ENSMUSG00000073433


Mus musculus

Features
Gene ID: ENSMUSG00000073433
  
Biological name :Arhgdig
  
Synonyms : Arhgdig / Q62160 / Rho GDP-dissociation inhibitor 3
  
Possible biological names infered from orthology : Q99819 / Rho GDP dissociation inhibitor gamma
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: A3.3
Gene start: 26196226
Gene end: 26207786
  
Corresponding Affymetrix probe sets: 10449245 (MoGene1.0st)   10449258 (MoGene1.0st)   1428952_at (Mouse Genome 430 2.0 Array)   1448660_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000135717
Ensembl peptide - ENSMUSP00000025019
Ensembl peptide - ENSMUSP00000113186
NCBI entrez gene - 14570     See in Manteia.
MGI - MGI:108430
RefSeq - NM_008113
RefSeq Peptide - NP_032139
swissprot - D3Z6W0
swissprot - Q3UNB6
swissprot - Q62160
Ensembl - ENSMUSG00000073433
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARHGDIGENSGALG00000036819Gallus gallus
 Q99819ENSG00000242173Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q61599 / Arhgdib / Rho GDP-dissociation inhibitor 2 / P52566* / Rho GDP dissociation inhibitor beta*ENSMUSG0000003022051
Q99PT1 / Arhgdia / Rho GDP-dissociation inhibitor 1 / P52565* / Rho GDP dissociation inhibitor alpha*ENSMUSG0000002513248


Protein motifs (from Interpro)
Interpro ID Name
 IPR000406  Rho protein GDP-dissociation inhibitor
 IPR014756  Immunoglobulin E-set
 IPR024792  Rho GDP-dissociation inhibitor domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032880 regulation of protein localization IDA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0050790 regulation of catalytic activity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IDA
 molecular_functionGO:0005092 GDP-dissociation inhibitor activity IDA
 molecular_functionGO:0005094 Rho GDP-dissociation inhibitor activity IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030695 GTPase regulator activity IDA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Srftm1Rjs/Srftm2.1Nor,Tg(Myh6-cre)2182Mds/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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