2281


Homo sapiens (NCBI)

Features
Gene ID: 2281
  
Biological name :
  
Synonyms : FK506 binding protein 1B / FKBP12.6|FKBP1L|OTK4|PKBP1L|PPIase / FKBP1B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 206857_s_at (Human Genome U133 Plus 2.0 Array)   209931_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_016859085.1
RefSeq - 1018443359
RefSeq - 1034612456
RefSeq - 1034612458
RefSeq - 1034612460
RefSeq - 1034612462
RefSeq - 17149839
RefSeq - 4758380
RefSeq - 767914174
RefSeq - NC_000002.12
RefSeq - NP_001309892.1
RefSeq - NP_001309893.1
RefSeq - NP_004107.1
RefSeq - NP_473374.1
RefSeq - XP_011531001.1
RefSeq - XP_016859082.1
RefSeq - XP_016859083.1
RefSeq - XP_016859084.1
RefSeq - 1018443357
RefSeq - NR_136538.1
RefSeq - NR_136539.1
RefSeq - XM_011532699.3
RefSeq - NM_001322963.1
RefSeq - NM_001322964.1
RefSeq - NM_004116.4
RefSeq - NM_054033.3
RefSeq - XM_017003593.2
RefSeq - XM_017003594.1
RefSeq - XM_017003595.2
RefSeq - XM_017003596.2
RefSeq - NR_136536.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000119782 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000413 protein peptidyl-prolyl isomerization IDA
 biological_processGO:0006458 "de novo" protein folding TAS
 biological_processGO:0006939 smooth muscle contraction IEA
 biological_processGO:0009749 response to glucose IEA
 biological_processGO:0010459 negative regulation of heart rate ISS
 biological_processGO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum IDA
 biological_processGO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion ISS
 biological_processGO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum IEA
 biological_processGO:0019227 neuronal action potential propagation IEA
 biological_processGO:0022417 protein maturation by protein folding TAS
 biological_processGO:0030073 insulin secretion IEA
 biological_processGO:0032515 negative regulation of phosphoprotein phosphatase activity IDA
 biological_processGO:0033197 response to vitamin E IEA
 biological_processGO:0034220 ion transmembrane transport TAS
 biological_processGO:0035584 calcium-mediated signaling using intracellular calcium source TAS
 biological_processGO:0042026 protein refolding TAS
 biological_processGO:0042098 T cell proliferation IEA
 biological_processGO:0042542 response to hydrogen peroxide IEA
 biological_processGO:0048680 positive regulation of axon regeneration IEA
 biological_processGO:0051280 negative regulation of release of sequestered calcium ion into cytosol IDA
 biological_processGO:0051284 positive regulation of sequestering of calcium ion IDA
 biological_processGO:0051480 regulation of cytosolic calcium ion concentration IGI
 biological_processGO:0051775 response to redox state IDA
 biological_processGO:0060314 regulation of ryanodine-sensitive calcium-release channel activity IMP
 biological_processGO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity IDA
 biological_processGO:0061077 chaperone-mediated protein folding IBA
 biological_processGO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus IEA
 biological_processGO:0086064 cell communication by electrical coupling involved in cardiac conduction TAS
 biological_processGO:1903779 regulation of cardiac conduction TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol IC
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0030018 Z disc IDA
 cellular_componentGO:0033017 sarcoplasmic reticulum membrane TAS
 cellular_componentGO:0034704 calcium channel complex IDA
 molecular_functionGO:0003755 peptidyl-prolyl cis-trans isomerase activity IDA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005219 ryanodine-sensitive calcium-release channel activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005528 FK506 binding IDA
 molecular_functionGO:0019855 calcium channel inhibitor activity IDA
 molecular_functionGO:0030551 cyclic nucleotide binding IEA
 molecular_functionGO:0044325 ion channel binding ISS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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