7042


Homo sapiens (NCBI)

Features
Gene ID: 7042
  
Biological name :
  
Synonyms : G-TSF|LDS4|TGF-beta2 / TGFB2 / transforming growth factor beta 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 209908_s_at (Human Genome U133 Plus 2.0 Array)   209909_s_at (Human Genome U133 Plus 2.0 Array)   220406_at (Human Genome U133 Plus 2.0 Array)   220407_s_at (Human Genome U133 Plus 2.0 Array)   228121_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NP_001129071.1
RefSeq - NP_003229.1
RefSeq - NG_027721.2
RefSeq - 208022653
RefSeq - 4507463
RefSeq - NC_000001.11
RefSeq - NR_138149.1
RefSeq - NM_001135599.3
RefSeq - NM_003238.4
RefSeq - NR_138148.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000092969 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000902 cell morphogenesis IDA
 biological_processGO:0001501 skeletal system development ISS
 biological_processGO:0001525 angiogenesis TAS
 biological_processGO:0001654 eye development IDA
 biological_processGO:0001666 response to hypoxia IMP
 biological_processGO:0001822 kidney development ISS
 biological_processGO:0001837 epithelial to mesenchymal transition TAS
 biological_processGO:0001843 neural tube closure ISS
 biological_processGO:0001942 hair follicle development ISS
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0003007 heart morphogenesis IDA
 biological_processGO:0003148 outflow tract septum morphogenesis ISS
 biological_processGO:0003149 membranous septum morphogenesis ISS
 biological_processGO:0003179 heart valve morphogenesis ISS
 biological_processGO:0003181 atrioventricular valve morphogenesis ISS
 biological_processGO:0003184 pulmonary valve morphogenesis ISS
 biological_processGO:0003203 endocardial cushion morphogenesis ISS
 biological_processGO:0003215 cardiac right ventricle morphogenesis ISS
 biological_processGO:0003222 ventricular trabecula myocardium morphogenesis ISS
 biological_processGO:0003274 endocardial cushion fusion ISS
 biological_processGO:0003289 atrial septum primum morphogenesis ISS
 biological_processGO:0003407 neural retina development ISS
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0007050 cell cycle arrest IDA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IDA
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0007435 salivary gland morphogenesis IEP
 biological_processGO:0007507 heart development IDA
 biological_processGO:0008219 cell death IDA
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0008347 glial cell migration IDA
 biological_processGO:0008584 male gonad development ISS
 biological_processGO:0009611 response to wounding IEP
 biological_processGO:0009792 embryo development ending in birth or egg hatching TAS
 biological_processGO:0010002 cardioblast differentiation IDA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010629 negative regulation of gene expression IDA
 biological_processGO:0010634 positive regulation of epithelial cell migration IDA
 biological_processGO:0010693 negative regulation of alkaline phosphatase activity IDA
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition IDA
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IBA
 biological_processGO:0010936 negative regulation of macrophage cytokine production IDA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IDA
 biological_processGO:0016477 cell migration IDA
 biological_processGO:0016525 negative regulation of angiogenesis IDA
 biological_processGO:0030097 hemopoiesis ISS
 biological_processGO:0030199 collagen fibril organization IDA
 biological_processGO:0030307 positive regulation of cell growth IDA
 biological_processGO:0030308 negative regulation of cell growth IDA
 biological_processGO:0030326 embryonic limb morphogenesis ISS
 biological_processGO:0030593 neutrophil chemotaxis TAS
 biological_processGO:0031069 hair follicle morphogenesis ISS
 biological_processGO:0032147 activation of protein kinase activity IDA
 biological_processGO:0032570 response to progesterone IDA
 biological_processGO:0032874 positive regulation of stress-activated MAPK cascade IDA
 biological_processGO:0032909 regulation of transforming growth factor beta2 production IMP
 biological_processGO:0033630 positive regulation of cell adhesion mediated by integrin IDA
 biological_processGO:0035910 ascending aorta morphogenesis ISS
 biological_processGO:0042060 wound healing ISS
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0042416 dopamine biosynthetic process ISS
 biological_processGO:0042476 odontogenesis NAS
 biological_processGO:0042493 response to drug IDA
 biological_processGO:0042704 uterine wall breakdown TAS
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043408 regulation of MAPK cascade IBA
 biological_processGO:0043525 positive regulation of neuron apoptotic process IDA
 biological_processGO:0045216 cell-cell junction organization IDA
 biological_processGO:0045726 positive regulation of integrin biosynthetic process IDA
 biological_processGO:0045747 positive regulation of Notch signaling pathway IDA
 biological_processGO:0045778 positive regulation of ossification IEP
 biological_processGO:0045787 positive regulation of cell cycle ISS
 biological_processGO:0045823 positive regulation of heart contraction IDA
 biological_processGO:0046580 negative regulation of Ras protein signal transduction ISS
 biological_processGO:0048103 somatic stem cell division ISS
 biological_processGO:0048468 cell development IBA
 biological_processGO:0048566 embryonic digestive tract development IEP
 biological_processGO:0048666 neuron development ISS
 biological_processGO:0048699 generation of neurons TAS
 biological_processGO:0048839 inner ear development ISS
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IMP
 biological_processGO:0050714 positive regulation of protein secretion IDA
 biological_processGO:0050777 negative regulation of immune response TAS
 biological_processGO:0050778 positive regulation of immune response ISS
 biological_processGO:0051781 positive regulation of cell division IEA
 biological_processGO:0051794 regulation of timing of catagen IDA
 biological_processGO:0051795 positive regulation of timing of catagen IDA
 biological_processGO:0051891 positive regulation of cardioblast differentiation IDA
 biological_processGO:0060038 cardiac muscle cell proliferation IDA
 biological_processGO:0060065 uterus development ISS
 biological_processGO:0060317 cardiac epithelial to mesenchymal transition IDA
 biological_processGO:0060389 pathway-restricted SMAD protein phosphorylation IDA
 biological_processGO:0060395 SMAD protein signal transduction IDA
 biological_processGO:0060412 ventricular septum morphogenesis ISS
 biological_processGO:0060413 atrial septum morphogenesis ISS
 biological_processGO:0061626 pharyngeal arch artery morphogenesis ISS
 biological_processGO:0062009 secondary palate development ISS
 biological_processGO:0097191 extrinsic apoptotic signaling pathway IDA
 biological_processGO:1902256 regulation of apoptotic process involved in outflow tract morphogenesis ISS
 biological_processGO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II IDA
 biological_processGO:1903659 regulation of complement-dependent cytotoxicity IMP
 biological_processGO:1903701 substantia propria of cornea development ISS
 biological_processGO:1904888 cranial skeletal system development ISS
 biological_processGO:1905006 negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation ISS
 biological_processGO:1905007 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation ISS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0031093 platelet alpha granule lumen TAS
 cellular_componentGO:0043025 neuronal cell body ISS
 cellular_componentGO:0062023 collagen-containing extracellular matrix IDA
 molecular_functionGO:0001540 amyloid-beta binding IDA
 molecular_functionGO:0005102 signaling receptor binding IMP
 molecular_functionGO:0005114 type II transforming growth factor beta receptor binding IPI
 molecular_functionGO:0005125 cytokine activity TAS
 molecular_functionGO:0005160 transforming growth factor beta receptor binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0034714 type III transforming growth factor beta receptor binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046982 protein heterodimerization activity TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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