20423


Mus musculus (NCBI)

Features
Gene ID: 20423
  
Biological name :
  
Synonyms : 9530036O11Rik|Dsh|Hhg1|Hx|Hxl3|M100081|ShhNC / Shh / sonic hedgehog
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1427571_at (Mouse Genome 430 2.0 Array)   1436869_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - XP_006535712.1
RefSeq - 568933057
RefSeq - 568933059
RefSeq - NC_000071.6
RefSeq - NP_033196.1
RefSeq - XP_006535711.1
RefSeq - 21617861
RefSeq - NM_009170.3
RefSeq - XM_006535649.3
RefSeq - XM_006535648.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000002633 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0001569 branching involved in blood vessel morphogenesis IMP
 biological_processGO:0001570 vasculogenesis IDA
 biological_processGO:0001656 metanephros development IMP
 biological_processGO:0001658 branching involved in ureteric bud morphogenesis IMP
 biological_processGO:0001708 cell fate specification IMP
 biological_processGO:0001755 neural crest cell migration IMP
 biological_processGO:0001822 kidney development IMP
 biological_processGO:0001841 neural tube formation ISO
 biological_processGO:0001942 hair follicle development IMP
 biological_processGO:0001944 vasculature development IMP
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0002052 positive regulation of neuroblast proliferation ISO
 biological_processGO:0002053 positive regulation of mesenchymal cell proliferation IMP
 biological_processGO:0002076 osteoblast development IDA
 biological_processGO:0002320 lymphoid progenitor cell differentiation ISO
 biological_processGO:0003140 determination of left/right asymmetry in lateral mesoderm IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IMP
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006897 endocytosis IDA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007224 smoothened signaling pathway IMP
 biological_processGO:0007228 positive regulation of hh target transcription factor activity IMP
 biological_processGO:0007267 cell-cell signaling IMP
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007368 determination of left/right symmetry IMP
 biological_processGO:0007389 pattern specification process IMP
 biological_processGO:0007398 ectoderm development IMP
 biological_processGO:0007405 neuroblast proliferation IDA
 biological_processGO:0007411 axon guidance IMP
 biological_processGO:0007417 central nervous system development IMP
 biological_processGO:0007442 hindgut morphogenesis IMP
 biological_processGO:0007502 digestive tract mesoderm development ISO
 biological_processGO:0007507 heart development IMP
 biological_processGO:0007596 blood coagulation IMP
 biological_processGO:0008209 androgen metabolic process IMP
 biological_processGO:0008283 cell proliferation IGI
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0009949 polarity specification of anterior/posterior axis IMP
 biological_processGO:0009952 anterior/posterior pattern specification IMP
 biological_processGO:0009953 dorsal/ventral pattern formation IGI
 biological_processGO:0010463 mesenchymal cell proliferation IMP
 biological_processGO:0010468 regulation of gene expression ISO
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0010629 negative regulation of gene expression IMP
 biological_processGO:0014003 oligodendrocyte development IDA
 biological_processGO:0014706 striated muscle tissue development IMP
 biological_processGO:0014858 positive regulation of skeletal muscle cell proliferation IMP
 biological_processGO:0014902 myotube differentiation IMP
 biological_processGO:0016539 intein-mediated protein splicing IEA
 biological_processGO:0021513 spinal cord dorsal/ventral patterning ISO
 biological_processGO:0021521 ventral spinal cord interneuron specification ISO
 biological_processGO:0021522 spinal cord motor neuron differentiation IGI
 biological_processGO:0021794 thalamus development IMP
 biological_processGO:0021871 forebrain regionalization IMP
 biological_processGO:0021904 dorsal/ventral neural tube patterning IMP
 biological_processGO:0021924 cell proliferation in external granule layer IDA
 biological_processGO:0021930 cerebellar granule cell precursor proliferation IGI
 biological_processGO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation IMP
 biological_processGO:0021940 positive regulation of cerebellar granule cell precursor proliferation IDA
 biological_processGO:0021978 telencephalon regionalization ISO
 biological_processGO:0022006 zona limitans intrathalamica formation ISO
 biological_processGO:0030010 establishment of cell polarity IDA
 biological_processGO:0030162 regulation of proteolysis IDA
 biological_processGO:0030177 positive regulation of Wnt signaling pathway IMP
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IDA
 biological_processGO:0030323 respiratory tube development IMP
 biological_processGO:0030324 lung development IMP
 biological_processGO:0030326 embryonic limb morphogenesis IMP
 biological_processGO:0030336 negative regulation of cell migration IDA
 biological_processGO:0030539 male genitalia development IMP
 biological_processGO:0030850 prostate gland development IMP
 biological_processGO:0030878 thyroid gland development IMP
 biological_processGO:0030900 forebrain development IGI
 biological_processGO:0030901 midbrain development IGI
 biological_processGO:0030902 hindbrain development IMP
 biological_processGO:0031016 pancreas development IMP
 biological_processGO:0031069 hair follicle morphogenesis IMP
 biological_processGO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process IMP
 biological_processGO:0032901 positive regulation of neurotrophin production ISO
 biological_processGO:0033077 T cell differentiation in thymus IMP
 biological_processGO:0033089 positive regulation of T cell differentiation in thymus IMP
 biological_processGO:0033092 positive regulation of immature T cell proliferation in thymus IMP
 biological_processGO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter IDA
 biological_processGO:0034504 protein localization to nucleus IDA
 biological_processGO:0035115 embryonic forelimb morphogenesis IMP
 biological_processGO:0035116 embryonic hindlimb morphogenesis IMP
 biological_processGO:0042127 regulation of cell proliferation ISO
 biological_processGO:0042130 negative regulation of T cell proliferation IMP
 biological_processGO:0042177 negative regulation of protein catabolic process IMP
 biological_processGO:0042307 positive regulation of protein import into nucleus IGI
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IMP
 biological_processGO:0042476 odontogenesis IDA
 biological_processGO:0042481 regulation of odontogenesis IMP
 biological_processGO:0042733 embryonic digit morphogenesis IMP
 biological_processGO:0043010 camera-type eye development IMP
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043369 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment ISO
 biological_processGO:0043586 tongue development ISO
 biological_processGO:0043587 tongue morphogenesis ISO
 biological_processGO:0043588 skin development IMP
 biological_processGO:0045059 positive thymic T cell selection IMP
 biological_processGO:0045060 negative thymic T cell selection IMP
 biological_processGO:0045109 intermediate filament organization IMP
 biological_processGO:0045165 cell fate commitment IGI
 biological_processGO:0045445 myoblast differentiation IDA
 biological_processGO:0045471 response to ethanol ISO
 biological_processGO:0045596 negative regulation of cell differentiation IMP
 biological_processGO:0045597 positive regulation of cell differentiation IMP
 biological_processGO:0045666 positive regulation of neuron differentiation ISO
 biological_processGO:0045880 positive regulation of smoothened signaling pathway ISO
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0046534 positive regulation of photoreceptor cell differentiation ISO
 biological_processGO:0046638 positive regulation of alpha-beta T cell differentiation IMP
 biological_processGO:0046639 negative regulation of alpha-beta T cell differentiation IMP
 biological_processGO:0048468 cell development IMP
 biological_processGO:0048538 thymus development IMP
 biological_processGO:0048546 digestive tract morphogenesis IMP
 biological_processGO:0048557 embryonic digestive tract morphogenesis TAS
 biological_processGO:0048568 embryonic organ development IMP
 biological_processGO:0048589 developmental growth IMP
 biological_processGO:0048598 embryonic morphogenesis IMP
 biological_processGO:0048617 embryonic foregut morphogenesis IMP
 biological_processGO:0048643 positive regulation of skeletal muscle tissue development IMP
 biological_processGO:0048645 animal organ formation IMP
 biological_processGO:0048646 anatomical structure formation involved in morphogenesis IMP
 biological_processGO:0048663 neuron fate commitment IMP
 biological_processGO:0048678 response to axon injury ISO
 biological_processGO:0048706 embryonic skeletal system development IGI
 biological_processGO:0048709 oligodendrocyte differentiation IGI
 biological_processGO:0048714 positive regulation of oligodendrocyte differentiation IDA
 biological_processGO:0048754 branching morphogenesis of an epithelial tube IMP
 biological_processGO:0048808 male genitalia morphogenesis ISO
 biological_processGO:0048839 inner ear development IMP
 biological_processGO:0048856 anatomical structure development IMP
 biological_processGO:0048859 formation of anatomical boundary IMP
 biological_processGO:0048864 stem cell development IMP
 biological_processGO:0051146 striated muscle cell differentiation IMP
 biological_processGO:0051155 positive regulation of striated muscle cell differentiation IMP
 biological_processGO:0051781 positive regulation of cell division ISO
 biological_processGO:0060020 Bergmann glial cell differentiation IDA
 biological_processGO:0060021 roof of mouth development IMP
 biological_processGO:0060070 canonical Wnt signaling pathway IDA
 biological_processGO:0060173 limb development IMP
 biological_processGO:0060174 limb bud formation IMP
 biological_processGO:0060406 positive regulation of penile erection ISO
 biological_processGO:0060425 lung morphogenesis IMP
 biological_processGO:0060428 lung epithelium development IMP
 biological_processGO:0060438 trachea development IMP
 biological_processGO:0060439 trachea morphogenesis IMP
 biological_processGO:0060441 epithelial tube branching involved in lung morphogenesis IMP
 biological_processGO:0060442 branching involved in prostate gland morphogenesis IDA
 biological_processGO:0060445 branching involved in salivary gland morphogenesis IMP
 biological_processGO:0060447 bud outgrowth involved in lung branching IMP
 biological_processGO:0060458 right lung development IMP
 biological_processGO:0060459 left lung development IMP
 biological_processGO:0060463 lung lobe morphogenesis IMP
 biological_processGO:0060484 lung-associated mesenchyme development IMP
 biological_processGO:0060513 prostatic bud formation IGI
 biological_processGO:0060516 primary prostatic bud elongation IDA
 biological_processGO:0060523 prostate epithelial cord elongation IDA
 biological_processGO:0060662 salivary gland cavitation IDA
 biological_processGO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis IMP
 biological_processGO:0060684 epithelial-mesenchymal cell signaling IMP
 biological_processGO:0060685 regulation of prostatic bud formation IMP
 biological_processGO:0060738 epithelial-mesenchymal signaling involved in prostate gland development ISO
 biological_processGO:0060768 regulation of epithelial cell proliferation involved in prostate gland development IMP
 biological_processGO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development IMP
 biological_processGO:0060782 regulation of mesenchymal cell proliferation involved in prostate gland development IMP
 biological_processGO:0060783 mesenchymal smoothened signaling pathway involved in prostate gland development IMP
 biological_processGO:0060840 artery development IMP
 biological_processGO:0060916 mesenchymal cell proliferation involved in lung development IDA
 biological_processGO:0060979 vasculogenesis involved in coronary vascular morphogenesis TAS
 biological_processGO:0061053 somite development IMP
 biological_processGO:0061189 positive regulation of sclerotome development ISO
 biological_processGO:0061196 fungiform papilla development ISO
 biological_processGO:0061197 fungiform papilla morphogenesis ISO
 biological_processGO:0061198 fungiform papilla formation ISO
 biological_processGO:0070447 positive regulation of oligodendrocyte progenitor proliferation ISO
 biological_processGO:0071285 cellular response to lithium ion IDA
 biological_processGO:0071542 dopaminergic neuron differentiation TAS
 biological_processGO:0071679 commissural neuron axon guidance ISO
 biological_processGO:0072136 metanephric mesenchymal cell proliferation involved in metanephros development IMP
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IMP
 biological_processGO:0090370 negative regulation of cholesterol efflux IMP
 biological_processGO:0097190 apoptotic signaling pathway IDA
 biological_processGO:1900180 regulation of protein localization to nucleus ISO
 biological_processGO:1901215 negative regulation of neuron death ISO
 biological_processGO:1903672 positive regulation of sprouting angiogenesis ISO
 biological_processGO:1904339 negative regulation of dopaminergic neuron differentiation IMP
 biological_processGO:1905327 tracheoesophageal septum formation IMP
 biological_processGO:2000062 negative regulation of ureter smooth muscle cell differentiation IDA
 biological_processGO:2000063 positive regulation of ureter smooth muscle cell differentiation IMP
 biological_processGO:2000357 negative regulation of kidney smooth muscle cell differentiation IDA
 biological_processGO:2000358 positive regulation of kidney smooth muscle cell differentiation IDA
 biological_processGO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development IMP
 biological_processGO:2001028 positive regulation of endothelial cell chemotaxis ISO
 biological_processGO:2001054 negative regulation of mesenchymal cell apoptotic process IMP
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0008021 synaptic vesicle ISO
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0030133 transport vesicle ISO
 cellular_componentGO:0030424 axon ISO
 cellular_componentGO:0030425 dendrite ISO
 cellular_componentGO:0031012 extracellular matrix IDA
 cellular_componentGO:0043025 neuronal cell body ISO
 cellular_componentGO:0045121 membrane raft ISO
 molecular_functionGO:0005113 patched binding ISO
 molecular_functionGO:0005509 calcium ion binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005539 glycosaminoglycan binding IDA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding ISO
 molecular_functionGO:0016787 hydrolase activity IDA
 molecular_functionGO:0043237 laminin-1 binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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