ENSMUSG00000074115


Mus musculus

Features
Gene ID: ENSMUSG00000074115
  
Biological name :Saa1
  
Synonyms : P05366 / Saa1 / serum amyloid A 1
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: B3
Gene start: 46740497
Gene end: 46742980
  
Corresponding Affymetrix probe sets: 10563611 (MoGene1.0st)   1419075_s_at (Mouse Genome 430 2.0 Array)   1450788_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000119150
NCBI entrez gene - 20208     See in Manteia.
MGI - MGI:98221
RefSeq - XM_006540726
RefSeq - NM_001357493
RefSeq - NM_009117
RefSeq - XM_006540724
RefSeq - XM_006540725
RefSeq Peptide - NP_001344422
RefSeq Peptide - NP_033143
swissprot - Q5I0U6
swissprot - P05366
Ensembl - ENSMUSG00000074115
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 saaENSDARG00000045999Danio rerio
 ENSGALG00000027716Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Saa2 / P05367 / Mus musculus serum amyloid A 2 (Saa2), transcript variant 2, mRNA.ENSMUSG0000005746593
Saa3 / P04918 / Serum amyloid A-3 protein ENSMUSG0000004002664
Saa4 / P31532 / Serum amyloid A-4 protein / P35542* / serum amyloid A4, constitutive*ENSMUSG0000004001754


Protein motifs (from Interpro)
Interpro ID Name
 IPR000096  Serum amyloid A protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006953 acute-phase response IEA
 biological_processGO:0008203 cholesterol metabolic process IDA
 biological_processGO:0050918 positive chemotaxis IEA
 biological_processGO:0060326 cell chemotaxis IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005881 cytoplasmic microtubule ISO
 cellular_componentGO:0034364 high-density lipoprotein particle IEA
 molecular_functionGO:0001664 G-protein coupled receptor binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0042056 chemoattractant activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003980 increased circulating phospholipid level "greater concentration in the blood of the fat derivatives in which one fatty acid has been replaced by a phosphate group" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ass1bar/Ass1fold
Genetic Background: involves: C57BL/6Ei * C57BL/6J * OF1 * P/J

 MP:0005178 increased total circulating cholesterol level "greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ass1bar/Ass1fold
Genetic Background: involves: C57BL/6Ei * C57BL/6J * OF1 * P/J

 MP:0005278 abnormal cholesterol homeostasis "anomaly in the state of equilibrium in the body of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:71350]
Show

Allelic Composition: Ass1bar/Ass1fold
Genetic Background: involves: C57BL/6Ei * C57BL/6J * OF1 * P/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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