ENSDARG00000002445


Danio rerio

Features
Gene ID: ENSDARG00000002445
  
Biological name :prdm1a
  
Synonyms : prdm1a / PR domain containing 1a, with ZNF domain
  
Possible biological names infered from orthology : O75626 / PRDM1 / PR domain zinc finger protein 1 / PR/SET domain 1 / Q60636
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 7430998
Gene end: 7443388
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000004889
NCBI entrez gene - 323473     See in Manteia.
RefSeq - NM_199515
RefSeq Peptide - NP_955809
swissprot - Q68EH4
ZFIN ID - ZDB-GENE-030131-2193
Ensembl - ENSDARG00000002445
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000015388Gallus gallus
 PRDM1ENSG00000057657Homo sapiens
 Prdm1ENSMUSG00000038151Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
prdm1b / PR domain containing 1b, with ZNF domainENSDARG0000009892522
si:cabz01071911.3ENSDARG0000009099810


Protein motifs (from Interpro)
Interpro ID Name
 IPR001214  SET domain
 IPR013087  Zinc finger C2H2-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0000578 embryonic axis specification IMP
 biological_processGO:0007521 muscle cell fate determination IMP
 biological_processGO:0010629 negative regulation of gene expression IMP
 biological_processGO:0014032 neural crest cell development IMP
 biological_processGO:0014033 neural crest cell differentiation IMP
 biological_processGO:0033333 fin development IMP
 biological_processGO:0035118 embryonic pectoral fin morphogenesis IMP
 biological_processGO:0035138 pectoral fin morphogenesis IMP
 biological_processGO:0045666 positive regulation of neuron differentiation IMP
 biological_processGO:0048066 developmental pigmentation IMP
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IMP
 biological_processGO:0048702 embryonic neurocranium morphogenesis IGI
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 biological_processGO:0051155 positive regulation of striated muscle cell differentiation IMP
 biological_processGO:0060037 pharyngeal system development IMP
 biological_processGO:0060351 cartilage development involved in endochondral bone morphogenesis IMP
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000040 median fin fold median fin fold decreased length , abnormal
median fin fold increased thickness , abnormal
median fin fold deformed , abnormal
median fin fold rough , abnormal
Show

 ZFA:0000092 axis axis increased length , abnormal
Show

 ZFA:0000095 pharyngeal arch 3-7 skeleton pharyngeal arch 3-7 skeleton quality , abnormal
Show

 ZFA:0000108 fin fin malformed , abnormal
fin edge shape , abnormal
fin degenerate , abnormal
Show

 ZFA:0000135 notochord notochord quality , abnormal
notochord morphology , abnormal
Show

 ZFA:0000141 pectoral fin bud pectoral fin bud hypoplastic , abnormal
Show

 ZFA:0000155 somite somite increased width , abnormal
somite U-shaped , abnormal
somite quality , abnormal
somite morphology , abnormal
Show

 ZFA:0000184 cleithrum cleithrum decreased size , abnormal
Show

 ZFA:0000200 dorsal root ganglion dorsal root ganglion hypoplastic , abnormal
dorsal root ganglion lacks parts or has fewer parts of type neuron , abnormal
Show

 ZFA:0000292 surface structure surface structure quality , abnormal
Show

 ZFA:0000328 cephalic musculature cephalic musculature morphology , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0000578 ceratohyal bone ceratohyal bone inverted , abnormal
Show

 ZFA:0000608 ventral transverse ventral transverse aplastic , abnormal
Show

 ZFA:0000671 horizontal myoseptum horizontal myoseptum aplastic , abnormal
horizontal myoseptum absent , abnormal
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 ZFA:0000943 pectoral fin skeleton pectoral fin skeleton aplastic , abnormal
pectoral fin skeleton decreased size , abnormal
Show

 ZFA:0001058 caudal fin caudal fin mesenchyme hypoplastic , abnormal
Show

 ZFA:0001089 myoseptum myoseptum quality , abnormal
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 ZFA:0001094 whole organism whole organism wholly dorsalized , abnormal
whole organism has fewer parts of type pharyngeal pouch , abnormal
whole organism lacks all parts of type ceratobranchial 5 tooth , abnormal
whole organism lacks all parts of type ceratobranchial 2 cartilage , abnormal
whole organism lacks all parts of type ceratobranchial 3 cartilage , abnormal
whole organism lacks all parts of type ceratobranchial 4 cartilage , abnormal
whole organism lacks all parts of type ceratobranchial 5 cartilage , abnormal
whole organism lacks parts or has fewer parts of type dermal bone , abnormal
whole organism lethal (sensu genetics) , abnormal
whole organism movement behavioral quality , abnormal
whole organism viability , abnormal
whole organism decreased behavioural activity , abnormal
Show

 ZFA:0001106 pharyngeal pouch pharyngeal pouch disorganized , abnormal
Show

 ZFA:0001117 post-vent region post-vent region kinked , abnormal
Show

 ZFA:0001161 pectoral fin pectoral fin truncated , abnormal
pectoral fin rough , abnormal
Show

 ZFA:0001306 pharyngeal arch pharyngeal arch physical object quality , abnormal
pharyngeal arch decreased object quality , abnormal
pharyngeal arch cell proliferation decreased occurrence , abnormal
Show

 ZFA:0001321 neurocranial trabecula neurocranial trabecula shortened , abnormal
Show

 ZFA:0001373 migratory slow muscle precursor cell migratory slow muscle precursor cell decreased amount , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage inverted , abnormal
ceratohyal cartilage malformed , abnormal
Show

 ZFA:0001405 ethmoid cartilage ethmoid cartilage decreased size , abnormal
Show

 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage lacks all parts of type ceratobranchial 3 cartilage , abnormal
pharyngeal arch cartilage lacks all parts of type ceratobranchial 4 cartilage , abnormal
pharyngeal arch cartilage lacks all parts of type ceratobranchial 5 cartilage , abnormal
pharyngeal arch cartilage has fewer parts of type ceratobranchial cartilage , abnormal
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 ZFA:0001469 lateral line lateral line curved , abnormal
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 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage aplastic , abnormal
ceratobranchial cartilage absent , abnormal
ceratobranchial cartilage malformed , abnormal
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 ZFA:0001517 ceratobranchial 2 cartilage ceratobranchial 2 cartilage absent , abnormal
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 ZFA:0001518 ceratobranchial 3 cartilage ceratobranchial 3 cartilage absent , abnormal
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 ZFA:0001519 ceratobranchial 4 cartilage ceratobranchial 4 cartilage absent , abnormal
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 ZFA:0001521 ceratobranchial 5 cartilage ceratobranchial 5 cartilage absent , abnormal
Show

 ZFA:0001580 neurocranium neurocranium decreased width , abnormal
Show

 ZFA:0001606 pharyngeal arch 3 pharyngeal arch 3 decreased object quality , abnormal
Show

 ZFA:0001607 pharyngeal arch 4 pharyngeal arch 4 decreased object quality , abnormal
Show

 ZFA:0001617 otolith otolith decreased size , abnormal
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 ZFA:0005222 ventral larval melanophore stripe ventral larval melanophore stripe has fewer parts of type melanocyte , abnormal
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 ZFA:0005223 lateral larval melanophore stripe lateral larval melanophore stripe lacks all parts of type melanocyte , abnormal
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 ZFA:0005266 dorsal longitudinal fasciculus dorsal longitudinal fasciculus hypoplastic , abnormal
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 ZFA:0007067 vagal ganglion vagal ganglion malformed , abnormal
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 ZFA:0009090 pigment cell pigment cell decreased amount , abnormal
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 ZFA:0009091 melanocyte melanocyte irregular spatial pattern , abnormal
melanocyte decreased amount , abnormal
melanocyte low saturation , abnormal
melanocyte degenerate , abnormal
melanocyte decreased pigmentation , abnormal
melanocyte quality , abnormal
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 ZFA:0009116 slow muscle cell slow muscle cell absent , abnormal
slow muscle cell multinucleate , abnormal
Show

 ZFA:0009150 Rohon-Beard neuron Rohon-Beard neuron absent , abnormal
Rohon-Beard neuron aplastic , abnormal
Show

 ZFA:0009198 xanthophore xanthophore desaturated yellow , abnormal
xanthophore decreased pigmentation , abnormal
xanthophore decreased amount , abnormal
Show

 ZFA:0009199 iridophore iridophore low saturation , abnormal
iridophore decreased pigmentation , abnormal
iridophore decreased amount , abnormal
Show

 ZFA:0009247 secondary motor neuron secondary motor neuron morphology , abnormal
secondary motor neuron defasciculated , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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