5138


Homo sapiens (NCBI)

Features
Gene ID: 5138
  
Biological name :
  
Synonyms : CGS-PDE|PDE2A1|PED2A4|cGSPDE / PDE2A / phosphodiesterase 2A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204134_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 219802706
RefSeq - 226246591
RefSeq - 344925852
RefSeq - 4505657
RefSeq - 530396872
RefSeq - NC_000011.10
RefSeq - NP_001137311.1
RefSeq - NP_001139681.1
RefSeq - NP_001230713.1
RefSeq - NP_002590.1
RefSeq - XP_005274097.1
RefSeq - NM_001143839.3
RefSeq - NM_001146209.2
RefSeq - NM_001243784.1
RefSeq - NM_002599.4
RefSeq - XM_005274040.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000186642 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006198 cAMP catabolic process IMP
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0019933 cAMP-mediated signaling IMP
 biological_processGO:0019934 cGMP-mediated signaling IMP
 biological_processGO:0033159 negative regulation of protein import into nucleus, translocation IDA
 biological_processGO:0035690 cellular response to drug IMP
 biological_processGO:0036006 cellular response to macrophage colony-stimulating factor stimulus IDA
 biological_processGO:0043116 negative regulation of vascular permeability IMP
 biological_processGO:0043117 positive regulation of vascular permeability IMP
 biological_processGO:0043951 negative regulation of cAMP-mediated signaling IDA
 biological_processGO:0046069 cGMP catabolic process IDA
 biological_processGO:0050729 positive regulation of inflammatory response ISS
 biological_processGO:0061028 establishment of endothelial barrier ISS
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:0071260 cellular response to mechanical stimulus ISS
 biological_processGO:0071320 cellular response to cAMP IDA
 biological_processGO:0071321 cellular response to cGMP IDA
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus IEP
 biological_processGO:1904613 cellular response to 2,3,7,8-tetrachlorodibenzodioxine IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005741 mitochondrial outer membrane IDA
 cellular_componentGO:0005743 mitochondrial inner membrane IDA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISS
 cellular_componentGO:0005794 Golgi apparatus ISS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0042734 presynaptic membrane ISS
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0004112 cyclic-nucleotide phosphodiesterase activity IDA
 molecular_functionGO:0004115 3",5"-cyclic-AMP phosphodiesterase activity TAS
 molecular_functionGO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity IDA
 molecular_functionGO:0005262 calcium channel activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008144 drug binding IPI
 molecular_functionGO:0030552 cAMP binding IMP
 molecular_functionGO:0030553 cGMP binding IMP
 molecular_functionGO:0030911 TPR domain binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047555 3",5"-cyclic-GMP phosphodiesterase activity TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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