ENSDARG00000006011


Danio rerio

Features
Gene ID: ENSDARG00000006011
  
Biological name :klhl42
  
Synonyms : kelch-like family, member 42 / klhl42
  
Possible biological names infered from orthology : Kelch-like protein 42 / Q8BFQ9 / Q9P2K6
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 17634311
Gene end: 17642168
  
Corresponding Affymetrix probe sets: Dr.18975.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000014696
swissprot - Q5RGJ4
ZFIN ID - ZDB-GENE-041210-190
Ensembl - ENSDARG00000006011
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KLHL42ENSGALG00000017296Gallus gallus
 KLHL42ENSG00000087448Homo sapiens
 Klhl42ENSMUSG00000040102Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
klhdc7a / kelch domain containing 7A / A2APT9* / Q5VTJ3* / Kelch domain-containing protein 7A *ENSDARG0000010532217
kbtbd11 / kelch repeat and BTB (POZ) domain containing 11 / Q8BNW9* / O94819* / kelch repeat and BTB domain containing 11* / Kelch repeat and BTB domain-containing protein 11 *ENSDARG0000010495817
si:ch211-253p14.2 / Q8C828* / C9JR72* / KBTBD13* / kelch repeat and BTB domain containing 13* / Kelch repeat and BTB domain-containing protein 13 *ENSDARG0000001390716
BX276107.1ENSDARG0000011313715
kbtbd13 / kelch repeat and BTB (POZ) domain containing 13 / C9JR72* / Q8C828* / kelch repeat and BTB domain containing 13* / Kelch repeat and BTB domain-containing protein 13 *ENSDARG0000007644913


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR015915  Kelch-type beta propeller


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0031018 endocrine pancreas development IMP
 biological_processGO:0032886 regulation of microtubule-based process IBA
 biological_processGO:0042593 glucose homeostasis IMP
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IBA
 biological_processGO:1990798 pancreas regeneration IMP
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001260 endocrine pancreas endocrine pancreas decreased size , abnormal
endocrine pancreas decreased distribution , abnormal
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 ZFA:0009102 pancreatic B cell pancreatic B cell increased amount , abnormal
pancreatic B cell decreased amount , abnormal
pancreatic B cell decreased area , abnormal
pancreatic B cell regeneration decreased rate , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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