ENSMUSG00000091387


Mus musculus

Features
Gene ID: ENSMUSG00000091387
  
Biological name :Gcnt4
  
Synonyms : Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 / E9Q649 / Gcnt4
  
Possible biological names infered from orthology : glucosaminyl (N-acetyl) transferase 4, core 2 / Q9P109
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: D1
Gene start: 96924689
Gene end: 96950906
  
Corresponding Affymetrix probe sets: 10406777 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000130496
NCBI entrez gene - 218476     See in Manteia.
MGI - MGI:2684919
RefSeq - XM_006517601
RefSeq - NM_001166065
RefSeq - XM_006517599
RefSeq - XM_006517600
RefSeq - XM_006517596
RefSeq - XM_006517597
RefSeq - XM_006517598
RefSeq Peptide - NP_001159537
swissprot - E9Q649
Ensembl - ENSMUSG00000091387
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gcnt4aENSDARG00000035198Danio rerio
 gcnt4bENSDARG00000077550Danio rerio
 si:dkeyp-87d8.8ENSDARG00000044755Danio rerio
 GCNT4ENSGALG00000014944Gallus gallus
 GCNT4ENSG00000176928Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gcnt3 / Q5JCT0 / Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 / O95395* / glucosaminyl (N-acetyl) transferase 3, mucin type*ENSMUSG0000003222638
Gcnt1 / Q09324 / Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase / Q02742* / glucosaminyl (N-acetyl) transferase 1, core 2*ENSMUSG0000003884337
Gcnt2 / P97402 / N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase / Q8N0V5* / glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)*ENSMUSG0000002136034
Gcnt7 / Q3V3K7 / Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7 / Q6ZNI0* / glucosaminyl (N-acetyl) transferase family member 7*ENSMUSG0000007456926
Xylt2 / Q9EPL0 / xylosyltransferase II / Q9H1B5* / xylosyltransferase 2*ENSMUSG0000002086818
Xylt1 / xylosyltransferase 1 / Q86Y38*ENSMUSG0000003065718


Protein motifs (from Interpro)
Interpro ID Name
 IPR003406  Glycosyl transferase, family 14


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002121 inter-male aggressive behavior IMP
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0042403 thyroid hormone metabolic process IMP
 biological_processGO:0048729 tissue morphogenesis IMP
 biological_processGO:0048872 homeostasis of number of cells IMP
 biological_processGO:0060993 kidney morphogenesis IGI
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity IEA
 molecular_functionGO:0008375 acetylglucosaminyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA


Pathways (from Reactome)
Pathway description
O-linked glycosylation of mucins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000219 increased neutrophil count "greater than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Dkc1tm2Pjma/Y
Genetic Background: chimera involves: 129X1/SvJ * C57BL/6J

 MP:0000511 abnormal intestinal mucosa morphology "structural or developmental anomalies of the mucous lining of the intestine; this consists of epithelium, lamina, propria, and a layer of smooth muscle cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Dkc1tm2Pjma/Y
Genetic Background: chimera involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Gcnt1tm1Jxm/Gcnt1tm1Jxm,Gcnt3tm1.1Jxm/Gcnt3tm1.1Jxm,Gcnt4tm1.1Jxm/Gcnt4tm1.1Jxm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001354 increased aggression towards males "when compared to controls, subjects exhibit greater than the normal level of domineering, assaultive posture and/or hostile physical action toward male mice" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Webster s II New College Dictionary:ISBN 0-395-70869-9]
Show

Allelic Composition: Dkc1tm2Pjma/Y
Genetic Background: chimera involves: 129X1/SvJ * C57BL/6J

 MP:0002135 abnormal kidney morphology "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Dkc1tm2Pjma/Y
Genetic Background: chimera involves: 129X1/SvJ * C57BL/6J

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Dkc1tm2Pjma/Y
Genetic Background: chimera involves: 129X1/SvJ * C57BL/6J

 MP:0005478 decreased circulating thyroxine level "less than the normal blood concentration of the major hormone dervied from the thryoid gland; it normally affects cellular metabolism" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Dkc1tm2Pjma/Y
Genetic Background: chimera involves: 129X1/SvJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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