ENSMUSG00000062751


Mus musculus

Features
Gene ID: ENSMUSG00000062751
  
Biological name :Prss1
  
Synonyms : Prss1
  
Possible biological names infered from orthology : P07477 / P07478 / P35030 / PRSS2 / PRSS3 / serine protease 1 / serine protease 2 / serine protease 3
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: B1
Gene start: 41458932
Gene end: 41463786
  
Corresponding Affymetrix probe sets: 10537650 (MoGene1.0st)   10544342 (MoGene1.0st)   1422682_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031910
NCBI entrez gene - 114228     See in Manteia.
MGI - MGI:98839
RefSeq - NM_053243
RefSeq Peptide - NP_444473
swissprot - Q9Z1R9
Ensembl - ENSMUSG00000062751
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prss1ENSDARG00000042993Danio rerio
 ENSGALG00000040609Gallus gallus
 ENSGALG00000030650Gallus gallus
 ENSGALG00000027291Gallus gallus
 PRSS2ENSGALG00000032796Gallus gallus
 PRSS1ENSG00000204983Homo sapiens
 PRSS2ENSG00000275896Homo sapiens
 PRSS3ENSG00000010438Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm5771 / PRSS1* / PRSS2* / PRSS3* / P07477* / P07478* / P35030* / serine protease 2* / serine protease 3* / serine protease 1*ENSMUSG0000005811998
Gm10334 / PRSS1* / PRSS2* / PRSS3* / P07477* / P07478* / P35030* / serine protease 2* / serine protease 3* / serine protease 1*ENSMUSG0000007151798
Prss3 / PRSS2* / PRSS1* / P07478* / P07477* / P35030* / serine protease 3* / serine protease 1* / serine protease 2*ENSMUSG0000007151997
Try5 / PRSS2* / PRSS3* / PRSS1* / P07477* / P35030* / P07478* / serine protease 2* / serine protease 3* / serine protease 1*ENSMUSG0000003693893
Try4 / trypsin 4 / PRSS3* / PRSS1* / PRSS2* / P35030* / P07478* / P07477* / serine protease 3* / serine protease 1* / serine protease 2*ENSMUSG0000005410693
Try10 / trypsin 10 / PRSS3* / PRSS1* / PRSS2* / P35030* / P07478* / P07477* / serine protease 3* / serine protease 1* / serine protease 2*ENSMUSG0000007152193
Prss2 / P07146 / protease, serine 2 / PRSS1* / PRSS3* / P07478* / P07477* / P35030* / serine protease 3* / serine protease 1* / serine protease 2*ENSMUSG0000005716389
2210010C04Rik / RIKEN cDNA 2210010C04 geneENSMUSG0000002988277
Gm2663ENSMUSG0000009652570
1810009J06Rik / RIKEN cDNA 1810009J06 geneENSMUSG0000009480869
Klk14 / Q8CGR5 / Kallikrein-14 / Q9P0G3* / kallikrein related peptidase 14*ENSMUSG0000004473747
Klk13 / kallikrein related-peptidase 13 / Q9UKR3*ENSMUSG0000005404646
Klk11 / Q9QYN3 / Kallikrein-11 / Q9UBX7* / kallikrein related peptidase 11*ENSMUSG0000006761646
Klk9 / Q9UKQ9* / AC011473.4* / kallikrein related peptidase 9*ENSMUSG0000004788445
Klk15 / kallikrein related peptidase 15 / Q9H2R5*ENSMUSG0000005519345
Klk8 / Q61955 / Kallikrein-8 / O60259* / kallikrein related peptidase 8*ENSMUSG0000006402343
Klk6 / kallikrein related peptidase 6 / Q92876*ENSMUSG0000005006342
Gm4744ENSMUSG0000006325240


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IBA
 biological_processGO:0007586 digestion IBA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0004252 serine-type endopeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Activation of Matrix Metalloproteinases
Cobalamin (Cbl, vitamin B12) transport and metabolism
Neutrophil degranulation
Antimicrobial peptides


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000274 enlarged heart "increase over normal size of the heart" [J:29971]
Show

Allelic Composition: Ppp3r2tm1.1(KOMP)Vlcg/Ppp3r2tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Ppp3r2tm1.1(KOMP)Vlcg/Ucd

 MP:0002059 abnormal seminal gland morphology "anomalous structure of one of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ppp3r2tm1.1(KOMP)Vlcg/Ppp3r2tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Ppp3r2tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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