Manteia

ENSMUSG00000078763

Mus musculus

Features

Gene ID:	ENSMUSG00000078763

Biological name :	Slfn1

Synonyms :	schlafen 1 / Slfn1

Possible biological names infered from orthology :	Q6IEE8 / Q8IYM2 / schlafen family member 12 / schlafen family member 12 like / SLFN12 / SLFN12L

Species:	Mus musculus

Chr. number:	11
Strand:	1
Band:	C
Gene start:	83116849
Gene end:	83122670

Corresponding Affymetrix probe sets:	10379633 (MoGene1.0st) 1418612_at (Mouse Genome 430 2.0 Array) 1447614_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000047782 NCBI entrez gene - 20555 See in Manteia. MGI - MGI:1313259 RefSeq - NM_011407 RefSeq Peptide - NP_035537 swissprot - Q9Z0I7 Ensembl - ENSMUSG00000078763

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Slfn2 / schlafen 2 / Q6IEE8* / Q8IYM2* / SLFN12* / SLFN12L* / schlafen family member 12* / schlafen family member 12 like*	ENSMUSG00000072620	51
Slfn4 / schlafen 4 / Q6IEE8* / Q8IYM2* / SLFN12* / SLFN12L* / schlafen family member 12* / schlafen family member 12 like*	ENSMUSG00000000204	48
Slfn3 / schlafen 3 / Q6IEE8* / Q8IYM2* / SLFN12* / SLFN12L* / schlafen family member 12* / schlafen family member 12 like*	ENSMUSG00000018986	45
Slfn14 / V9GXG1 / Protein SLFN14 C-terminally truncated SLFN14 endoribonuclease / P0C7P3* / schlafen family member 14*	ENSMUSG00000082101	37
Slfn9 / Q7Z7L1* / SLFN11* / SLFN13* / Q68D06* / schlafen family member 11* / schlafen family member 13*	ENSMUSG00000069793	35
Slfn8 / schlafen 8 / SLFN13* / Q68D06* / Q7Z7L1* / SLFN11* / schlafen family member 13* / schlafen family member 11*	ENSMUSG00000035208	33
Slfn5 / Q8CBA2 / Schlafen family member 5 / Q08AF3*	ENSMUSG00000054404	32

Protein motifs (from Interpro)

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA
biological_process	GO:0001933	negative regulation of protein phosphorylation	IDA
biological_process	GO:0007050	cell cycle arrest	IDA
biological_process	GO:0008285	negative regulation of cell proliferation	IDA
biological_process	GO:0042130	negative regulation of T cell proliferation	IDA
biological_process	GO:1900477	negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter	IDA
biological_process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	IGI
cellular_component	GO:0005634	nucleus	IDA
cellular_component	GO:0005737	cytoplasm	IDA
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0005524	ATP binding	IEA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0002059	abnormal seminal gland morphology	"anomalous structure of one of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Scrib^{tm1b(NCOM)Mfgc}/Scrib^{tm1b(NCOM)Mfgc} Genetic Background: C57BL/6N-Scrib^{tm1a(NCOM)Mfgc}/Tcp
MP:0002169	no phenotype detected	"normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Dlk1^tm1Hsul/Dlk1⁺ Genetic Background: involves: 129 * C57BL/6J

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr