ENSMUSG00000059991


Mus musculus

Features
Gene ID: ENSMUSG00000059991
  
Biological name :Nptx2
  
Synonyms : Neuronal pentraxin-2 / Nptx2 / O70340
  
Possible biological names infered from orthology : P47972
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: G2
Gene start: 144545902
Gene end: 144557478
  
Corresponding Affymetrix probe sets: 10527332 (MoGene1.0st)   1420720_at (Mouse Genome 430 2.0 Array)   1449960_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000071687
NCBI entrez gene - 53324     See in Manteia.
MGI - MGI:1858209
RefSeq - NM_016789
RefSeq Peptide - NP_058069
swissprot - O70340
Ensembl - ENSMUSG00000059991
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nptx2aENSDARG00000037794Danio rerio
 nptx2bENSDARG00000045164Danio rerio
 NPTX2ENSGALG00000003562Gallus gallus
 NPTX2ENSG00000106236Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nptx1 / Q62443 / neuronal pentraxin 1 / Q15818*ENSMUSG0000002558255
Nptxr / neuronal pentraxin receptor / O95502*ENSMUSG0000002242149
Npcd / NPTXR* / O95502* / neuronal pentraxin receptor*ENSMUSG0000008983740
Ptx4 / pentraxin-4 isoform 2 / Q96A99* / pentraxin 4*ENSMUSG0000004417226
Ptx3 / P48759 / Pentraxin-related protein PTX3 / P26022* / pentraxin 3*ENSMUSG0000002783219
Apcs / P12246 / serum amyloid P-component / P02743* / amyloid P component, serum*ENSMUSG0000002654214
Mptx1ENSMUSG0000002653113
Mptx2 / mucosal pentraxin 2ENSMUSG0000007918013
Crp / P14847 / C-reactive protein / P02741*ENSMUSG0000003794212


Protein motifs (from Interpro)
Interpro ID Name
 IPR001759  Pentraxin-related
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR030476  Pentaxin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008306 associative learning IMP
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002184 abnormal innervation "the malformation, misprojection or malfunction of the connection of nerve fibers with a target" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Nme1tm1Jyd/Nme1tm1Jyd
Genetic Background: 129-Nme1tm1Jyd

Allelic Composition: Nptx1tm1Mspn/Nptx1tm1Mspn,Nptx2tm1Mspn/Nptx2tm1Mspn,Nptxrtm1Mspn/Nptxrtm1Mspn
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Nptx2tm1Mspn/Nptx2tm1Mspn
Genetic Background: involves: 129 * C57BL/6

 MP:0002802 abnormal discrimination learning "defects in the ability to exhibit a differential response to different stimuli that is achieved by the reinforcement of the desired response for each particular stimulus" [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Gprc5atm1Rlo/Gprc5a+
Genetic Background: involves: 129 * C57BL/6

 MP:0005551 abnormal eye electrophysiology "abnormal function of the eye as determined through electrophysiological recordings from single cells or summary recordings from multiple cells (e.g. electroretinogram)" [NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
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Allelic Composition: Nptx1tm1Mspn/Nptx1tm1Mspn,Nptx2tm1Mspn/Nptx2tm1Mspn
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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