10013


Homo sapiens (NCBI)

Features
Gene ID: 10013
  
Biological name :
  
Synonyms : CPBHM|HD6|JM21|PPP1R90 / HDAC6 / histone deacetylase 6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 206846_s_at (Human Genome U133 Plus 2.0 Array)   211722_s_at (Human Genome U133 Plus 2.0 Array)   216224_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NP_001308155.1
RefSeq - NP_001308156.1
RefSeq - NP_001308157.1
RefSeq - NP_001308158.1
RefSeq - NP_001308159.1
RefSeq - NP_001308160.1
RefSeq - NP_006035.2
RefSeq - NC_000023.11
RefSeq - NG_012560.1
RefSeq - 1007392134
RefSeq - 1007392395
RefSeq - XP_016884676.1
RefSeq - 1007392590
RefSeq - 1007392609
RefSeq - 1007392633
RefSeq - 1007392892
RefSeq - 1007391942
RefSeq - 1034673261
RefSeq - 13128864
RefSeq - NP_001308154.1
RefSeq - XR_246712.2
RefSeq - NM_001321225.1
RefSeq - NM_001321226.1
RefSeq - NM_001321227.1
RefSeq - NM_001321228.1
RefSeq - NM_001321229.1
RefSeq - NM_001321230.1
RefSeq - NM_001321231.1
RefSeq - NM_006044.3
RefSeq - NR_135591.1
RefSeq - NR_135592.1
RefSeq - NR_135593.1
RefSeq - XM_017029187.1
RefSeq - XR_001755632.2
RefSeq - XR_002958755.1
RefSeq - XR_002958756.1
RefSeq - XR_002958757.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000094631 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006476 protein deacetylation TAS
 biological_processGO:0006515 protein quality control for misfolded or incompletely synthesized proteins IMP
 biological_processGO:0006886 intracellular protein transport IMP
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0007026 negative regulation of microtubule depolymerization IEA
 biological_processGO:0009636 response to toxic substance IMP
 biological_processGO:0009967 positive regulation of signal transduction IMP
 biological_processGO:0010033 response to organic substance IMP
 biological_processGO:0010469 regulation of signaling receptor activity IMP
 biological_processGO:0010506 regulation of autophagy TAS
 biological_processGO:0010634 positive regulation of epithelial cell migration IMP
 biological_processGO:0010727 negative regulation of hydrogen peroxide metabolic process IC
 biological_processGO:0010870 positive regulation of receptor biosynthetic process IMP
 biological_processGO:0016241 regulation of macroautophagy IMP
 biological_processGO:0016575 histone deacetylation ISS
 biological_processGO:0031647 regulation of protein stability IMP
 biological_processGO:0032418 lysosome localization IMP
 biological_processGO:0032461 positive regulation of protein oligomerization IMP
 biological_processGO:0032984 protein-containing complex disassembly IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IMP
 biological_processGO:0034983 peptidyl-lysine deacetylation IMP
 biological_processGO:0035967 cellular response to topologically incorrect protein IMP
 biological_processGO:0040029 regulation of gene expression, epigenetic IMP
 biological_processGO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IEA
 biological_processGO:0043242 negative regulation of protein complex disassembly IMP
 biological_processGO:0045598 regulation of fat cell differentiation IEA
 biological_processGO:0045861 negative regulation of proteolysis IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISS
 biological_processGO:0048668 collateral sprouting IEA
 biological_processGO:0051354 negative regulation of oxidoreductase activity IC
 biological_processGO:0051646 mitochondrion localization IEA
 biological_processGO:0051788 response to misfolded protein IMP
 biological_processGO:0060271 cilium assembly TAS
 biological_processGO:0060632 regulation of microtubule-based movement IC
 biological_processGO:0060765 regulation of androgen receptor signaling pathway TAS
 biological_processGO:0060997 dendritic spine morphogenesis IEA
 biological_processGO:0061734 parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization IGI
 biological_processGO:0070201 regulation of establishment of protein localization IEA
 biological_processGO:0070301 cellular response to hydrogen peroxide IMP
 biological_processGO:0070842 aggresome assembly IMP
 biological_processGO:0070845 polyubiquitinated misfolded protein transport IMP
 biological_processGO:0070846 Hsp90 deacetylation IMP
 biological_processGO:0070848 response to growth factor IMP
 biological_processGO:0070932 histone H3 deacetylation IEA
 biological_processGO:0071218 cellular response to misfolded protein IEA
 biological_processGO:0090035 positive regulation of chaperone-mediated protein complex assembly IMP
 biological_processGO:0090042 tubulin deacetylation TAS
 biological_processGO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death IDA
 biological_processGO:1903146 regulation of autophagy of mitochondrion TAS
 cellular_componentGO:0000118 histone deacetylase complex IDA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005771 multivesicular body TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005874 microtubule IDA
 cellular_componentGO:0005875 microtubule associated complex IDA
 cellular_componentGO:0005881 cytoplasmic microtubule IEA
 cellular_componentGO:0005901 caveola IDA
 cellular_componentGO:0016234 inclusion body IDA
 cellular_componentGO:0016235 aggresome TAS
 cellular_componentGO:0030286 dynein complex IDA
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0031252 cell leading edge IDA
 cellular_componentGO:0043204 perikaryon ISS
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0004407 histone deacetylase activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008013 beta-catenin binding IPI
 molecular_functionGO:0008017 microtubule binding ISS
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0019899 enzyme binding ISS
 molecular_functionGO:0031593 polyubiquitin modification-dependent protein binding IDA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific) IEA
 molecular_functionGO:0042826 histone deacetylase binding IPI
 molecular_functionGO:0042903 tubulin deacetylase activity TAS
 molecular_functionGO:0043014 alpha-tubulin binding IDA
 molecular_functionGO:0043130 ubiquitin binding IEA
 molecular_functionGO:0048156 tau protein binding TAS
 molecular_functionGO:0048487 beta-tubulin binding IEA
 molecular_functionGO:0051787 misfolded protein binding EXP
 molecular_functionGO:0051879 Hsp90 protein binding IDA
 molecular_functionGO:0070840 dynein complex binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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