17535


Mus musculus (NCBI)

Features
Gene ID: 17535
  
Biological name :
  
Synonyms : Mre11a / MRE11A homolog A, double strand break repair nuclease / Mre11|Mre11b
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1416748_a_at (Mouse Genome 430 2.0 Array)   1441990_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 9055282
RefSeq - NC_000075.6
RefSeq - XP_006510111.1
RefSeq - XP_006510112.1
RefSeq - XP_006510114.1
RefSeq - XP_006510115.1
RefSeq - XP_006510116.1
RefSeq - XP_006510117.1
RefSeq - 568958923
RefSeq - 568958925
RefSeq - 568958929
RefSeq - NP_001297657.1
RefSeq - NP_061206.1
RefSeq - 568958931
RefSeq - 568958933
RefSeq - 568958936
RefSeq - 895799647
RefSeq - XR_379107.2
RefSeq - NM_001310728.1
RefSeq - NM_018736.3
RefSeq - XM_006510048.2
RefSeq - XM_006510049.2
RefSeq - XM_006510051.2
RefSeq - XM_006510052.2
RefSeq - XM_006510053.1
RefSeq - XM_006510054.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000031928 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000723 telomere maintenance IBA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006284 base-excision repair IBA
 biological_processGO:0006302 double-strand break repair IMP
 biological_processGO:0006303 double-strand break repair via nonhomologous end joining ISO
 biological_processGO:0006974 cellular response to DNA damage stimulus ISO
 biological_processGO:0007062 sister chromatid cohesion ISO
 biological_processGO:0007095 mitotic G2 DNA damage checkpoint IMP
 biological_processGO:0007129 synapsis IMP
 biological_processGO:0008283 cell proliferation IMP
 biological_processGO:0031573 intra-S DNA damage checkpoint IMP
 biological_processGO:0031860 telomeric 3" overhang formation ISO
 biological_processGO:0031954 positive regulation of protein autophosphorylation ISO
 biological_processGO:0032206 positive regulation of telomere maintenance ISO
 biological_processGO:0032508 DNA duplex unwinding ISO
 biological_processGO:0032876 negative regulation of DNA endoreduplication ISO
 biological_processGO:0033674 positive regulation of kinase activity ISO
 biological_processGO:0042138 meiotic DNA double-strand break formation IBA
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0046597 negative regulation of viral entry into host cell ISO
 biological_processGO:0051276 chromosome organization IMP
 biological_processGO:0051321 meiotic cell cycle IEA
 biological_processGO:0097552 mitochondrial double-strand break repair via homologous recombination IBA
 cellular_componentGO:0000781 chromosome, telomeric region ISO
 cellular_componentGO:0000784 nuclear chromosome, telomeric region ISO
 cellular_componentGO:0000785 chromatin IBA
 cellular_componentGO:0000790 nuclear chromatin ISO
 cellular_componentGO:0000794 condensed nuclear chromosome ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0016605 PML body ISO
 cellular_componentGO:0030870 Mre11 complex ISO
 cellular_componentGO:0035861 site of double-strand break ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 molecular_functionGO:0000014 single-stranded DNA endodeoxyribonuclease activity ISO
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003691 double-stranded telomeric DNA binding IBA
 molecular_functionGO:0004003 ATP-dependent DNA helicase activity ISO
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0004520 endodeoxyribonuclease activity ISO
 molecular_functionGO:0004527 exonuclease activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008022 protein C-terminus binding ISO
 molecular_functionGO:0008408 3"-5" exonuclease activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030145 manganese ion binding IEA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0043047 single-stranded telomeric DNA binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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