21808


Mus musculus (NCBI)

Features
Gene ID: 21808
  
Biological name :
  
Synonyms : BB105277|Tgf-beta2|Tgfb-2 / Tgfb2 / transforming growth factor, beta 2
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1423250_a_at (Mouse Genome 430 2.0 Array)   1438303_at (Mouse Genome 430 2.0 Array)   1450922_a_at (Mouse Genome 430 2.0 Array)   1450923_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 1041817895
RefSeq - 166706905
RefSeq - 568911644
RefSeq - 568911646
RefSeq - NC_000067.6
RefSeq - NP_001316036.1
RefSeq - NP_033393.2
RefSeq - XP_006497198.1
RefSeq - XP_006497199.1
RefSeq - NM_001329107.1
RefSeq - NM_009367.4
RefSeq - XM_006497135.3
RefSeq - XM_006497136.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000039239 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000902 cell morphogenesis ISO
 biological_processGO:0001501 skeletal system development IMP
 biological_processGO:0001502 cartilage condensation IGI
 biological_processGO:0001568 blood vessel development IMP
 biological_processGO:0001654 eye development ISO
 biological_processGO:0001666 response to hypoxia ISO
 biological_processGO:0001822 kidney development IMP
 biological_processGO:0001837 epithelial to mesenchymal transition ISO
 biological_processGO:0001843 neural tube closure IMP
 biological_processGO:0001942 hair follicle development ISO
 biological_processGO:0001974 blood vessel remodeling IMP
 biological_processGO:0003007 heart morphogenesis ISO
 biological_processGO:0003148 outflow tract septum morphogenesis IMP
 biological_processGO:0003149 membranous septum morphogenesis IMP
 biological_processGO:0003151 outflow tract morphogenesis TAS
 biological_processGO:0003179 heart valve morphogenesis IMP
 biological_processGO:0003181 atrioventricular valve morphogenesis IMP
 biological_processGO:0003184 pulmonary valve morphogenesis IMP
 biological_processGO:0003203 endocardial cushion morphogenesis IMP
 biological_processGO:0003214 cardiac left ventricle morphogenesis TAS
 biological_processGO:0003215 cardiac right ventricle morphogenesis TAS
 biological_processGO:0003222 ventricular trabecula myocardium morphogenesis IMP
 biological_processGO:0003274 endocardial cushion fusion IMP
 biological_processGO:0003289 atrial septum primum morphogenesis IMP
 biological_processGO:0003407 neural retina development IMP
 biological_processGO:0006468 protein phosphorylation ISO
 biological_processGO:0007050 cell cycle arrest ISO
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway ISO
 biological_processGO:0007411 axon guidance IMP
 biological_processGO:0007507 heart development ISO
 biological_processGO:0008219 cell death ISO
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0008285 negative regulation of cell proliferation ISO
 biological_processGO:0008347 glial cell migration ISO
 biological_processGO:0008584 male gonad development IMP
 biological_processGO:0010002 cardioblast differentiation ISO
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0010629 negative regulation of gene expression ISO
 biological_processGO:0010634 positive regulation of epithelial cell migration ISO
 biological_processGO:0010693 negative regulation of alkaline phosphatase activity ISO
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition ISO
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IBA
 biological_processGO:0010936 negative regulation of macrophage cytokine production ISO
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling ISO
 biological_processGO:0016477 cell migration ISO
 biological_processGO:0016525 negative regulation of angiogenesis ISO
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0030198 extracellular matrix organization IMP
 biological_processGO:0030199 collagen fibril organization ISO
 biological_processGO:0030307 positive regulation of cell growth ISO
 biological_processGO:0030308 negative regulation of cell growth ISO
 biological_processGO:0030326 embryonic limb morphogenesis IMP
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0031069 hair follicle morphogenesis IMP
 biological_processGO:0032147 activation of protein kinase activity ISO
 biological_processGO:0032570 response to progesterone ISO
 biological_processGO:0032874 positive regulation of stress-activated MAPK cascade ISO
 biological_processGO:0032909 regulation of transforming growth factor beta2 production ISO
 biological_processGO:0032956 regulation of actin cytoskeleton organization IDA
 biological_processGO:0033630 positive regulation of cell adhesion mediated by integrin ISO
 biological_processGO:0035910 ascending aorta morphogenesis IMP
 biological_processGO:0042060 wound healing ISO
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0042416 dopamine biosynthetic process IMP
 biological_processGO:0042493 response to drug ISO
 biological_processGO:0042981 regulation of apoptotic process IMP
 biological_processGO:0043065 positive regulation of apoptotic process ISO
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043408 regulation of MAPK cascade IBA
 biological_processGO:0043525 positive regulation of neuron apoptotic process ISO
 biological_processGO:0043627 response to estrogen ISO
 biological_processGO:0045216 cell-cell junction organization ISO
 biological_processGO:0045617 negative regulation of keratinocyte differentiation NAS
 biological_processGO:0045726 positive regulation of integrin biosynthetic process ISO
 biological_processGO:0045747 positive regulation of Notch signaling pathway ISO
 biological_processGO:0045787 positive regulation of cell cycle IMP
 biological_processGO:0045823 positive regulation of heart contraction ISO
 biological_processGO:0046580 negative regulation of Ras protein signal transduction IMP
 biological_processGO:0048103 somatic stem cell division IDA
 biological_processGO:0048468 cell development IBA
 biological_processGO:0048663 neuron fate commitment IDA
 biological_processGO:0048666 neuron development IMP
 biological_processGO:0048702 embryonic neurocranium morphogenesis ISO
 biological_processGO:0048839 inner ear development IMP
 biological_processGO:0050680 negative regulation of epithelial cell proliferation ISO
 biological_processGO:0050714 positive regulation of protein secretion ISO
 biological_processGO:0050777 negative regulation of immune response ISO
 biological_processGO:0051280 negative regulation of release of sequestered calcium ion into cytosol ISO
 biological_processGO:0051781 positive regulation of cell division IEA
 biological_processGO:0051794 regulation of timing of catagen ISO
 biological_processGO:0051795 positive regulation of timing of catagen ISO
 biological_processGO:0051891 positive regulation of cardioblast differentiation ISO
 biological_processGO:0060038 cardiac muscle cell proliferation ISO
 biological_processGO:0060065 uterus development IMP
 biological_processGO:0060317 cardiac epithelial to mesenchymal transition ISO
 biological_processGO:0060325 face morphogenesis IEP
 biological_processGO:0060389 pathway-restricted SMAD protein phosphorylation ISO
 biological_processGO:0060395 SMAD protein signal transduction ISO
 biological_processGO:0060412 ventricular septum morphogenesis TAS
 biological_processGO:0060413 atrial septum morphogenesis IMP
 biological_processGO:0061037 negative regulation of cartilage development IMP
 biological_processGO:0061626 pharyngeal arch artery morphogenesis IMP
 biological_processGO:0062009 secondary palate development IMP
 biological_processGO:0070237 positive regulation of activation-induced cell death of T cells IDA
 biological_processGO:0090091 positive regulation of extracellular matrix disassembly IDA
 biological_processGO:0097191 extrinsic apoptotic signaling pathway ISO
 biological_processGO:1900182 positive regulation of protein localization to nucleus IDA
 biological_processGO:1902256 regulation of apoptotic process involved in outflow tract morphogenesis IMP
 biological_processGO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II ISO
 biological_processGO:1903053 regulation of extracellular matrix organization IMP
 biological_processGO:1903701 substantia propria of cornea development IMP
 biological_processGO:1904426 positive regulation of GTP binding IDA
 biological_processGO:1904888 cranial skeletal system development IMP
 biological_processGO:1905006 negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation IMP
 biological_processGO:1905007 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation IMP
 biological_processGO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand IDA
 cellular_componentGO:0005576 extracellular region ISO
 cellular_componentGO:0005604 basement membrane ISO
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005768 endosome IDA
 cellular_componentGO:0005802 trans-Golgi network ISO
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0030141 secretory granule ISO
 cellular_componentGO:0030424 axon IDA
 cellular_componentGO:0043025 neuronal cell body IDA
 cellular_componentGO:0062023 collagen-containing extracellular matrix ISO
 molecular_functionGO:0001540 amyloid-beta binding ISO
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0005114 type II transforming growth factor beta receptor binding ISO
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005160 transforming growth factor beta receptor binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008083 growth factor activity TAS
 molecular_functionGO:0034714 type III transforming growth factor beta receptor binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0046982 protein heterodimerization activity ISO
 molecular_functionGO:0047485 protein N-terminus binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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