ENSMUSG00000059547


Mus musculus

Features
Gene ID: ENSMUSG00000059547
  
Biological name :Fbxw26
  
Synonyms : Fbxw26
  
Possible biological names infered from orthology : F-box and WD repeat domain containing 12 / FBXW12 / Q6X9E4
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: F2
Gene start: 109717566
Gene end: 109746089
  
Corresponding Affymetrix probe sets: 10597088 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000071811
NCBI entrez gene - 382109     See in Manteia.
MGI - MGI:3646662
RefSeq - NM_198674
RefSeq Peptide - NP_941076
swissprot - Q8BI58
Ensembl - ENSMUSG00000059547
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch73-142c19.1ENSDARG00000058871Danio rerio
 FBXW12ENSG00000164049Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fbxw16 / FBXW12* / Q6X9E4* / F-box and WD repeat domain containing 12*ENSMUSG0000007406282
Fbxw22 / FBXW12* / Q6X9E4* / F-box and WD repeat domain containing 12*ENSMUSG0000007032479
Fbxw19 / FBXW12* / Q6X9E4* / F-box and WD repeat domain containing 12*ENSMUSG0000007406179
Fbxw20 / FBXW12* / Q6X9E4* / F-box and WD repeat domain containing 12*ENSMUSG0000006170177
Fbxw14 / FBXW12* / Q6X9E4* / F-box and WD repeat domain containing 12*ENSMUSG0000010558976
Fbxw28 / FBXW12* / Q6X9E4* / F-box and WD repeat domain containing 12*ENSMUSG0000005408775
Fbxw25 / FBXW12* / Q6X9E4* / F-box and WD repeat domain containing 12*ENSMUSG0000009499275
Fbxw24 / FBXW12* / Q6X9E4* / F-box and WD repeat domain containing 12*ENSMUSG0000006227574
Fbxw18 / FBXW12* / Q6X9E4* / F-box and WD repeat domain containing 12*ENSMUSG0000007405974
Fbxw21 / FBXW12* / Q6X9E4* / F-box and WD repeat domain containing 12*ENSMUSG0000004723772
Fbxw13 / FBXW12* / Q6X9E4* / F-box and WD repeat domain containing 12*ENSMUSG0000004931469
Fbxw15 / L7N1X6 / F-box/WD repeat-containing protein 15 / FBXW12* / Q6X9E4* / F-box and WD repeat domain containing 12*ENSMUSG0000007406069
Fbxw27 / F-box and WD-40 domain protein 27 isoform 1 / FBXW12* / Q6X9E4* / F-box and WD repeat domain containing 12*ENSMUSG0000010461433
Fbxw17ENSMUSG0000003781631


Protein motifs (from Interpro)
Interpro ID Name
 IPR001810  F-box domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR036047  F-box-like domain superfamily
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002493 increased IgG "greater than normal immunoglobulin class G level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Faddtm1e.1(KOMP)Wtsi/Faddtm1e.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Faddtm1e.1(KOMP)Wtsi/Ucd

 MP:0005628 decreased circulating potassium level "less than the normal concentration in the blood of this alkaline metallic element, the most abundant intracellular ion; anomalies in the extracellular (circulating) concentration have important implications for the function of excitable tissues, such as nerve and muscle" [RGD:Rat Genome Database submission]
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Allelic Composition: Faddtm1e.1(KOMP)Wtsi/Faddtm1e.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Faddtm1e.1(KOMP)Wtsi/Ucd

 MP:0008044 increased NK cell number "greater number of non-T, non-B lymphocytes, having a granular morphology and which are important in innate immunity to viruses and other intracellular pathogens; in addition, these cells can kill certain tumor cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease"]
Show

Allelic Composition: Faddtm1e.1(KOMP)Wtsi/Faddtm1e.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Faddtm1e.1(KOMP)Wtsi/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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