ENSMUSG00000091228


Mus musculus

Features
Gene ID: ENSMUSG00000091228
  
Biological name :Gm20390
  
Synonyms : Gm20390
  
Possible biological names infered from orthology : NME1-NME2 / NME1-NME2 readthrough / NME2 / NME/NM23 nucleoside diphosphate kinase 2 / P22392
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: D
Gene start: 93949819
Gene end: 93968293
  
Corresponding Affymetrix probe sets: 10389858 (MoGene1.0st)   10535927 (MoGene1.0st)   1424110_a_at (Mouse Genome 430 2.0 Array)   1448808_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000132590
MGI - MGI:5141855
swissprot - E9PZF0
Ensembl - ENSMUSG00000091228
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nme2aENSDARG00000043820Danio rerio
 nme2b.1ENSDARG00000103791Danio rerio
 nme2b.2ENSDARG00000099420Danio rerio
 NME2ENSGALG00000002932Gallus gallus
 NME1-NME2ENSG00000011052Homo sapiens
 NME2ENSG00000243678Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nme2 / Q01768 / NME/NM23 nucleoside diphosphate kinase 2 / P22392* / NME1-NME2* / NME1-NME2 readthrough*ENSMUSG0000002085757
Nme1 / P15532 / Nucleoside diphosphate kinase A / P15531* / NME/NM23 nucleoside diphosphate kinase 1*ENSMUSG0000003760151
Nme3 / Q9WV85 / Nucleoside diphosphate kinase 3 / Q13232* / NME/NM23 nucleoside diphosphate kinase 3*ENSMUSG0000007343536
Nme4 / Q9WV84 / Nucleoside diphosphate kinase, mitochondrial / O00746* / NME/NM23 nucleoside diphosphate kinase 4*ENSMUSG0000002417731
Nme7 / NME/NM23 family member 7 / Q9Y5B8*ENSMUSG0000002657516
Nme6 / O88425 / Nucleoside diphosphate kinase 6 / O75414* / NME/NM23 nucleoside diphosphate kinase 6*ENSMUSG0000003247815
Nme5 / Q99MH5 / Nucleoside diphosphate kinase homolog 5 / P56597* / NME/NM23 family member 5*ENSMUSG0000003598415
Nme8 / Q715T0 / Thioredoxin domain-containing protein 3 / Q8N427* / NME/NM23 family member 8*ENSMUSG0000004113813
Nme9 / NME/NM23 family member 9 / Q86XW9*ENSMUSG000000462429


Protein motifs (from Interpro)
Interpro ID Name
 IPR001564  Nucleoside diphosphate kinase
 IPR023005  Nucleoside diphosphate kinase, active site
 IPR034907  Nucleoside diphosphate kinase-like domain
 IPR036850  Nucleoside diphosphate kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006165 nucleoside diphosphate phosphorylation IEA
 biological_processGO:0006183 GTP biosynthetic process IEA
 biological_processGO:0006228 UTP biosynthetic process IEA
 biological_processGO:0006241 CTP biosynthetic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0042981 regulation of apoptotic process IBA
 cellular_componentGO:0005622 intracellular IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004550 nucleoside diphosphate kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000037601 Nme1 / P15532 / Nucleoside diphosphate kinase A / P15531* / NME/NM23 nucleoside diphosphate kinase 1*  / complex
 ENSMUSG00000020857 Nme2 / Q01768 / NME/NM23 nucleoside diphosphate kinase 2 / P22392* / NME1-NME2* / NME1-NME2 readthrough*  / complex
 ENSMUSG00000091228 Gm20390 / NME2* / P22392* / NME1-NME2* / NME1-NME2 readthrough* / NME/NM23 nucleoside diphosphate kinase 2*  / complex






 

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