MP:0000371 | diluted coat color | "a coat color that appears lighter in intensity or paler than normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Hps6ru/Hps6ru,Lystbg-slt/Lystbg-slt Genetic Background: involves: YZ57/Ch
Allelic Composition: Hps6ru-7J/Hps6ru-7J Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Hps6ru-Btlr/Hps6ru-Btlr Genetic Background: C57BL/6J-Hps6ru-Btlr
Allelic Composition: Hps6ru-6J/Hps6ru-6J Genetic Background: involves: C3H/HeJ
Allelic Composition: Hps6ru-8J/Hps6ru-8J Genetic Background: B6(CB17)-Hps6ru-8J/J
Allelic Composition: a/a,Hps6ru/Hps6ru Genetic Background: Not Specified
Allelic Composition: a/a,Hps6ru-5J/Hps6ru-5J,Lystbg/Lystbg Genetic Background: involves: C3H/Rl * C57BL/6J
Allelic Composition: Hps6ru-3J/Hps6ru-3J Genetic Background: C57BL/6J-Hps6ru-3J
Allelic Composition: Hps6ru-4J/Hps6ru-4J Genetic Background: SSL/LeJ
Allelic Composition: A/A,Hps6ru/Hps6ru Genetic Background: Not Specified
Allelic Composition: a/a,Mregdsu/Mregdsu,Hps6ru/Hps6ru Genetic Background: involves: C57BL/6J
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MP:0001324 | abnormal eye pigmentation | "change in the normal black pigmentation of the eye to another color, or lack of color" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: a/a,Hps6ru/Hps6ru Genetic Background: Not Specified
Allelic Composition: a/a,Hps6ru-5J/Hps6ru-5J,Lystbg/Lystbg Genetic Background: involves: C3H/Rl * C57BL/6J
Allelic Composition: Hps6ru-3J/Hps6ru-3J Genetic Background: C57BL/6J-Hps6ru-3J
Allelic Composition: Hps6ru-4J/Hps6ru-4J Genetic Background: SSL/LeJ
Allelic Composition: a/a,Hps6ru/Hps6ru Genetic Background: involves: C57BL/6J
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MP:0002075 | abnormal coat color | "irregular or unusual pigmentation pattern of the hair in relation to control animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Tg(Myh6-Tnnt2*)1Feah/0,Tnnt2tm1Feah/Tnnt2+ Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * FVB/N
Allelic Composition: a/a,Hps6ru-5J/Hps6ru-5J,Lystbg/Lystbg Genetic Background: involves: C3H/Rl * C57BL/6J
Allelic Composition: Hps6ru-3J/Hps6ru-3J Genetic Background: C57BL/6J-Hps6ru-3J
Allelic Composition: Hps6ru-4J/Hps6ru-4J Genetic Background: SSL/LeJ
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MP:0002136 | abnormal kidney physiology | "altered ability or inability to excrete urine, not due to anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: a/a,Hps6ru/Hps6ru Genetic Background: B6.Cg-Hps6ru
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MP:0003171 | phenotypic reversion | "reverse mutation to wild-type phenotype from a previously characterized mutant phenotype" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: a/a,Mregdsu/Mregdsu,Hps6ru/Hps6ru Genetic Background: involves: C57BL/6J
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MP:0004165 | abnormal lateral geniculate nucleus morphology | "any malformation or absence of the group of neurons that serve as the primary processor of visual information received from the retina via the optic tract and send processed information to the visual cortex of the occipital lobe" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: a/a,Hps6ru/Hps6ru Genetic Background: B6.Cg-Hps6ru
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MP:0004725 | decreased platelet serotonin level | "reduced concentration of serotonin in the platelets; this biochemical messenger and regulator, found in the CNS, gastrointestinal tract, and produced by platelets mediates neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: a/a,Hps6ru/Hps6ru Genetic Background: B6.Cg-Hps6ru
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MP:0005075 | abnormal melanosome morphology | "anomalous structure of these tissue-specific cytoplasmic organelles within which melanin pigments are synthesized and stored" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:5346] |
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Allelic Composition: a/a,Hps6ru/Hps6ru Genetic Background: involves: C57BL/6J
Allelic Composition: a/a,Hps6ru/Hps6ru,Lystbg/Lystbg Genetic Background: involves: C3H/Rl * C57BL/6J
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MP:0005077 | abnormal melanogenesis | "failure of or anomaly in the biosynthetic pathway of melanin formation in cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:5346] |
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Allelic Composition: a/a,Hps6ru/Hps6ru Genetic Background: involves: C57BL/6J
Allelic Composition: a/a,Hps6ru/Hps6ru,Lystbg/Lystbg Genetic Background: involves: C3H/Rl * C57BL/6J
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MP:0005100 | abnormal choroid pigmentation | "anomalous coloring of the thin, highly vascularized membrane covering most of the posterior of the eye between the retina and the sclera" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: a/a,Hps6ru/Hps6ru Genetic Background: Not Specified
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MP:0005102 | abnormal iris pigmentation | "anomalous coloring of the adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: a/a,Hps6ru/Hps6ru Genetic Background: Not Specified
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MP:0005172 | lack of eye pigmentation | "visual organs are devoid of coloring pigment in relation to control animals, usually resulting in a red or pink color" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500] |
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Allelic Composition: Hps6ru/Hps6ru,Lystbg-slt/Lystbg-slt Genetic Background: involves: YZ57/Ch
Allelic Composition: Hps6ru-7J/Hps6ru-7J Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Hps6ru-6J/Hps6ru-6J Genetic Background: involves: C3H/HeJ
Allelic Composition: Hps6ru-8J/Hps6ru-8J Genetic Background: B6(CB17)-Hps6ru-8J/J
Allelic Composition: a/a,Hps6ru/Hps6ru Genetic Background: Not Specified
Allelic Composition: a/a,Hps6ru-5J/Hps6ru-5J,Lystbg/Lystbg Genetic Background: involves: C3H/Rl * C57BL/6J
Allelic Composition: Hps6ru-3J/Hps6ru-3J Genetic Background: C57BL/6J-Hps6ru-3J
Allelic Composition: Hps6ru-4J/Hps6ru-4J Genetic Background: SSL/LeJ
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MP:0005341 | decreased susceptibility to atherosclerosis | "less likely than the norm to develop thickening and loss of elasticity of arterial walls, involving lipid deposition and thickening of intimal layers within arteries" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: a/a,Hps6ru/Hps6ru Genetic Background: B6.Cg-Hps6ru
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MP:0005408 | hypopigmentation | "dilution of the pigment in the body" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: a/a,Hps6ru/Hps6ru Genetic Background: Not Specified
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MP:0005606 | increased bleeding time | "greater than the normal duration of blood flow after skin puncture; indicative of platelet and capillary function" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission] |
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Allelic Composition: a/a,Hps6ru/Hps6ru Genetic Background: B6.Cg-Hps6ru
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MP:0008056 | abnormal retinal ganglion cell morphology | "any structural anomaly of ganglion neurons located in the innermost nuclear layer of the retina of that receive visual information from photoreceptors via various intermediate cells such as bipolar cells, amacrine cells, and horizontal cells; axons from these cells form the optic nerve and connect mainly to the lateral geniculate nucleus (LGN) and to the suprachiasmatic nucleus in the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: a/a,Hps6ru/Hps6ru Genetic Background: B6.Cg-Hps6ru
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MP:0008763 | abnormal mast cell degranulation | "abnormalities in the exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell" [GO:0043303, MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+,Tg(Neurog3-cre/Esr1*)1Dam/0 Genetic Background: involves: 129S4/SvJae * C57BL/6 * CBA
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MP:0009448 | decreased platelet ATP level | "reduced concentration of the major energy source adenosine triphosphate produced by dense bodies located in platelets" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: a/a,Hps6ru/Hps6ru Genetic Background: B6.Cg-Hps6ru
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MP:0009557 | decreased platelet ADP level | "reduced concentration of the major energy source adenosine diphosphate produced by dense bodies located in platelets" [MGI:mberry "Melissa Berry, Genetics Resources Curator"] |
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Allelic Composition: a/a,Hps6ru/Hps6ru Genetic Background: B6.Cg-Hps6ru
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MP:0010192 | abnormal retinal melanin granule morphology | "any structural anomaly of the pigment particles in the retina" [ISBN-13:978-1-4051-2034-0 "The Pigmentary System, Second Edition"] |
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Allelic Composition: a/a,Hps6ru/Hps6ru,Lystbg/Lystbg Genetic Background: involves: C3H/Rl * C57BL/6J
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MP:0011279 | decreased ear pigmentation | "visually detectable dilution of pigment present in the outer ear" [MGI:csmith] |
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Allelic Composition: Hps6ru-7J/Hps6ru-7J Genetic Background: involves: 129S4/SvJae * C57BL/6
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MP:0020432 | decreased platelet dense granule number | "decreased number of the electron-dense bodies occurring in blood platelets that store and secrete adenosine nucleotides and serotonin" [orcid.org/0000-0003-4606-0597] |
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Allelic Composition: a/a,Hps6ru/Hps6ru Genetic Background: B6.Cg-Hps6ru
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