4734


Homo sapiens (NCBI)

Features
Gene ID: 4734
  
Biological name :
  
Synonyms : NEDD4 / NEDD4-1|RPF1 / neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 213012_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1042705510
RefSeq - 114520607
RefSeq - 114520609
RefSeq - 547234945
RefSeq - 547235255
RefSeq - 547235493
RefSeq - 767984288
RefSeq - 767984290
RefSeq - 767984292
RefSeq - NC_000015.10
RefSeq - NG_051072.1
RefSeq - NP_001271267.1
RefSeq - NP_001271268.1
RefSeq - NP_001271269.1
RefSeq - NP_001316141.1
RefSeq - NP_006145.2
RefSeq - NP_940682.2
RefSeq - XP_011519926.1
RefSeq - XP_011519927.1
RefSeq - XP_011519928.1
RefSeq - XM_011521624.3
RefSeq - NM_001284338.1
RefSeq - NM_001284339.1
RefSeq - NM_001284340.1
RefSeq - NM_001329212.1
RefSeq - NM_006154.3
RefSeq - NM_198400.3
RefSeq - XM_011521625.3
RefSeq - XM_011521626.1
RefSeq - NR_104302.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000069869 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IMP
 biological_processGO:0006622 protein targeting to lysosome IDA
 biological_processGO:0007041 lysosomal transport IDA
 biological_processGO:0007528 neuromuscular junction development IBA
 biological_processGO:0010766 negative regulation of sodium ion transport IDA
 biological_processGO:0010768 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage IMP
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IMP
 biological_processGO:0016241 regulation of macroautophagy TAS
 biological_processGO:0016567 protein ubiquitination IDA
 biological_processGO:0019089 transmission of virus IMP
 biological_processGO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway ISS
 biological_processGO:0031175 neuron projection development IEP
 biological_processGO:0031623 receptor internalization IDA
 biological_processGO:0032801 receptor catabolic process IDA
 biological_processGO:0034644 cellular response to UV IMP
 biological_processGO:0034765 regulation of ion transmembrane transport IDA
 biological_processGO:0042391 regulation of membrane potential IDA
 biological_processGO:0042921 glucocorticoid receptor signaling pathway IDA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IMP
 biological_processGO:0044111 development involved in symbiotic interaction IMP
 biological_processGO:0045732 positive regulation of protein catabolic process IDA
 biological_processGO:0046824 positive regulation of nucleocytoplasmic transport IDA
 biological_processGO:0048814 regulation of dendrite morphogenesis ISS
 biological_processGO:0050807 regulation of synapse organization IBA
 biological_processGO:0050847 progesterone receptor signaling pathway IDA
 biological_processGO:0051592 response to calcium ion TAS
 biological_processGO:0070534 protein K63-linked ubiquitination ISS
 biological_processGO:1901016 regulation of potassium ion transmembrane transporter activity IDA
 biological_processGO:2000650 negative regulation of sodium ion transmembrane transporter activity IDA
 cellular_componentGO:0000151 ubiquitin ligase complex ISS
 cellular_componentGO:0000785 chromatin IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IMP
 cellular_componentGO:0005938 cell cortex IDA
 cellular_componentGO:0016327 apicolateral plasma membrane TAS
 cellular_componentGO:0043197 dendritic spine IBA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019871 sodium channel inhibitor activity IDA
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0031698 beta-2 adrenergic receptor binding IDA
 molecular_functionGO:0043130 ubiquitin binding IDA
 molecular_functionGO:0050815 phosphoserine residue binding ISS
 molecular_functionGO:0050816 phosphothreonine residue binding ISS
 molecular_functionGO:0061630 ubiquitin protein ligase activity TAS
 molecular_functionGO:0070063 RNA polymerase binding IPI
 molecular_functionGO:0070064 proline-rich region binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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