ENSMUSG00000079466


Mus musculus

Features
Gene ID: ENSMUSG00000079466
  
Biological name :Prdm12
  
Synonyms : A2AJ77 / Prdm12 / PR domain zinc finger protein 12
  
Possible biological names infered from orthology : PR/SET domain 12 / Q9H4Q4
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: B
Gene start: 31640037
Gene end: 31655795
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSMUSP00000109098
NCBI entrez gene - 381359     See in Manteia.
MGI - MGI:2685844
RefSeq - NM_001123362
RefSeq - XM_006498161
RefSeq Peptide - NP_001116834
swissprot - A2AJ77
Ensembl - ENSMUSG00000079466
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prdm12bENSDARG00000007430Danio rerio
 PRDM12ENSGALG00000003895Gallus gallus
 PRDM12ENSG00000130711Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
E9Q3T6 / Prdm14 / PR domain containing 14 / Q9GZV8* / PR/SET domain 14*ENSMUSG0000004241428
Prdm6 / Q3UZD5 / Putative histone-lysine N-methyltransferase PRDM6 / Q9NQX0* / PR/SET domain 6*ENSMUSG0000006937828
Prdm4 / Q80V63 / PR domain zinc finger protein 4 / Q9UKN5* / PR/SET domain 4*ENSMUSG0000003552923
Rtcb / Q99LF4 / tRNA-splicing ligase RtcB homolog / Q9Y3I0* / RNA 2,3-cyclic phosphate and 5-OH ligase*ENSMUSG000000017838


Protein motifs (from Interpro)
Interpro ID Name
 IPR001214  SET domain
 IPR013087  Zinc finger C2H2-type
 IPR017126  PR-domain zinc finger protein PRDM12
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0019233 sensory perception of pain ISO
 biological_processGO:0022008 neurogenesis IDA
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0050965 detection of temperature stimulus involved in sensory perception of pain ISO
 biological_processGO:0051574 positive regulation of histone H3-K9 methylation ISO
 biological_processGO:1900111 positive regulation of histone H3-K9 dimethylation ISO
 cellular_componentGO:0005634 nucleus ISO
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:1990226 histone methyltransferase binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
Show

Allelic Composition: Ppargtm1b(KOMP)Wtsi/Ppargtm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Ppargtm1b(KOMP)Wtsi/H

 MP:0001697 abnormal embryo size "anomalous proportions of embryo compared to littermates" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ppargtm1b(KOMP)Wtsi/Ppargtm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Ppargtm1b(KOMP)Wtsi/H

 MP:0002192 hydrops fetalis "an abnormal accumulation of serous fluid in fetal tissues" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ppargtm1b(KOMP)Wtsi/Ppargtm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Ppargtm1b(KOMP)Wtsi/H

 MP:0005178 increased total circulating cholesterol level "greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ppargtm1b(KOMP)Wtsi/Ppargtm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Ppargtm1b(KOMP)Wtsi/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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