ENSMUSG00000063428


Mus musculus

Features
Gene ID: ENSMUSG00000063428
  
Biological name :Ddo
  
Synonyms : D-aspartate oxidase / Ddo / Q922Z0
  
Possible biological names infered from orthology : Q99489
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: B1
Gene start: 40630011
Gene end: 40681847
  
Corresponding Affymetrix probe sets: 10362701 (MoGene1.0st)   1439096_at (Mouse Genome 430 2.0 Array)   1451650_at (Mouse Genome 430 2.0 Array)   1453499_at (Mouse Genome 430 2.0 Array)   1454025_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000150979
Ensembl peptide - ENSMUSP00000150785
Ensembl peptide - ENSMUSP00000151066
Ensembl peptide - ENSMUSP00000019977
Ensembl peptide - ENSMUSP00000149767
Ensembl peptide - ENSMUSP00000149768
NCBI entrez gene - 70503     See in Manteia.
MGI - MGI:1925528
RefSeq - XM_006512848
RefSeq - NM_001316716
RefSeq - NM_001316717
RefSeq - NM_001316718
RefSeq - NM_001316719
RefSeq - NM_027442
RefSeq - XM_006512842
RefSeq - XM_006512843
RefSeq - XM_006512846
RefSeq Peptide - NP_001303647
RefSeq Peptide - NP_001303648
RefSeq Peptide - NP_081718
RefSeq Peptide - NP_001303645
RefSeq Peptide - NP_001303646
swissprot - Q3TNE8
swissprot - Q922Z0
swissprot - Q9D2B4
swissprot - A0A1L1SS55
swissprot - A0A1L1SS65
swissprot - Q2UVA9
Ensembl - ENSMUSG00000063428
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:172341ENSDARG00000079664Danio rerio
 DDOENSGALG00000015057Gallus gallus
 DDOENSG00000203797Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dao / D-amino acid oxidase / P14920*ENSMUSG0000004209641


Protein motifs (from Interpro)
Interpro ID Name
 IPR006076  FAD dependent oxidoreductase
 IPR006181  D-amino acid oxidase, conserved site
 IPR023209  D-amino-acid oxidase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006531 aspartate metabolic process IMP
 biological_processGO:0006533 aspartate catabolic process ISO
 biological_processGO:0007320 insemination IMP
 biological_processGO:0007625 grooming behavior IMP
 biological_processGO:0019478 D-amino acid catabolic process IDA
 biological_processGO:0042445 hormone metabolic process IMP
 biological_processGO:0046416 D-amino acid metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003884 D-amino-acid oxidase activity IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0008445 D-aspartate oxidase activity ISO
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0048037 cofactor binding IEA
 molecular_functionGO:0071949 FAD binding IEA


Pathways (from Reactome)
Pathway description
Glyoxylate metabolism and glycine degradation
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
Show

Allelic Composition: Runx1tm1.1Medv/Runx1tm1.1Medv
Genetic Background: involves: 129P2/OlaHsd

 MP:0001377 abnormal copulation "reduced or absent attempt of sexual contact between a male and a receptive female " [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Runx1tm1.1Medv/Runx1tm1.1Medv
Genetic Background: involves: 129P2/OlaHsd

 MP:0001442 decreased grooming behavior "reduced amount of time spent cleaning and/or keeping outward appearance tidy (self, mate or offspring)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Runx1tm1.1Medv/Runx1tm1.1Medv
Genetic Background: involves: 129P2/OlaHsd

 MP:0005332 abnormal amino acid level "aberrant concentration of these organic compounds, which, when polymerized, form proteins" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Runx1tm1.1Medv/Runx1tm1.1Medv
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Ddotm1Rdl/Ddotm1Rdl
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0005646 abnormal pituitary gland physiology "anmalous function of this unpaired compound gland suspended from the base of the hypothalamus by a short extension of the infundibulum, the infundibular or pituitary stalk" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Runx1tm1.1Medv/Runx1tm1.1Medv
Genetic Background: involves: 129P2/OlaHsd

 MP:0009856 failure of ejaculation "inability to propulse semen from the genital ducts and the urethra to the exterior within a defined test period" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Runx1tm1.1Medv/Runx1tm1.1Medv
Genetic Background: involves: 129P2/OlaHsd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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