA
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0032496 response to lipopolysaccharide IBA
 biological_processGO:0042060 wound healing IEA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0051384 response to glucocorticoid IEA
 biological_processGO:0060326 cell chemotaxis IEA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0070997 neuron death IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:0071347 cellular response to interleukin-1 IEA
 biological_processGO:0090023 positive regulation of neutrophil chemotaxis IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005623 cell IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0008009 chemokine activity IBA
 molecular_functionGO:0045236 CXCR chemokine receptor binding IBA


Pathways (from Reactome)
Pathway description
Chemokine receptors bind chemokines
G alpha (i) signalling events
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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