4921


Homo sapiens (NCBI)

Features
Gene ID: 4921
  
Biological name :
  
Synonyms : DDR2 / discoidin domain receptor tyrosine kinase 2 / MIG20a|NTRKR3|TKT|TYRO10
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 205168_at (Human Genome U133 Plus 2.0 Array)   225442_at (Human Genome U133 Plus 2.0 Array)   227561_at (Human Genome U133 Plus 2.0 Array)   235631_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1238789345
RefSeq - 1238789370
RefSeq - 62420884
RefSeq - 62420886
RefSeq - 767909403
RefSeq - 767909405
RefSeq - NC_000001.11
RefSeq - NG_016290.2
RefSeq - NP_001014796.1
RefSeq - NP_001341911.1
RefSeq - NP_001341912.1
RefSeq - NP_006173.2
RefSeq - XP_011507889.1
RefSeq - XP_011507890.1
RefSeq - NM_001014796.2
RefSeq - NM_001354982.1
RefSeq - NM_001354983.1
RefSeq - NM_006182.3
RefSeq - XM_011509587.2
RefSeq - XM_011509588.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000162733 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001503 ossification IEA
 biological_processGO:0003416 endochondral bone growth ISS
 biological_processGO:0007155 cell adhesion TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010715 regulation of extracellular matrix disassembly TAS
 biological_processGO:0010763 positive regulation of fibroblast migration TAS
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030198 extracellular matrix organization TAS
 biological_processGO:0030199 collagen fibril organization ISS
 biological_processGO:0030500 regulation of bone mineralization IMP
 biological_processGO:0031214 biomineral tissue development ISS
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0035988 chondrocyte proliferation TAS
 biological_processGO:0038063 collagen-activated tyrosine kinase receptor signaling pathway IDA
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0045669 positive regulation of osteoblast differentiation IMP
 biological_processGO:0045860 positive regulation of protein kinase activity IMP
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0048146 positive regulation of fibroblast proliferation ISS
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0090091 positive regulation of extracellular matrix disassembly ISS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0043235 receptor complex IBA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IBA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IDA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005518 collagen binding IDA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0038062 protein tyrosine kinase collagen receptor activity IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
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