ENSDARG00000004130


Danio rerio

Features
Gene ID: ENSDARG00000004130
  
Biological name :mvk
  
Synonyms : mevalonate kinase / mvk
  
Possible biological names infered from orthology : Q03426 / Q9R008
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 19494198
Gene end: 19509695
  
Corresponding Affymetrix probe sets: Dr.14909.1.A1_at (Zebrafish Array)   NM_001007349_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000019792
NCBI entrez gene - 492477     See in Manteia.
RefSeq - NM_001007349
RefSeq Peptide - NP_001007350
swissprot - A2BGN1
ZFIN ID - ZDB-GENE-041114-37
Ensembl - ENSDARG00000004130
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MVKENSGALG00000013848Gallus gallus
 MVKENSG00000110921Homo sapiens
 MvkENSMUSG00000041939Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006203  GHMP kinase, ATP-binding, conserved site
 IPR006204  GHMP kinase N-terminal domain
 IPR006205  Mevalonate kinase
 IPR013750  GHMP kinase, C-terminal domain
 IPR014721  Ribosomal protein S5 domain 2-type fold, subgroup
 IPR020568  Ribosomal protein S5 domain 2-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006694 steroid biosynthetic process IEA
 biological_processGO:0006695 cholesterol biosynthetic process IBA
 biological_processGO:0008202 steroid metabolic process IEA
 biological_processGO:0008203 cholesterol metabolic process IEA
 biological_processGO:0008299 isoprenoid biosynthetic process IEA
 biological_processGO:0016126 sterol biosynthetic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004496 mevalonate kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Cholesterol biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000004130 mvk / mevalonate kinase / Q03426* / Q9R008*  / complex






 

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