6683


Homo sapiens (NCBI)

Features
Gene ID: 6683
  
Biological name :
  
Synonyms : ADPSP|FSP2|SPG4 / SPAST / spastin
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 207724_s_at (Human Genome U133 Plus 2.0 Array)   209748_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034616124
RefSeq - 1034616127
RefSeq - 11875211
RefSeq - 1393545649
RefSeq - 1393630394
RefSeq - 40806170
RefSeq - 530368010
RefSeq - 767915132
RefSeq - NC_000002.12
RefSeq - NG_008730.1
RefSeq - NP_001350752.1
RefSeq - NP_001350804.1
RefSeq - NP_055761.2
RefSeq - NP_955468.1
RefSeq - XP_005264573.1
RefSeq - XP_011531369.1
RefSeq - XP_016860266.1
RefSeq - XP_016860267.1
RefSeq - NM_001363823.1
RefSeq - NM_001363875.1
RefSeq - NM_014946.3
RefSeq - NM_199436.1
RefSeq - XM_005264516.5
RefSeq - XM_011533067.2
RefSeq - XM_017004777.2
RefSeq - XM_017004778.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000021574 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000281 mitotic cytokinesis IMP
 biological_processGO:0001578 microtubule bundle formation IDA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IMP
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0008089 anterograde axonal transport ISS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0010458 exit from mitosis IMP
 biological_processGO:0019896 axonal transport of mitochondrion ISS
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0031122 cytoplasmic microtubule organization IBA
 biological_processGO:0031468 nuclear envelope reassembly IMP
 biological_processGO:0032467 positive regulation of cytokinesis IMP
 biological_processGO:0032506 cytokinetic process IMP
 biological_processGO:0034214 protein hexamerization IDA
 biological_processGO:0051013 microtubule severing TAS
 biological_processGO:0051228 mitotic spindle disassembly IMP
 biological_processGO:0051260 protein homooligomerization IDA
 biological_processGO:0061640 cytoskeleton-dependent cytokinesis TAS
 biological_processGO:0090148 membrane fission IMP
 cellular_componentGO:0000815 ESCRT III complex TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005768 endosome IDA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005811 lipid droplet IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IDA
 cellular_componentGO:0030496 midbody IMP
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 cellular_componentGO:0031965 nuclear membrane IMP
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1904115 axon cytoplasm IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IDA
 molecular_functionGO:0008568 microtubule-severing ATPase activity IDA
 molecular_functionGO:0016887 ATPase activity IBA
 molecular_functionGO:0043014 alpha-tubulin binding IPI
 molecular_functionGO:0044877 protein-containing complex binding TAS
 molecular_functionGO:0048487 beta-tubulin binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr