ENSG00000087448


Homo sapiens

Features
Gene ID: ENSG00000087448
  
Biological name :KLHL42
  
Synonyms : kelch like family member 42 / KLHL42 / Q9P2K6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: p11.22
Gene start: 27780020
Gene end: 27803040
  
Corresponding Affymetrix probe sets: 225732_at (Human Genome U133 Plus 2.0 Array)   225961_at (Human Genome U133 Plus 2.0 Array)   225963_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000444748
Ensembl peptide - ENSP00000370671
Ensembl peptide - ENSP00000443934
NCBI entrez gene - 57542     See in Manteia.
RefSeq - XM_017019698
RefSeq - NM_020782
RefSeq Peptide - NP_065833
swissprot - H0YGN2
swissprot - B2RNT7
swissprot - Q9P2K6
swissprot - F5H523
Ensembl - ENSG00000087448
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 klhl42ENSDARG00000006011Danio rerio
 KLHL42ENSGALG00000017296Gallus gallus
 Klhl42ENSMUSG00000040102Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96G42 / KLHDC7B / kelch domain containing 7BENSG0000013048719
Q5VTJ3 / KLHDC7A / kelch domain containing 7AENSG0000017902317
O94819 / KBTBD11 / kelch repeat and BTB domain containing 11ENSG0000017659517
C9JR72 / KBTBD13 / kelch repeat and BTB domain containing 13ENSG0000023443815


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller
 IPR037293  Galactose oxidase, central domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IDA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0032886 regulation of microtubule-based process IMP
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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