5727


Homo sapiens (NCBI)

Features
Gene ID: 5727
  
Biological name :
  
Synonyms : BCNS|NBCCS|PTC|PTC1|PTCH / patched 1 / PTCH1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1555520_at (Human Genome U133 Plus 2.0 Array)   208522_s_at (Human Genome U133 Plus 2.0 Array)   209815_at (Human Genome U133 Plus 2.0 Array)   209816_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NP_000255.2
RefSeq - NP_001077071.1
RefSeq - NP_001077072.1
RefSeq - NP_001077073.1
RefSeq - NP_001077074.1
RefSeq - NP_001077075.1
RefSeq - NP_001077076.1
RefSeq - NP_001341847.1
RefSeq - NP_001341848.1
RefSeq - 1237937711
RefSeq - NG_007664.1
RefSeq - 1237937983
RefSeq - 134254432
RefSeq - 134254435
RefSeq - 134254446
RefSeq - 134254450
RefSeq - 134254452
RefSeq - 134254466
RefSeq - 134254468
RefSeq - NC_000009.12
RefSeq - NR_149061.1
RefSeq - NM_000264.4
RefSeq - NM_001083602.2
RefSeq - NM_001083603.2
RefSeq - NM_001083604.2
RefSeq - NM_001083605.2
RefSeq - NM_001083606.2
RefSeq - NM_001083607.2
RefSeq - NM_001354918.1
RefSeq - NM_001354919.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000185920 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0001658 branching involved in ureteric bud morphogenesis IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001709 cell fate determination IEA
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0003007 heart morphogenesis IEA
 biological_processGO:0007224 smoothened signaling pathway ISS
 biological_processGO:0007346 regulation of mitotic cell cycle IEA
 biological_processGO:0007420 brain development ISS
 biological_processGO:0008589 regulation of smoothened signaling pathway ISS
 biological_processGO:0009612 response to mechanical stimulus IEA
 biological_processGO:0009887 animal organ morphogenesis ISS
 biological_processGO:0009953 dorsal/ventral pattern formation ISS
 biological_processGO:0009957 epidermal cell fate specification IEA
 biological_processGO:0010157 response to chlorate IEA
 biological_processGO:0010875 positive regulation of cholesterol efflux IDA
 biological_processGO:0016485 protein processing ISS
 biological_processGO:0021522 spinal cord motor neuron differentiation IEA
 biological_processGO:0021532 neural tube patterning IMP
 biological_processGO:0021997 neural plate axis specification ISS
 biological_processGO:0030326 embryonic limb morphogenesis ISS
 biological_processGO:0030850 prostate gland development IEA
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0032526 response to retinoic acid IEA
 biological_processGO:0032880 regulation of protein localization IEA
 biological_processGO:0035108 limb morphogenesis IMP
 biological_processGO:0035137 hindlimb morphogenesis IEA
 biological_processGO:0040015 negative regulation of multicellular organism growth ISS
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IMP
 biological_processGO:0043616 keratinocyte proliferation IEA
 biological_processGO:0045606 positive regulation of epidermal cell differentiation IEA
 biological_processGO:0045668 negative regulation of osteoblast differentiation IMP
 biological_processGO:0045879 negative regulation of smoothened signaling pathway TAS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0048568 embryonic organ development IEA
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IEA
 biological_processGO:0051782 negative regulation of cell division IEA
 biological_processGO:0060037 pharyngeal system development IMP
 biological_processGO:0060603 mammary gland duct morphogenesis IEA
 biological_processGO:0060644 mammary gland epithelial cell differentiation IEA
 biological_processGO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning IEA
 biological_processGO:0061005 cell differentiation involved in kidney development IEA
 biological_processGO:0061053 somite development IMP
 biological_processGO:0071397 cellular response to cholesterol ISS
 biological_processGO:0071679 commissural neuron axon guidance IEA
 biological_processGO:0072001 renal system development IEP
 biological_processGO:0072203 cell proliferation involved in metanephros development IEA
 biological_processGO:0072659 protein localization to plasma membrane IDA
 biological_processGO:0097421 liver regeneration IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005901 caveola IDA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0030666 endocytic vesicle membrane TAS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0044294 dendritic growth cone IEA
 cellular_componentGO:0044295 axonal growth cone IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0060170 ciliary membrane TAS
 molecular_functionGO:0005113 patched binding IEA
 molecular_functionGO:0005119 smoothened binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008158 hedgehog receptor activity IEA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0015485 cholesterol binding IDA
 molecular_functionGO:0030332 cyclin binding IPI
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0097108 hedgehog family protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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