26585


Homo sapiens (NCBI)

Features
Gene ID: 26585
  
Biological name :
  
Synonyms : C15DUPq|CKTSF1B1|CRAC1|CRCS4|DAND2|DRM|DUP15q|GREMLIN|HMPS|HMPS1|IHG-2|MPSH|PIG2 / GREM1 / gremlin 1, DAN family BMP antagonist
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 218468_s_at (Human Genome U133 Plus 2.0 Array)   218469_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034590293
RefSeq - 300797307
RefSeq - 300797328
RefSeq - 7019349
RefSeq - NC_000015.10
RefSeq - NG_033791.1
RefSeq - NT_187660.1
RefSeq - NW_011332701.1
RefSeq - NW_012132920.1
RefSeq - XP_016877566.1
RefSeq - NP_001178251.1
RefSeq - NP_001178252.1
RefSeq - NP_037504.1
RefSeq - NM_001191322.1
RefSeq - NM_001191323.1
RefSeq - NM_013372.6
RefSeq - XM_017022077.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000166923 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000902 cell morphogenesis IDA
 biological_processGO:0001658 branching involved in ureteric bud morphogenesis IEA
 biological_processGO:0002042 cell migration involved in sprouting angiogenesis ISS
 biological_processGO:0002092 positive regulation of receptor internalization ISS
 biological_processGO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation ISS
 biological_processGO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007165 signal transduction ISS
 biological_processGO:0007171 activation of transmembrane receptor protein tyrosine kinase activity IEA
 biological_processGO:0007267 cell-cell signaling IEA
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0009954 proximal/distal pattern formation IEA
 biological_processGO:0010717 regulation of epithelial to mesenchymal transition IMP
 biological_processGO:0030199 collagen fibril organization IMP
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0030326 embryonic limb morphogenesis IEA
 biological_processGO:0030502 negative regulation of bone mineralization IMP
 biological_processGO:0030514 negative regulation of BMP signaling pathway IMP
 biological_processGO:0032331 negative regulation of chondrocyte differentiation IMP
 biological_processGO:0032872 regulation of stress-activated MAPK cascade ISS
 biological_processGO:0033689 negative regulation of osteoblast proliferation IMP
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0045668 negative regulation of osteoblast differentiation IMP
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0046851 negative regulation of bone remodeling IMP
 biological_processGO:0048263 determination of dorsal identity IMP
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0051893 regulation of focal adhesion assembly IEA
 biological_processGO:0051973 positive regulation of telomerase activity IDA
 biological_processGO:0060173 limb development IMP
 biological_processGO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation IDA
 biological_processGO:0060676 ureteric bud formation IEA
 biological_processGO:0061098 positive regulation of protein tyrosine kinase activity IEA
 biological_processGO:0072331 signal transduction by p53 class mediator ISS
 biological_processGO:0090027 negative regulation of monocyte chemotaxis ISS
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IDA
 biological_processGO:0090190 positive regulation of branching involved in ureteric bud morphogenesis IEA
 biological_processGO:0090191 negative regulation of branching involved in ureteric bud morphogenesis IEA
 biological_processGO:0090291 negative regulation of osteoclast proliferation IMP
 biological_processGO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation ISS
 biological_processGO:1900155 negative regulation of bone trabecula formation IMP
 biological_processGO:1900158 negative regulation of bone mineralization involved in bone maturation IMP
 biological_processGO:1901224 positive regulation of NIK/NF-kappaB signaling IEA
 biological_processGO:2000273 positive regulation of signaling receptor activity ISS
 biological_processGO:2000727 positive regulation of cardiac muscle cell differentiation ISS
 cellular_componentGO:0005615 extracellular space NAS
 cellular_componentGO:0009986 cell surface IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016015 morphogen activity ISS
 molecular_functionGO:0030297 transmembrane receptor protein tyrosine kinase activator activity ISS
 molecular_functionGO:0036122 BMP binding ISS
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0043184 vascular endothelial growth factor receptor 2 binding ISS
 molecular_functionGO:0048018 receptor ligand activity ISS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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