142


Homo sapiens (NCBI)

Features
Gene ID: 142
  
Biological name :
  
Synonyms : ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1 / PARP1 / poly(ADP-ribose) polymerase 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 208644_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 156523968
RefSeq - NC_000001.11
RefSeq - NP_001609.2
RefSeq - NM_001618.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000143799 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II TAS
 biological_processGO:0000715 nucleotide-excision repair, DNA damage recognition TAS
 biological_processGO:0000723 telomere maintenance TAS
 biological_processGO:0000724 double-strand break repair via homologous recombination TAS
 biological_processGO:0006281 DNA repair TAS
 biological_processGO:0006293 nucleotide-excision repair, preincision complex stabilization TAS
 biological_processGO:0006294 nucleotide-excision repair, preincision complex assembly TAS
 biological_processGO:0006296 nucleotide-excision repair, DNA incision, 5"-to lesion TAS
 biological_processGO:0006302 double-strand break repair IMP
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006471 protein ADP-ribosylation IMP
 biological_processGO:0006915 apoptotic process IDA
 biological_processGO:0006974 cellular response to DNA damage stimulus IMP
 biological_processGO:0007005 mitochondrion organization IMP
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0010332 response to gamma radiation IEA
 biological_processGO:0010613 positive regulation of cardiac muscle hypertrophy ISS
 biological_processGO:0010990 regulation of SMAD protein complex assembly IEA
 biological_processGO:0016540 protein autoprocessing IEA
 biological_processGO:0018312 peptidyl-serine ADP-ribosylation IDA
 biological_processGO:0023019 signal transduction involved in regulation of gene expression IEA
 biological_processGO:0030225 macrophage differentiation TAS
 biological_processGO:0032042 mitochondrial DNA metabolic process IMP
 biological_processGO:0032869 cellular response to insulin stimulus IDA
 biological_processGO:0033148 positive regulation of intracellular estrogen receptor signaling pathway IEA
 biological_processGO:0033683 nucleotide-excision repair, DNA incision TAS
 biological_processGO:0034599 cellular response to oxidative stress IMP
 biological_processGO:0034644 cellular response to UV IMP
 biological_processGO:0036211 protein modification process IMP
 biological_processGO:0042769 DNA damage response, detection of DNA damage IEA
 biological_processGO:0043504 mitochondrial DNA repair IMP
 biological_processGO:0044030 regulation of DNA methylation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0050790 regulation of catalytic activity IDA
 biological_processGO:0051901 positive regulation of mitochondrial depolarization IEA
 biological_processGO:0060391 positive regulation of SMAD protein signal transduction IEA
 biological_processGO:0070212 protein poly-ADP-ribosylation IDA
 biological_processGO:0070911 global genome nucleotide-excision repair TAS
 biological_processGO:0071294 cellular response to zinc ion IEA
 biological_processGO:1900182 positive regulation of protein localization to nucleus IEA
 biological_processGO:1901216 positive regulation of neuron death IEA
 biological_processGO:1903376 regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway IEA
 biological_processGO:1903518 positive regulation of single strand break repair IGI
 biological_processGO:1903827 regulation of cellular protein localization IMP
 biological_processGO:1904044 response to aldosterone IEA
 biological_processGO:1904357 negative regulation of telomere maintenance via telomere lengthening ISS
 biological_processGO:1904646 cellular response to amyloid-beta IEA
 biological_processGO:1904762 positive regulation of myofibroblast differentiation IEA
 biological_processGO:1990966 ATP generation from poly-ADP-D-ribose IDA
 biological_processGO:2000679 positive regulation of transcription regulatory region DNA binding IEA
 biological_processGO:2001170 negative regulation of ATP biosynthetic process IMP
 cellular_componentGO:0000784 nuclear chromosome, telomeric region HDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005635 nuclear envelope IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005667 transcription factor complex IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0032993 protein-DNA complex IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003950 NAD+ ADP-ribosyltransferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0030331 estrogen receptor binding IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042826 histone deacetylase binding IEA
 molecular_functionGO:0047485 protein N-terminus binding IPI
 molecular_functionGO:0051287 NAD binding IEA
 molecular_functionGO:0070412 R-SMAD binding IEA
 molecular_functionGO:1990404 protein ADP-ribosylase activity IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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