2358


Homo sapiens (NCBI)
receptorregulationsignalingactivitymembranepathwayg-proteincoupledchemotaxisgranulecellactivationcomplementresponseerkmicroglialproteinphosphorylationmediatedreceptor-mediatedendocytosisinflammatoryadhesionadenylatecyclase-inhibitingphospholipasec-activatingcytosoliccalciumion

Features
Gene ID: 2358
  
Biological name :
  
Synonyms : ALXR|FMLP-R-II|FMLPX|FPR2A|FPRH1|FPRH2|FPRL1|HM63|LXA4R / formyl peptide receptor 2 / FPR2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 210772_at (Human Genome U133 Plus 2.0 Array)   210773_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4503781
RefSeq - 54112388
RefSeq - 578834215
RefSeq - NC_000019.10
RefSeq - NP_001005738.1
RefSeq - NP_001453.1
RefSeq - XP_006723183.1
RefSeq - NM_001005738.1
RefSeq - NM_001462.3
RefSeq - XM_006723120.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000171049 to get all the annotations available for this gene.


Gene Ontology (GO)
cell activationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processimmune responsecell communicationcellular response to stimulusestablishment of localizationresponse to external stimulusresponse to chemicalresponse to stresscell adhesionregulation of biological qualityimmune effector processanatomical structure developmentcellular developmental processlocalization of cellmovement of cell or subcellular componentbiosynthetic processregulation of molecular functionresponse to endogenous stimuluscell activationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processimmune responsecell communicationcellular response to stimulusestablishment of localizationresponse to external stimulusresponse to chemicalresponse to stresscell adhesionregulation of biological qualityimmune effector processanatomical structure developmentcellular developmental processlocalization of cellmovement of cell or subcellular componentbiosynthetic processregulation of molecular functionresponse to endogenous stimuluscell activationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processimmune responsecell communicationcellular response to stimulusestablishment of localizationresponse to external stimulusresponse to chemicalresponse to stresscell adhesionregulation of biological qualityimmune effector processanatomical structure developmentcellular developmental processlocalization of cellmovement of cell or subcellular componentbiosynthetic processregulation of molecular functionresponse to endogenous stimuluscell activationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processimmune responsecell communicationcellular response to stimulusestablishment of localizationresponse to external stimulusresponse to chemicalresponse to stresscell adhesionregulation of biological qualityimmune effector processanatomical structure developmentcellular developmental processlocalization of cellmovement of cell or subcellular componentbiosynthetic processregulation of molecular functionresponse to endogenous stimuluscell activationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processimmune responsecell communicationcellular response to stimulusestablishment of localizationresponse to external stimulusresponse to chemicalresponse to stresscell adhesionregulation of biological qualityimmune effector processanatomical structure developmentcellular developmental processlocalization of cellmovement of cell or subcellular componentbiosynthetic processregulation of molecular functionresponse to endogenous stimuluscell activationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processimmune responsecell communicationcellular response to stimulusestablishment of localizationresponse to external stimulusresponse to chemicalresponse to stresscell adhesionregulation of biological qualityimmune effector processanatomical structure developmentcellular developmental processlocalization of cellmovement of cell or subcellular componentbiosynthetic processregulation of molecular functionresponse to endogenous stimuluscell activationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processimmune responsecell communicationcellular response to stimulusestablishment of localizationresponse to external stimulusresponse to chemicalresponse to stresscell adhesionregulation of biological qualityimmune effector processanatomical structure developmentcellular developmental processlocalization of cellmovement of cell or subcellular componentbiosynthetic processregulation of molecular functionresponse to endogenous stimuluscell activationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processimmune responsecell communicationcellular response to stimulusestablishment of localizationresponse to external stimulusresponse to chemicalresponse to stresscell adhesionregulation of biological qualityimmune effector processanatomical structure developmentcellular developmental processlocalization of cellmovement of cell or subcellular componentbiosynthetic processregulation of molecular functionresponse to endogenous stimuluscell activationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processimmune responsecell communicationcellular response to stimulusestablishment of localizationresponse to external stimulusresponse to chemicalresponse to stresscell adhesionregulation of biological qualityimmune effector processanatomical structure developmentcellular developmental processlocalization of cellmovement of cell or subcellular componentbiosynthetic processregulation of molecular functionresponse to endogenous stimuluscell activationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processimmune responsecell communicationcellular response to stimulusestablishment of localizationresponse to external stimulusresponse to chemicalresponse to stresscell adhesionregulation of biological qualityimmune effector processanatomical structure developmentcellular developmental processlocalization of cellmovement of cell or subcellular componentbiosynthetic processregulation of molecular functionresponse to endogenous stimuluscell acell activationnitrognitrogen compound metabolic processcellulcellular metabolic processprimarprimary metabolic processorganiorganic substance metabolic processimmuneimmune responsecell ccell communicationcellulcellular response to stimulusestablestablishment of localizationresponresponse to external stimulusresponresponse to chemicalresponresponse to stresscell acell adhesionregularegulation of biological qualityimmuneimmune effector processanatomanatomical structure developmentcellulcellular developmental processlocalilocalization of cellmovememovement of cell or subcellular componentbiosynbiosynthetic processregularegulation of molecular functionresponresponse to endogenous stimulus
signaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activityprotein bindingsignaling receptor activitysignaling receptor activityprotein bindingprotein binding
cellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellcellmembranemembraneorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0001774 microglial cell activation ISS
 biological_processGO:0001934 positive regulation of protein phosphorylation IGI
 biological_processGO:0002430 complement receptor mediated signaling pathway IBA
 biological_processGO:0006898 receptor-mediated endocytosis ISS
 biological_processGO:0006935 chemotaxis TAS
 biological_processGO:0006954 inflammatory response TAS
 biological_processGO:0007155 cell adhesion TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway ISS
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IBA
 biological_processGO:0019722 calcium-mediated signaling IGI
 biological_processGO:0032930 positive regulation of superoxide anion generation ISS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0048143 astrocyte activation ISS
 biological_processGO:0050900 leukocyte migration IBA
 biological_processGO:0050918 positive chemotaxis ISS
 biological_processGO:0061903 positive regulation of 1-phosphatidylinositol-3-kinase activity ISS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISS
 biological_processGO:0090026 positive regulation of monocyte chemotaxis IGI
 biological_processGO:1904646 cellular response to amyloid-beta ISS
 cellular_componentGO:0005622 intracellular ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0070821 tertiary granule membrane TAS
 cellular_componentGO:0101003 ficolin-1-rich granule membrane TAS
 molecular_functionGO:0004875 complement receptor activity IBA
 molecular_functionGO:0004930 G-protein coupled receptor activity NAS
 molecular_functionGO:0004982 N-formyl peptide receptor activity IBA
 molecular_functionGO:0005124 scavenger receptor binding IPI
 molecular_functionGO:0038024 cargo receptor activity ISS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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