ENSMUSG00000042096


Mus musculus

Features
Gene ID: ENSMUSG00000042096
  
Biological name :Dao
  
Synonyms : D-amino acid oxidase / Dao
  
Possible biological names infered from orthology : P14920
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: F
Gene start: 114003703
Gene end: 114025682
  
Corresponding Affymetrix probe sets: 10524422 (MoGene1.0st)   1420709_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000143337
Ensembl peptide - ENSMUSP00000083792
Ensembl peptide - ENSMUSP00000107911
Ensembl peptide - ENSMUSP00000125588
NCBI entrez gene - 13142     See in Manteia.
MGI - MGI:94859
RefSeq - XM_006530162
RefSeq - NM_001286396
RefSeq - NM_001286397
RefSeq - NM_010018
RefSeq - XM_006530161
RefSeq Peptide - NP_001273325
RefSeq Peptide - NP_001273326
RefSeq Peptide - NP_034148
swissprot - A0A0R4J203
swissprot - Q91WH3
swissprot - A0A0G2JFX0
Ensembl - ENSMUSG00000042096
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dao.1ENSDARG00000035602Danio rerio
 dao.2ENSDARG00000035603Danio rerio
 dao.3ENSDARG00000035601Danio rerio
 DAOENSGALG00000043053Gallus gallus
 DAOENSG00000110887Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ddo / Q922Z0 / D-aspartate oxidase / Q99489*ENSMUSG0000006342840


Protein motifs (from Interpro)
Interpro ID Name
 IPR006076  FAD dependent oxidoreductase
 IPR006181  D-amino acid oxidase, conserved site
 IPR023209  D-amino-acid oxidase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006562 proline catabolic process IEA
 biological_processGO:0036088 D-serine catabolic process IEA
 biological_processGO:0042416 dopamine biosynthetic process IEA
 biological_processGO:0046416 D-amino acid metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0055130 D-alanine catabolic process IEA
 biological_processGO:0070178 D-serine metabolic process IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0005778 peroxisomal membrane IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003884 D-amino-acid oxidase activity IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA
 molecular_functionGO:0048037 cofactor binding IEA
 molecular_functionGO:0071949 FAD binding IEA


Pathways (from Reactome)
Pathway description
Glyoxylate metabolism and glycine degradation
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001363 increased anxiety-related response "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060]
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Allelic Composition: Enamtm1.1Jcch/Enamtm1.1Jcch
Genetic Background: involves: C57BL/6

 MP:0001393 ataxia "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]
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Allelic Composition: Drd5tm1Sib/Drd5tm1Sib
Genetic Background: B6.129S4-Drd5tm1Sib

 MP:0001408 stereotypic behavior "repetitive, invariant, perseverative motor patterns that do not appear to be purposeful" [What s wrong with my mouse?:ISBN 0-471-31639-3]
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Allelic Composition: Drd5tm1Sib/Drd5tm1Sib
Genetic Background: B6.129S4-Drd5tm1Sib

 MP:0002204 abnormal neurotransmitter physiology "aberrant function or production of endogenous signaling molecules secreted by neurons that alter the behavior of neurons or effector cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Drd5tm1Sib/Drd5tm1Sib
Genetic Background: B6.129S4-Drd5tm1Sib

 MP:0005311 abnormal circulating amino acid level "aberrant concentration in the blood of these organic compounds, which, when polymerized, form proteins" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:83263]
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Allelic Composition: Drd5tm1Sib/Drd5tm1Sib
Genetic Background: B6.129S4-Drd5tm1Sib

Allelic Composition: Daotm1Ttsu/Daotm1Ttsu
Genetic Background: 129S/SvEv-Daotm1Ttsu

 MP:0005332 abnormal amino acid level "aberrant concentration of these organic compounds, which, when polymerized, form proteins" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Daotm1Ttsu/Daotm1Ttsu
Genetic Background: 129S/SvEv-Daotm1Ttsu

 MP:0009747 impaired behavioral response to xenobiotic "decreased sensitivity to a foreign compound capable of inducing the appearance of behavioral response, such as consumption preference, induced hyperactivity or stereotypic behavior, or increased dosage threshold for the appearance of the behavioral response" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Drd5tm1Sib/Drd5tm1Sib
Genetic Background: B6.129S4-Drd5tm1Sib

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000042096 Dao / D-amino acid oxidase / P14920*  / complex






 

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