2332


Homo sapiens (NCBI)

Features
Gene ID: 2332
  
Biological name :
  
Synonyms : FMR1 / FMRP|FRAXA|POF|POF1 / fragile X mental retardation 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203689_s_at (Human Genome U133 Plus 2.0 Array)   215245_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NP_001172004.1
RefSeq - NP_001172005.1
RefSeq - NP_001172010.1
RefSeq - NP_001172011.1
RefSeq - NP_002015.1
RefSeq - NG_007529.2
RefSeq - 297374777
RefSeq - 297374779
RefSeq - 297374789
RefSeq - 297374791
RefSeq - 4503765
RefSeq - NC_000023.11
RefSeq - NR_033700.1
RefSeq - NM_001185075.1
RefSeq - NM_001185076.1
RefSeq - NM_001185081.1
RefSeq - NM_001185082.1
RefSeq - NM_002024.5
RefSeq - NR_033699.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000102081 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000381 regulation of alternative mRNA splicing, via spliceosome IDA
 biological_processGO:0001934 positive regulation of protein phosphorylation IBA
 biological_processGO:0002092 positive regulation of receptor internalization IDA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IDA
 biological_processGO:0007215 glutamate receptor signaling pathway ISS
 biological_processGO:0007417 central nervous system development IBA
 biological_processGO:0008089 anterograde axonal transport IBA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0017148 negative regulation of translation IBA
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0033129 positive regulation of histone phosphorylation IDA
 biological_processGO:0034644 cellular response to UV ISS
 biological_processGO:0043488 regulation of mRNA stability ISS
 biological_processGO:0044830 modulation by host of viral RNA genome replication IMP
 biological_processGO:0045727 positive regulation of translation IDA
 biological_processGO:0045947 negative regulation of translational initiation ISS
 biological_processGO:0046928 regulation of neurotransmitter secretion ISS
 biological_processGO:0048666 neuron development IBA
 biological_processGO:0048814 regulation of dendrite morphogenesis IBA
 biological_processGO:0051028 mRNA transport ISS
 biological_processGO:0051489 regulation of filopodium assembly IDA
 biological_processGO:0051491 positive regulation of filopodium assembly ISS
 biological_processGO:0060964 regulation of gene silencing by miRNA IMP
 biological_processGO:0060998 regulation of dendritic spine development IDA
 biological_processGO:0060999 positive regulation of dendritic spine development ISS
 biological_processGO:0072711 cellular response to hydroxyurea ISS
 biological_processGO:0098586 cellular response to virus IDA
 biological_processGO:0098908 regulation of neuronal action potential IDA
 biological_processGO:0099578 regulation of translation at postsynapse, modulating synaptic transmission IBA
 biological_processGO:1900453 negative regulation of long term synaptic depression ISS
 biological_processGO:1901254 positive regulation of intracellular transport of viral material IMP
 biological_processGO:1901386 negative regulation of voltage-gated calcium channel activity ISS
 biological_processGO:1901800 positive regulation of proteasomal protein catabolic process ISS
 biological_processGO:1902373 negative regulation of mRNA catabolic process IMP
 biological_processGO:1902416 positive regulation of mRNA binding IDA
 biological_processGO:1905244 regulation of modification of synaptic structure IBA
 biological_processGO:2000301 negative regulation of synaptic vesicle exocytosis ISS
 biological_processGO:2000637 positive regulation of gene silencing by miRNA IDA
 biological_processGO:2000766 negative regulation of cytoplasmic translation ISS
 biological_processGO:2001022 positive regulation of response to DNA damage stimulus IDA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005694 chromosome ISS
 cellular_componentGO:0005730 nucleolus TAS
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005844 polysome ISS
 cellular_componentGO:0005845 mRNA cap binding complex ISS
 cellular_componentGO:0010369 chromocenter ISS
 cellular_componentGO:0010494 cytoplasmic stress granule IEA
 cellular_componentGO:0014069 postsynaptic density ISS
 cellular_componentGO:0015030 Cajal body IEA
 cellular_componentGO:0016020 membrane IBA
 cellular_componentGO:0019034 viral replication complex IDA
 cellular_componentGO:0019897 extrinsic component of plasma membrane ISS
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0030426 growth cone IDA
 cellular_componentGO:0032433 filopodium tip ISS
 cellular_componentGO:0032797 SMN complex IDA
 cellular_componentGO:0035770 ribonucleoprotein granule IBA
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule IDA
 cellular_componentGO:0042734 presynaptic membrane IEA
 cellular_componentGO:0042788 polysomal ribosome TAS
 cellular_componentGO:0042995 cell projection IDA
 cellular_componentGO:0043005 neuron projection IDA
 cellular_componentGO:0043025 neuronal cell body IBA
 cellular_componentGO:0043197 dendritic spine ISS
 cellular_componentGO:0043204 perikaryon ISS
 cellular_componentGO:0043679 axon terminus ISS
 cellular_componentGO:0044295 axonal growth cone IBA
 cellular_componentGO:0044326 dendritic spine neck IBA
 cellular_componentGO:0045202 synapse ISS
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0071598 neuronal ribonucleoprotein granule ISS
 cellular_componentGO:0097386 glial cell projection ISS
 cellular_componentGO:0098793 presynapse ISS
 cellular_componentGO:0098794 postsynapse ISS
 cellular_componentGO:1902737 dendritic filopodium ISS
 cellular_componentGO:1990124 messenger ribonucleoprotein complex IDA
 cellular_componentGO:1990812 growth cone filopodium ISS
 cellular_componentGO:1990904 ribonucleoprotein complex IDA
 molecular_functionGO:0002151 G-quadruplex RNA binding IDA
 molecular_functionGO:0003682 chromatin binding ISS
 molecular_functionGO:0003723 RNA binding IMP
 molecular_functionGO:0003729 mRNA binding IDA
 molecular_functionGO:0003730 mRNA 3"-UTR binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding ISS
 molecular_functionGO:0008266 poly(U) RNA binding IDA
 molecular_functionGO:0030371 translation repressor activity IDA
 molecular_functionGO:0031369 translation initiation factor binding IPI
 molecular_functionGO:0033592 RNA strand annealing activity IDA
 molecular_functionGO:0034046 poly(G) binding IDA
 molecular_functionGO:0035064 methylated histone binding IDA
 molecular_functionGO:0035197 siRNA binding IDA
 molecular_functionGO:0035198 miRNA binding IDA
 molecular_functionGO:0035613 RNA stem-loop binding IDA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0043022 ribosome binding IPI
 molecular_functionGO:0044325 ion channel binding IPI
 molecular_functionGO:0045182 translation regulator activity IBA
 molecular_functionGO:0046982 protein heterodimerization activity IDA
 molecular_functionGO:0048027 mRNA 5"-UTR binding IDA
 molecular_functionGO:0070840 dynein complex binding ISS
 molecular_functionGO:1990825 sequence-specific mRNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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