ENSMUSG00000095498


Mus musculus

Features
Gene ID: ENSMUSG00000095498
  
Biological name :Ifna1
  
Synonyms : Ifna1 / Interferon alpha-1 / P01572
  
Possible biological names infered from orthology : IFNA10 / IFNA13 / IFNA14 / IFNA16 / IFNA17 / IFNA2 / IFNA21 / IFNA4 / IFNA5 / IFNA6 / IFNA7 / IFNA8 / interferon alpha 10 / interferon alpha 13 / interferon alpha 14 / interferon alpha 16 / interferon alpha 17 / interferon alpha 2 / interferon alpha 21 / interferon alpha 4 / interferon alpha 5 / interferon alpha 6 / interferon alpha 7 / interferon alpha 8 / P01562 / P01563 / P01566 / P01567 / P01568 / P01569 / P01570 / P01571 / P05013 / P05014 / P05015 / P32881
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: C4
Gene start: 88850087
Gene end: 88850656
  
Corresponding Affymetrix probe sets: 10505879 (MoGene1.0st)   10505892 (MoGene1.0st)   1450564_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000092580
NCBI entrez gene - 15962     See in Manteia.
MGI - MGI:107668
RefSeq - NM_010502
RefSeq Peptide - NP_034632
swissprot - P01572
Ensembl - ENSMUSG00000095498
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000015062Gallus gallus
 IFNA1ENSG00000197919Homo sapiens
 IFNA10ENSG00000186803Homo sapiens
 IFNA13ENSG00000233816Homo sapiens
 IFNA14ENSG00000228083Homo sapiens
 IFNA16ENSG00000147885Homo sapiens
 IFNA17ENSG00000234829Homo sapiens
 IFNA2ENSG00000188379Homo sapiens
 IFNA21ENSG00000137080Homo sapiens
 IFNA4ENSG00000236637Homo sapiens
 IFNA5ENSG00000147873Homo sapiens
 IFNA6ENSG00000120235Homo sapiens
 IFNA7ENSG00000214042Homo sapiens
 IFNA8ENSG00000120242Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ifna12 / Q80SS5 / Interferon alpha-12 / IFNA2* / IFNA1* / IFNA5* / IFNA4* / IFNA6* / IFNA7* / IFNA8* / P01571* / IFNA10* / IFNA13* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P0156...ENSMUSG0000007381190
Ifna5 / IFNA6* / IFNA7* / IFNA8* / IFNA1* / IFNA2* / IFNA4* / P32881* / IFNA10* / IFNA13* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P01563* / P01566* / P01567* / P01568* / P01569*...ENSMUSG0000009668290
Ifna7 / IFNA5* / IFNA6* / IFNA8* / IFNA1* / IFNA2* / IFNA4* / P32881* / IFNA10* / IFNA13* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P01563* / P01566* / P01567* / P01568* / P01569*...ENSMUSG0000010071389
Q80SU4 / Ifna13 / Interferon alpha-13 / IFNA7* / IFNA8* / IFNA1* / IFNA2* / IFNA4* / IFNA6* / IFNA5* / IFNA10* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P01563* / P01566* / P0156...ENSMUSG0000006337688
Ifna16 / IFNA6* / IFNA7* / IFNA4* / IFNA1* / IFNA2* / IFNA8* / IFNA5* / P32881* / IFNA10* / IFNA13* / IFNA14* / IFNA17* / IFNA21* / P01562* / P01563* / P01566* / P01567* / P01568* / P01569*...ENSMUSG0000007835588
Ifna14 / IFNA6* / IFNA7* / IFNA8* / IFNA2* / IFNA4* / IFNA1* / IFNA5* / P32881* / IFNA10* / IFNA13* / IFNA16* / IFNA17* / IFNA21* / P01562* / P01563* / P01566* / P01567* / P01568* / P01569*...ENSMUSG0000009589688
Ifna11 / Q61716 / Interferon alpha-11 / IFNA2* / IFNA1* / IFNA5* / IFNA4* / IFNA6* / IFNA7* / IFNA8* / P01571* / IFNA10* / IFNA13* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P0156...ENSMUSG0000010054988
Ifna6 / IFNA5* / IFNA7* / IFNA8* / IFNA1* / IFNA2* / IFNA4* / P32881* / IFNA10* / IFNA13* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P01563* / P01566* / P01567* / P01568* / P01569*...ENSMUSG0000010125288
Ifna15 / IFNA5* / IFNA6* / IFNA7* / IFNA8* / IFNA1* / IFNA2* / IFNA4* / P32881* / IFNA10* / IFNA13* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P01563* / P01566* / P01567* / P01568*...ENSMUSG0000009601187
Ifnab / IFNA6* / IFNA7* / IFNA8* / IFNA2* / IFNA4* / IFNA1* / IFNA5* / P32881* / IFNA10* / IFNA13* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P01563* / P01566* / P01567* / P01568* ...ENSMUSG0000010007987
Ifna2 / interferon alpha 2 / IFNA7* / IFNA8* / IFNA4* / IFNA1* / IFNA5* / IFNA6* / P32881* / IFNA10* / IFNA13* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P01563* / P01566* / P01567...ENSMUSG0000007835486
Ifna9 / P09235 / Interferon alpha-9 / IFNA1* / IFNA4* / IFNA6* / IFNA5* / IFNA7* / IFNA8* / IFNA2* / P32881* / IFNA10* / IFNA13* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P01563*...ENSMUSG0000009527085
Ifna4 / P07351 / Interferon alpha-4 / IFNA7* / IFNA5* / IFNA8* / IFNA2* / IFNA1* / IFNA6* / P32881* / IFNA10* / IFNA13* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P01563* / P01566...ENSMUSG0000007090478
Ifnk / Q7TSL0 / Interferon kappa / Q9P0W0*ENSMUSG0000004299327


Protein motifs (from Interpro)
Interpro ID Name
 IPR000471  Interferon alpha/beta/delta
 IPR009079  Four-helical cytokine-like, core


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IBA
 biological_processGO:0002286 T cell activation involved in immune response IDA
 biological_processGO:0002323 natural killer cell activation involved in immune response IDA
 biological_processGO:0006952 defense response IEA
 biological_processGO:0006959 humoral immune response IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030183 B cell differentiation IBA
 biological_processGO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein IBA
 biological_processGO:0042100 B cell proliferation IBA
 biological_processGO:0042742 defense response to bacterium IDA
 biological_processGO:0043330 response to exogenous dsRNA IBA
 biological_processGO:0050691 regulation of defense response to virus by host IDA
 biological_processGO:0051607 defense response to virus IDA
 biological_processGO:0060337 type I interferon signaling pathway IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005622 intracellular IDA
 molecular_functionGO:0005125 cytokine activity IDA
 molecular_functionGO:0005126 cytokine receptor binding IEA
 molecular_functionGO:0005132 type I interferon receptor binding IBA


Pathways (from Reactome)
Pathway description
Interferon alpha/beta signaling
Regulation of IFNA signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000022967 Ifnar1 / P33896 / Interferon alpha/beta receptor 1 / P17181* / interferon alpha and beta receptor subunit 1*  / complex
 ENSMUSG00000038037 Socs1 / O35716 / Suppressor of cytokine signaling 1 / O15524*  / complex / reaction






 

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