4763


Homo sapiens (NCBI)

Features
Gene ID: 4763
  
Biological name :
  
Synonyms : neurofibromin 1 / NF1 / NFNS|VRNF|WSS
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204323_x_at (Human Genome U133 Plus 2.0 Array)   204325_s_at (Human Genome U133 Plus 2.0 Array)   210631_at (Human Genome U133 Plus 2.0 Array)   211094_s_at (Human Genome U133 Plus 2.0 Array)   211095_at (Human Genome U133 Plus 2.0 Array)   211914_x_at (Human Genome U133 Plus 2.0 Array)   212676_at (Human Genome U133 Plus 2.0 Array)   212678_at (Human Genome U133 Plus 2.0 Array)   216115_at (Human Genome U133 Plus 2.0 Array)   243476_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 109826564
RefSeq - 189458804
RefSeq - 4557793
RefSeq - NC_000017.11
RefSeq - NG_009018.1
RefSeq - NP_000258.1
RefSeq - NP_001035957.1
RefSeq - NP_001121619.1
RefSeq - NM_000267.3
RefSeq - NM_001042492.2
RefSeq - NM_001128147.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000196712 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0001649 osteoblast differentiation ISS
 biological_processGO:0001656 metanephros development ISS
 biological_processGO:0001666 response to hypoxia ISS
 biological_processGO:0001889 liver development ISS
 biological_processGO:0001937 negative regulation of endothelial cell proliferation IMP
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IEA
 biological_processGO:0001952 regulation of cell-matrix adhesion ISS
 biological_processGO:0001953 negative regulation of cell-matrix adhesion IEA
 biological_processGO:0006469 negative regulation of protein kinase activity ISS
 biological_processGO:0007154 cell communication ISS
 biological_processGO:0007265 Ras protein signal transduction ISS
 biological_processGO:0007406 negative regulation of neuroblast proliferation ISS
 biological_processGO:0007420 brain development ISS
 biological_processGO:0007422 peripheral nervous system development ISS
 biological_processGO:0007507 heart development ISS
 biological_processGO:0007519 skeletal muscle tissue development IEA
 biological_processGO:0008542 visual learning ISS
 biological_processGO:0008625 extrinsic apoptotic signaling pathway via death domain receptors IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0014044 Schwann cell development ISS
 biological_processGO:0014065 phosphatidylinositol 3-kinase signaling ISS
 biological_processGO:0016525 negative regulation of angiogenesis IEA
 biological_processGO:0021510 spinal cord development ISS
 biological_processGO:0021764 amygdala development IEA
 biological_processGO:0021897 forebrain astrocyte development ISS
 biological_processGO:0021915 neural tube development IEA
 biological_processGO:0021987 cerebral cortex development ISS
 biological_processGO:0022011 myelination in peripheral nervous system ISS
 biological_processGO:0030036 actin cytoskeleton organization ISS
 biological_processGO:0030198 extracellular matrix organization ISS
 biological_processGO:0030199 collagen fibril organization ISS
 biological_processGO:0030325 adrenal gland development ISS
 biological_processGO:0030336 negative regulation of cell migration IMP
 biological_processGO:0032228 regulation of synaptic transmission, GABAergic IEA
 biological_processGO:0034605 cellular response to heat IEA
 biological_processGO:0035021 negative regulation of Rac protein signal transduction IEA
 biological_processGO:0042060 wound healing ISS
 biological_processGO:0042308 negative regulation of protein import into nucleus IEA
 biological_processGO:0043065 positive regulation of apoptotic process ISS
 biological_processGO:0043087 regulation of GTPase activity IMP
 biological_processGO:0043407 negative regulation of MAP kinase activity ISS
 biological_processGO:0043409 negative regulation of MAPK cascade ISS
 biological_processGO:0043473 pigmentation ISS
 biological_processGO:0043525 positive regulation of neuron apoptotic process ISS
 biological_processGO:0043535 regulation of blood vessel endothelial cell migration IMP
 biological_processGO:0043547 positive regulation of GTPase activity ISS
 biological_processGO:0045124 regulation of bone resorption ISS
 biological_processGO:0045671 negative regulation of osteoclast differentiation IEA
 biological_processGO:0045685 regulation of glial cell differentiation ISS
 biological_processGO:0045762 positive regulation of adenylate cyclase activity ISS
 biological_processGO:0045765 regulation of angiogenesis IMP
 biological_processGO:0046929 negative regulation of neurotransmitter secretion IEA
 biological_processGO:0048147 negative regulation of fibroblast proliferation ISS
 biological_processGO:0048169 regulation of long-term neuronal synaptic plasticity IEA
 biological_processGO:0048485 sympathetic nervous system development ISS
 biological_processGO:0048593 camera-type eye morphogenesis ISS
 biological_processGO:0048712 negative regulation of astrocyte differentiation IEA
 biological_processGO:0048715 negative regulation of oligodendrocyte differentiation ISS
 biological_processGO:0048745 smooth muscle tissue development ISS
 biological_processGO:0048820 hair follicle maturation IEA
 biological_processGO:0048844 artery morphogenesis ISS
 biological_processGO:0048853 forebrain morphogenesis ISS
 biological_processGO:0050890 cognition IMP
 biological_processGO:0061534 gamma-aminobutyric acid secretion, neurotransmission IEA
 biological_processGO:0061535 glutamate secretion, neurotransmission IEA
 biological_processGO:0098597 observational learning IEA
 biological_processGO:1900271 regulation of long-term synaptic potentiation IEA
 biological_processGO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
 biological_processGO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0030424 axon IDA
 cellular_componentGO:0030425 dendrite IDA
 cellular_componentGO:0098793 presynapse IEA
 molecular_functionGO:0005096 GTPase activator activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008429 phosphatidylethanolamine binding IDA
 molecular_functionGO:0031210 phosphatidylcholine binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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