11350


Mus musculus (NCBI)

Features
Gene ID: 11350
  
Biological name :
  
Synonyms : Abl1 / AI325092|Abl|E430008G22Rik|c-Abl / c-abl oncogene 1, non-receptor tyrosine kinase
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1423999_at (Mouse Genome 430 2.0 Array)   1441291_at (Mouse Genome 430 2.0 Array)   1444134_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 162951865
RefSeq - 162951870
RefSeq - 545687252
RefSeq - 545687676
RefSeq - 545687805
RefSeq - 568912812
RefSeq - NC_000068.7
RefSeq - NP_001106174.1
RefSeq - NP_001269974.1
RefSeq - NP_001269975.1
RefSeq - NP_001269976.1
RefSeq - NP_033724.2
RefSeq - XP_006497684.1
RefSeq - NM_001112703.2
RefSeq - NM_001283045.1
RefSeq - NM_001283046.1
RefSeq - NM_001283047.1
RefSeq - NM_009594.4
RefSeq - XM_006497621.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000026842 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001843 neural tube closure IGI
 biological_processGO:0001922 B-1 B cell homeostasis IMP
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0002322 B cell proliferation involved in immune response IMP
 biological_processGO:0002333 transitional one stage B cell differentiation IMP
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006468 protein phosphorylation ISO
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0006909 phagocytosis IMP
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus ISO
 biological_processGO:0006975 DNA damage induced protein phosphorylation ISO
 biological_processGO:0006979 response to oxidative stress ISO
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IBA
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway IGI
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration ISO
 biological_processGO:0007229 integrin-mediated signaling pathway ISO
 biological_processGO:0009791 post-embryonic development IGI
 biological_processGO:0010595 positive regulation of endothelial cell migration ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0021587 cerebellum morphogenesis IGI
 biological_processGO:0022408 negative regulation of cell-cell adhesion IGI
 biological_processGO:0030035 microspike assembly IDA
 biological_processGO:0030036 actin cytoskeleton organization IGI
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030182 neuron differentiation IGI
 biological_processGO:0030514 negative regulation of BMP signaling pathway IMP
 biological_processGO:0030516 regulation of axon extension ISO
 biological_processGO:0031113 regulation of microtubule polymerization ISO
 biological_processGO:0032489 regulation of Cdc42 protein signal transduction ISO
 biological_processGO:0032956 regulation of actin cytoskeleton organization ISO
 biological_processGO:0033690 positive regulation of osteoblast proliferation IMP
 biological_processGO:0034446 substrate adhesion-dependent cell spreading IDA
 biological_processGO:0035791 platelet-derived growth factor receptor-beta signaling pathway ISO
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation ISO
 biological_processGO:0038189 neuropilin signaling pathway ISO
 biological_processGO:0042100 B cell proliferation IMP
 biological_processGO:0042127 regulation of cell proliferation IGI
 biological_processGO:0042770 signal transduction in response to DNA damage ISO
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043065 positive regulation of apoptotic process ISO
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IGI
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling IMP
 biological_processGO:0043542 endothelial cell migration ISO
 biological_processGO:0045087 innate immune response IBA
 biological_processGO:0045184 establishment of protein localization ISO
 biological_processGO:0045580 regulation of T cell differentiation IMP
 biological_processGO:0045930 negative regulation of mitotic cell cycle IGI
 biological_processGO:0045931 positive regulation of mitotic cell cycle IGI
 biological_processGO:0046632 alpha-beta T cell differentiation IGI
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0048008 platelet-derived growth factor receptor signaling pathway IMP
 biological_processGO:0048536 spleen development IMP
 biological_processGO:0048538 thymus development IMP
 biological_processGO:0048668 collateral sprouting IMP
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0050798 activated T cell proliferation IMP
 biological_processGO:0050853 B cell receptor signaling pathway IMP
 biological_processGO:0050885 neuromuscular process controlling balance IGI
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol IGI
 biological_processGO:0051353 positive regulation of oxidoreductase activity ISO
 biological_processGO:0051444 negative regulation of ubiquitin-protein transferase activity ISO
 biological_processGO:0051496 positive regulation of stress fiber assembly ISO
 biological_processGO:0051726 regulation of cell cycle IDA
 biological_processGO:0051894 positive regulation of focal adhesion assembly ISO
 biological_processGO:0060020 Bergmann glial cell differentiation IGI
 biological_processGO:0060563 neuroepithelial cell differentiation IGI
 biological_processGO:0070301 cellular response to hydrogen peroxide ISO
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0071222 cellular response to lipopolysaccharide IMP
 biological_processGO:0071901 negative regulation of protein serine/threonine kinase activity ISO
 biological_processGO:0072358 cardiovascular system development IGI
 biological_processGO:0090050 positive regulation of cell migration involved in sprouting angiogenesis IDA
 biological_processGO:0090135 actin filament branching IMP
 biological_processGO:1900026 positive regulation of substrate adhesion-dependent cell spreading ISO
 biological_processGO:1900042 positive regulation of interleukin-2 secretion IGI
 biological_processGO:1900272 negative regulation of long-term synaptic potentiation IGI
 biological_processGO:1900275 negative regulation of phospholipase C activity ISO
 biological_processGO:1901216 positive regulation of neuron death IMP
 biological_processGO:1902715 positive regulation of interferon-gamma secretion IGI
 biological_processGO:1903053 regulation of extracellular matrix organization IGI
 biological_processGO:1904528 positive regulation of microtubule binding ISO
 biological_processGO:1904531 positive regulation of actin filament binding ISO
 biological_processGO:1905244 regulation of modification of synaptic structure IGI
 biological_processGO:1905555 positive regulation blood vessel branching IMP
 biological_processGO:1990051 activation of protein kinase C activity ISO
 biological_processGO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway IGI
 biological_processGO:2000251 positive regulation of actin cytoskeleton reorganization ISO
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process IGI
 biological_processGO:2000772 regulation of cellular senescence IGI
 biological_processGO:2000773 negative regulation of cellular senescence IGI
 biological_processGO:2001020 regulation of response to DNA damage stimulus ISO
 cellular_componentGO:0001726 ruffle ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0016604 nuclear body ISO
 cellular_componentGO:0030425 dendrite ISO
 cellular_componentGO:0030426 growth cone ISO
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IBA
 cellular_componentGO:0031252 cell leading edge IDA
 cellular_componentGO:0032991 protein-containing complex ISO
 cellular_componentGO:0043005 neuron projection ISO
 cellular_componentGO:0043025 neuronal cell body ISO
 cellular_componentGO:0045202 synapse ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding ISO
 molecular_functionGO:0001784 phosphotyrosine residue binding ISO
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004672 protein kinase activity ISO
 molecular_functionGO:0004713 protein tyrosine kinase activity ISO
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity ISO
 molecular_functionGO:0005080 protein kinase C binding ISO
 molecular_functionGO:0005102 signaling receptor binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding ISO
 molecular_functionGO:0008022 protein C-terminus binding ISO
 molecular_functionGO:0016301 kinase activity ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017124 SH3 domain binding ISO
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0019905 syntaxin binding ISO
 molecular_functionGO:0030145 manganese ion binding ISO
 molecular_functionGO:0038191 neuropilin binding ISO
 molecular_functionGO:0042169 SH2 domain binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046875 ephrin receptor binding IPI
 molecular_functionGO:0051015 actin filament binding IDA
 molecular_functionGO:0051019 mitogen-activated protein kinase binding ISO
 molecular_functionGO:0070064 proline-rich region binding ISO
 molecular_functionGO:0070097 delta-catenin binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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