50507


Homo sapiens (NCBI)

Features
Gene ID: 50507
  
Biological name :
  
Synonyms : KOX|KOX-1|RENOX / NADPH oxidase 4 / NOX4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 219773_at (Human Genome U133 Plus 2.0 Array)   236843_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_016873334.1
RefSeq - 1034573995
RefSeq - 1034573997
RefSeq - 1034573999
RefSeq - 1034574001
RefSeq - 219842346
RefSeq - 219842348
RefSeq - 578822229
RefSeq - 633257763
RefSeq - 633257765
RefSeq - 633257767
RefSeq - 665821293
RefSeq - 767970234
RefSeq - 8393843
RefSeq - NC_000011.10
RefSeq - NP_001137308.1
RefSeq - NP_001137309.1
RefSeq - NP_001278855.1
RefSeq - NP_001278856.1
RefSeq - NP_001278858.1
RefSeq - NP_001287924.1
RefSeq - NP_058627.1
RefSeq - XP_006718912.1
RefSeq - XP_011541159.1
RefSeq - XP_016873330.1
RefSeq - XP_016873331.1
RefSeq - XP_016873332.1
RefSeq - XP_016873333.1
RefSeq - 1034573991
RefSeq - NR_120406.1
RefSeq - NM_001143836.2
RefSeq - NM_001143837.1
RefSeq - NM_001291926.1
RefSeq - NM_001291927.1
RefSeq - NM_001291929.1
RefSeq - NM_001300995.1
RefSeq - NM_016931.4
RefSeq - XM_006718849.4
RefSeq - XM_011542857.2
RefSeq - XM_017017841.2
RefSeq - XM_017017842.1
RefSeq - XM_017017843.2
RefSeq - XM_017017844.1
RefSeq - XM_017017845.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000086991 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000902 cell morphogenesis ISS
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0003015 heart process IGI
 biological_processGO:0006801 superoxide metabolic process IDA
 biological_processGO:0006954 inflammatory response TAS
 biological_processGO:0007569 cell aging ISS
 biological_processGO:0008285 negative regulation of cell proliferation ISS
 biological_processGO:0010467 gene expression IMP
 biological_processGO:0014911 positive regulation of smooth muscle cell migration IEA
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0034599 cellular response to oxidative stress TAS
 biological_processGO:0042554 superoxide anion generation ISS
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043406 positive regulation of MAP kinase activity IEA
 biological_processGO:0045453 bone resorption IEA
 biological_processGO:0050667 homocysteine metabolic process IDA
 biological_processGO:0051496 positive regulation of stress fiber assembly IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling IEA
 biological_processGO:0055007 cardiac muscle cell differentiation IEA
 biological_processGO:0055114 oxidation-reduction process IDA
 biological_processGO:0061098 positive regulation of protein tyrosine kinase activity ISS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0071320 cellular response to cAMP IEA
 biological_processGO:0071333 cellular response to glucose stimulus IEA
 biological_processGO:0071480 cellular response to gamma radiation IEA
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus IEA
 biological_processGO:0072593 reactive oxygen species metabolic process IDA
 biological_processGO:1903409 reactive oxygen species biosynthetic process NAS
 biological_processGO:2000379 positive regulation of reactive oxygen species metabolic process IEA
 biological_processGO:2000573 positive regulation of DNA biosynthetic process IEA
 cellular_componentGO:0001725 stress fiber IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005739 mitochondrion ISS
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0043020 NADPH oxidase complex IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISS
 cellular_componentGO:0097038 perinuclear endoplasmic reticulum ISS
 molecular_functionGO:0000166 nucleotide binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0009055 electron transfer activity TAS
 molecular_functionGO:0016174 NAD(P)H oxidase activity TAS
 molecular_functionGO:0016175 superoxide-generating NADPH oxidase activity TAS
 molecular_functionGO:0019826 oxygen sensor activity TAS
 molecular_functionGO:0020037 heme binding TAS
 molecular_functionGO:0050660 flavin adenine dinucleotide binding TAS
 molecular_functionGO:0072341 modified amino acid binding IDA
 molecular_functionGO:1990782 protein tyrosine kinase binding ISS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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